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Protein

SERTA domain-containing protein 3

Gene

Sertad3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Strong transcriptional coactivator.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
SERTA domain-containing protein 3
Alternative name(s):
Replication protein-binding trans-activator
Short name:
RPA-binding trans-activator
Gene namesi
Name:Sertad3
Synonyms:Rbt1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2180697. Sertad3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001916161 – 197SERTA domain-containing protein 3Add BLAST197

Proteomic databases

PaxDbiQ9ERC3.
PRIDEiQ9ERC3.

PTM databases

iPTMnetiQ9ERC3.
PhosphoSitePlusiQ9ERC3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000055200.
CleanExiMM_SERTAD3.
ExpressionAtlasiQ9ERC3. baseline and differential.
GenevisibleiQ9ERC3. MM.

Interactioni

Subunit structurei

Interacts with RPA2.By similarity

Protein-protein interaction databases

BioGridi228408. 1 interactor.
STRINGi10090.ENSMUSP00000068187.

Structurei

3D structure databases

ProteinModelPortaliQ9ERC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 74SERTAPROSITE-ProRule annotationAdd BLAST48

Sequence similaritiesi

Contains 1 SERTA domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410JAJA. Eukaryota.
ENOG41119NJ. LUCA.
GeneTreeiENSGT00730000111546.
HOGENOMiHOG000133073.
HOVERGENiHBG055009.
InParanoidiQ9ERC3.
OMAiEDEKWDW.
OrthoDBiEOG091G0U23.
PhylomeDBiQ9ERC3.
TreeFamiTF101069.

Family and domain databases

InterProiIPR009263. SERTA_dom.
[Graphical view]
PfamiPF06031. SERTA. 1 hit.
[Graphical view]
PROSITEiPS51053. SERTA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ERC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGLKRKHSD LEEEEEEEKW DWSPTALRSY QQALLRISLD KVQRSLGPRA
60 70 80 90 100
PSLRRHVLIH NTLQQLQAAI RLAPAPALPP EPLFLGEEDF SLSTTIGSIL
110 120 130 140 150
RELDTSMDEM EPPLNPAASS SPQNEIVSQA DPVFLEALSS RYLGDSGLDD
160 170 180 190
FFLDIDTSAV EKDVALPPPE PPHSLFCSPG SWEWNELDHI MEIILGS
Length:197
Mass (Da):21,935
Last modified:March 1, 2001 - v1
Checksum:iCFF6FA4C0A91D7E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF317202 mRNA. Translation: AAG30951.1.
BC034886 mRNA. Translation: AAH34886.1.
CCDSiCCDS21021.1.
RefSeqiNP_573473.1. NM_133210.2.
UniGeneiMm.200120.

Genome annotation databases

EnsembliENSMUST00000068641; ENSMUSP00000068187; ENSMUSG00000055200.
GeneIDi170742.
KEGGimmu:170742.
UCSCiuc009fwg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF317202 mRNA. Translation: AAG30951.1.
BC034886 mRNA. Translation: AAH34886.1.
CCDSiCCDS21021.1.
RefSeqiNP_573473.1. NM_133210.2.
UniGeneiMm.200120.

3D structure databases

ProteinModelPortaliQ9ERC3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi228408. 1 interactor.
STRINGi10090.ENSMUSP00000068187.

PTM databases

iPTMnetiQ9ERC3.
PhosphoSitePlusiQ9ERC3.

Proteomic databases

PaxDbiQ9ERC3.
PRIDEiQ9ERC3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000068641; ENSMUSP00000068187; ENSMUSG00000055200.
GeneIDi170742.
KEGGimmu:170742.
UCSCiuc009fwg.1. mouse.

Organism-specific databases

CTDi29946.
MGIiMGI:2180697. Sertad3.

Phylogenomic databases

eggNOGiENOG410JAJA. Eukaryota.
ENOG41119NJ. LUCA.
GeneTreeiENSGT00730000111546.
HOGENOMiHOG000133073.
HOVERGENiHBG055009.
InParanoidiQ9ERC3.
OMAiEDEKWDW.
OrthoDBiEOG091G0U23.
PhylomeDBiQ9ERC3.
TreeFamiTF101069.

Miscellaneous databases

PROiQ9ERC3.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055200.
CleanExiMM_SERTAD3.
ExpressionAtlasiQ9ERC3. baseline and differential.
GenevisibleiQ9ERC3. MM.

Family and domain databases

InterProiIPR009263. SERTA_dom.
[Graphical view]
PfamiPF06031. SERTA. 1 hit.
[Graphical view]
PROSITEiPS51053. SERTA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSRTD3_MOUSE
AccessioniPrimary (citable) accession number: Q9ERC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.