Unreviewed, UniProtKB/TrEMBL Q9EQL1 (Q9EQL1_MOUSE)

Names and origin

Protein names

Submitted name:
    Phosphatidylinositol 3-kinase gamma isoform EMBL AAG41122.1

Gene names

Name:

Pik3cg EMBL AAG41122.1

Organism

Mus musculus (Mouse) EMBL AAG41122.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1113 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PI3K/PI4K domain. Spearmint SPM000403

Ontologies

Keywords
Molecular function	Kinase Spearmint SPM000403 EMBL AAG41122.1 Transferase
Gene Ontology (GO)
Biological process	negative regulation of apoptosis Inferred from direct assay. Source: MGI phosphoinositide phosphorylation Inferred from electronic annotation. Source: InterPro phosphoinositide-mediated signaling Inferred from electronic annotation. Source: InterPro protein amino acid phosphorylation Inferred from direct assay. Source: MGI
Cellular component	phosphoinositide 3-kinase complex Inferred from electronic annotation. Source: InterPro
Molecular function	1-phosphatidylinositol-3-kinase activity Inferred from electronic annotation. Source: InterPro binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9EQL1-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 6729FE8EA5D35691	FASTA	1,113	127,540
	10 20 30 40 50 60 MELENYEQPV VLREDNLRRR RRMKPRSAAG SLSSMELIPI EFVLPTSQRI SKTPETALLH 70 80 90 100 110 120 VAGHGNVEQM KAQVWLRALE TSVAAEFYHR LGPDQFLLLY QKKGQWYEIY DRYQVVQTLD 130 140 150 160 170 180 CLHYWKLMHK SPGQIHVVQR HVPSEETLAF QKQLTSLIGY DVTDISNVHD DELEFTRRRL 190 200 210 220 230 240 VTPRMAEVAG RDAKLYAMHP WVTSKPLPDY LSKKIANNCI FIVIHRGTTS QTIKVSADDT 250 260 270 280 290 300 PGTILQSFFT KMAKKKSLMN ISESQSEQDF VLRVCGRDEY LVGETPLKNF QWVRQCLKNG 310 320 330 340 350 360 DEIHLVLDTP PDPALDEVRK EEWPLVDDCT GVTGYHEQLT IHGKDHESVF TVSLWDCDRK 370 380 390 400 410 420 FRVKIRGIDI PVLPRNTDLT VFVEANIQHG QQVLCQRRTS PKPFAEEVLW NVWLEFGIKI 430 440 450 460 470 480 KDLPKGALLN LQIYCCKTPS LSSKASAETP GSESKGKAQL LYYVNLLLID HRFLLRHGDY 490 500 510 520 530 540 VLHMWQISGK AEEQGSFNAD KLTSATNPDK ENSMSISILL DNYCHPIALP KHRPTPDPEG 550 560 570 580 590 600 DRVRAEMPNQ LRKQLEAIIA TDPLNPLTAE DKELLWHFRY ESLKHPKAYP KLFSSVKWGQ 610 620 630 640 650 660 QEIVAKTYQL LARREIWDQS ALDVGLTMQL LDCNFSDENV RAIAVQKLES LEDDDVLHYL 670 680 690 700 710 720 LQLVQAVKFE PYHDSALARF LLKRGLRNKR IGHFLFWFLR SEIAQSXHYQ QRFAVILEAY 730 740 750 760 770 780 LRGCGTAMLQ DFTQQVHVIE MLQKVTIDIK SLSAEKYDVS SQVISQLKQK LESLQNSNLP 790 800 810 820 830 840 ESFRVPYDPG LKAGTLVIEK CKVMASKKKP LWLEFKCADP TVLSNETIGI IFKHGDDLRQ 850 860 870 880 890 900 DMLILQILRI MESIWETESL DLCLLPYGCI STGDKIGMIE IVKDATTIAQ IQQSTVGNTG 910 920 930 940 950 960 AFKDEVLNHW LKEKCPIEEK FQAAVERFVY SCAGYCVATF VLGIGDRHND NIMISETGNL 970 980 990 1000 1010 1020 FHIDFGHILG NYKSFLGINK ERVPFVLTPD FLVVMGSSGK KTSPHFQKFQ DCCVSTLQYY 1030 1040 1050 1060 1070 1080 GDVCVRAYLA LRHHTNLLII LFSMMLMTGM PQLTSKEDIE YIRDALTVGK SEEDAKKYFL 1090 1100 1110 DQIEVCRDKG WTVQFNWFLH LVLGIKQGEK HSA

References

[1]	"Cloning of a murine ortholog of PI 3-kinase gamma." Chakravarti S., McColl S.R. Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BALB/c EMBL AAG41122.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF208345 mRNA. Translation: AAG41122.1.
IPI	IPI00468012.
UniGene	Mm.101369 Mm.404021
3D structure databases
HSSP	HSSP built from PDB template 1E7U based on UniProtKB O02697.
SMR	Q9EQL1. Positions 144-1105.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9EQL1.
Proteomic databases
PRIDE	Q9EQL1.
Genome annotation databases
Ensembl	ENSMUST00000020890; ENSMUSP00000020890; ENSMUSG00000020573; Mus musculus. [Genome view] ENSMUST00000053215; ENSMUSP00000062864; ENSMUSG00000020573; Mus musculus. [Genome view] ENSMUST00000085469; ENSMUSP00000082596; ENSMUSG00000020573; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:1353576. Pik3cg.
Phylogenomic databases
HOGENOM	Q9EQL1.
HOVERGEN	Q9EQL1.
Gene expression databases
ArrayExpress	Q9EQL1.
Bgee	Q9EQL1.
Genevestigator	Q9EQL1.
Family and domain databases
InterPro	IPR016024. ARM-type_fold. IPR008973. C2_Ca/lipid-bd_reg_CaLB. IPR011009. Kinase-like_dom. IPR000403. PI3/4_kinase_cat. IPR018936. PI3/4_kinase_CS. IPR002420. PI3K_C2. IPR000341. PI3K_ras_bd. IPR001263. PI3Ka. IPR015433. PI_Kinase. [Graphical view]
Gene3D	G3DSA:1.10.1070.11. PI3/4_kinase_cat. 1 hit. G3DSA:1.25.40.70. PI3Ka. 1 hit.
PANTHER	PTHR10048. PI_Kinase. 1 hit.
Pfam	PF00454. PI3_PI4_kinase. 1 hit. PF00792. PI3K_C2. 1 hit. PF00794. PI3K_rbd. 1 hit. PF00613. PI3Ka. 1 hit. [Graphical view]
SMART	SM00142. PI3K_C2. 1 hit. SM00144. PI3K_rbd. 1 hit. SM00145. PI3Ka. 1 hit. SM00146. PI3Kc. 1 hit. [Graphical view]
PROSITE	PS00915. PI3_4_KINASE_1. 1 hit. PS00916. PI3_4_KINASE_2. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q9EQL1_MOUSE

Accession

Primary (citable) accession number: Q9EQL1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	November 3, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)