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Protein

Protein YIPF5

Gene

Yipf5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Plays a role in transport between endoplasmic reticulum and Golgi.By similarity

GO - Biological processi

  • protein transport Source: UniProtKB-KW
  • regulation of ER to Golgi vesicle-mediated transport Source: MGI
  • vesicle-mediated transport Source: UniProtKB-KW

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIPF5
Alternative name(s):
YIP1 family member 5
YPT-interacting protein 1 A
Gene namesi
Name:Yipf5
Synonyms:Yip1a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1914430. Yipf5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 124CytoplasmicSequence analysisAdd BLAST124
Transmembranei125 – 145HelicalSequence analysisAdd BLAST21
Topological domaini146LumenalSequence analysis1
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 173CytoplasmicSequence analysis6
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 196LumenalSequence analysis2
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 236CytoplasmicSequence analysisAdd BLAST19
Transmembranei237 – 257HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002343301 – 257Protein YIPF5Add BLAST257

Proteomic databases

EPDiQ9EQQ2.
MaxQBiQ9EQQ2.
PaxDbiQ9EQQ2.
PeptideAtlasiQ9EQQ2.
PRIDEiQ9EQQ2.

PTM databases

iPTMnetiQ9EQQ2.
PhosphoSitePlusiQ9EQQ2.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

BgeeiENSMUSG00000024487.
CleanExiMM_YIPF5.
GenevisibleiQ9EQQ2. MM.

Interactioni

Subunit structurei

Interacts with the COPII coat components Sec23 (SEC23A and/or SEC23B) and Sec24 (SEC24A and/or SEC24B). Interacts with YIF1A. May interact with RAB1A (By similarity).By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025364.

Structurei

3D structure databases

ProteinModelPortaliQ9EQQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni75 – 106Interaction with Sec23By similarityAdd BLAST32

Sequence similaritiesi

Belongs to the YIP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3103. Eukaryota.
COG5080. LUCA.
GeneTreeiENSGT00510000046817.
HOGENOMiHOG000037706.
HOVERGENiHBG055241.
InParanoidiQ9EQQ2.
KOiK20363.
OMAiFDNLNTD.
OrthoDBiEOG091G0Y2Z.
PhylomeDBiQ9EQQ2.
TreeFamiTF313100.

Family and domain databases

InterProiView protein in InterPro
IPR006977. Yip1.
PfamiView protein in Pfam
PF04893. Yip1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9EQQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGFDNLNSG FYQTSYSIDE QSQQSYDYGG SGGPYSKQYA GCDYSQQGRF
60 70 80 90 100
VPPDMMQPQQ TYTGQIYQPT QAYPPTTPQP FYGDSFEEEP PLLEELGINF
110 120 130 140 150
DHIWQKTLTV LHPLRAADGS IMNETDLAGP VVFCLAFGAT LLLAGKIQFG
160 170 180 190 200
YVYGISAIGC LGMFCLLNLM SMTGVSFGCV ASVLGYCLLP MILLSSFAVV
210 220 230 240 250
FSLQGMVGIL LTATIIGWCS FSASKIFISA LAMDGQQLLV AYPCALLYGV

FALISVF
Length:257
Mass (Da):27,873
Last modified:March 1, 2001 - v1
Checksum:i792206E7E4B39190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF140226 mRNA. Translation: AAG48522.1.
AK010089 mRNA. Translation: BAB26694.1.
AK151425 mRNA. Translation: BAE30389.1.
AK151461 mRNA. Translation: BAE30419.1.
AK152440 mRNA. Translation: BAE31221.1.
AK153123 mRNA. Translation: BAE31738.1.
AK160004 mRNA. Translation: BAE35552.1.
AK167526 mRNA. Translation: BAE39596.1.
BC003317 mRNA. Translation: AAH03317.1.
BC055301 mRNA. Translation: AAH55301.1.
CCDSiCCDS29207.1.
RefSeqiNP_075800.1. NM_023311.3.
UniGeneiMm.270382.

Genome annotation databases

EnsembliENSMUST00000025364; ENSMUSP00000025364; ENSMUSG00000024487.
GeneIDi67180.
KEGGimmu:67180.
UCSCiuc008etd.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiYIPF5_MOUSE
AccessioniPrimary (citable) accession number: Q9EQQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: March 1, 2001
Last modified: May 10, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families