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Protein

C-C motif chemokine

Gene

Ccl17

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. CCR4 chemokine receptor binding Source: RGD

GO - Biological processi

  1. cell chemotaxis Source: GOC
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CytokineUniRule annotationSAAS annotation

Keywords - Biological processi

ChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:Ccl17Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi619924. Ccl17.

Subcellular locationi

Secreted UniRule annotation

GO - Cellular componenti

  1. extracellular space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323UniRule annotationAdd
BLAST
Chaini24 – 9370C-C motif chemokineUniRule annotationPRO_5001353863Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ9ERE0.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021842.

Structurei

3D structure databases

ProteinModelPortaliQ9ERE0.
SMRiQ9ERE0. Positions 25-90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiNOG45053.
HOGENOMiHOG000036685.
HOVERGENiHBG098492.
KOiK05514.
PhylomeDBiQ9ERE0.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ERE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSLQMLLLA ALLLGTSLQH ASAARATNVG RECCLDYFKG AIPIRKLVTW
60 70 80 90
FRTSVECPKD AIVFETVQGR LICTDPKDKH VKKAIRHLKN QRL
Length:93
Mass (Da):10,480
Last modified:March 1, 2001 - v1
Checksum:i7274345889EE4889
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312687 mRNA. Translation: AAG31159.1.
RefSeqiNP_476492.1. NM_057151.1.
UniGeneiRn.46679.

Genome annotation databases

GeneIDi117518.
KEGGirno:117518.
UCSCiRGD:619924. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312687 mRNA. Translation: AAG31159.1.
RefSeqiNP_476492.1. NM_057151.1.
UniGeneiRn.46679.

3D structure databases

ProteinModelPortaliQ9ERE0.
SMRiQ9ERE0. Positions 25-90.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021842.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi117518.
KEGGirno:117518.
UCSCiRGD:619924. rat.

Organism-specific databases

CTDi6361.
RGDi619924. Ccl17.

Phylogenomic databases

eggNOGiNOG45053.
HOGENOMiHOG000036685.
HOVERGENiHBG098492.
KOiK05514.
PhylomeDBiQ9ERE0.

Miscellaneous databases

NextBioi620283.

Gene expression databases

GenevestigatoriQ9ERE0.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "cDNA cloning and analysis of tissue-specific mRNA expression of rat thymus-and activation-regulated chemokine."
    Park J.H., Ju S.K.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.
    Tissue: ThymusImported.

Entry informationi

Entry nameiQ9ERE0_RAT
AccessioniPrimary (citable) accession number: Q9ERE0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: March 4, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.