Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Chemokine (C-X-C motif) ligand 7, isoform CRA_b

Gene

Ppbp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • CXCR chemokine receptor binding Source: GO_Central

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-114608. Platelet degranulation.
R-MMU-380108. Chemokine receptors bind chemokines.
R-MMU-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-X-C motif) ligand 7, isoform CRA_bImported
Submitted name:
Chemokine subfamily B Cys-X-CysImported
Submitted name:
Platelet basic proteinImported
Submitted name:
Pro-platelet basic proteinImported
Submitted name:
Protein PpbpImported
Submitted name:
Thymus chemokine 1Imported
Gene namesi
Name:PpbpImported
Synonyms:Cxcl7Imported
ORF Names:mCG_1702Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1888712. Ppbp.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3939Sequence analysisAdd
BLAST
Chaini40 – 11374Sequence analysisPRO_5007928749Add
BLAST

PTM databases

PhosphoSiteiQ9EQI5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029372.

Interactioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • CXCR chemokine receptor binding Source: GO_Central

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031319.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 10961SCYInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JG75. Eukaryota.
ENOG4111BTH. LUCA.
GeneTreeiENSGT00530000062901.
HOGENOMiHOG000220915.
HOVERGENiHBG107789.
KOiK10029.
OMAiLYIELCC.
OrthoDBiEOG091G14KZ.
TreeFamiTF333433.

Family and domain databases

InterProiIPR001089. Chemokine_CXC.
IPR001811. Chemokine_IL8-like_dom.
IPR027223. PPBP.
[Graphical view]
PANTHERiPTHR10179. PTHR10179. 1 hit.
PTHR10179:SF52. PTHR10179:SF52. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
PRINTSiPR00437. SMALLCYTKCXC.
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9EQI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFRLRPTSS CTRACPLHNL QILLLLGLIL VALAPLTAGK SDGMDPYIEL
60 70 80 90 100
RCRCTNTISG IPFNSISLVN VYRPGVHCAD VEVIATLKNG QKTCLDPNAP
110
GVKRIVMKIL EGY
Length:113
Mass (Da):12,252
Last modified:March 1, 2001 - v1
Checksum:i66F93D3F7D7862C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105995 Genomic DNA. No translation available.
AF219112 mRNA. Translation: AAG36786.1.
BC127043 mRNA. Translation: AAI27044.1.
BC127044 mRNA. Translation: AAI27045.1.
AF349465 Genomic DNA. Translation: AAK30162.1.
AF278700 mRNA. Translation: AAK69476.1.
AK010273 mRNA. Translation: BAB26811.1.
AB042817 mRNA. Translation: BAB83941.1.
AK157077 mRNA. Translation: BAE33955.1.
AK157141 mRNA. Translation: BAE33977.1.
AK158061 mRNA. Translation: BAE34343.1.
AK171720 mRNA. Translation: BAE42631.1.
CH466617 Genomic DNA. Translation: EDL05308.1.
PIRiJC7800.
RefSeqiNP_076274.1. NM_023785.3.
UniGeneiMm.293614.

Genome annotation databases

EnsembliENSMUST00000031319; ENSMUSP00000031319; ENSMUSG00000029372.
GeneIDi57349.
KEGGimmu:57349.
UCSCiuc008ybh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105995 Genomic DNA. No translation available.
AF219112 mRNA. Translation: AAG36786.1.
BC127043 mRNA. Translation: AAI27044.1.
BC127044 mRNA. Translation: AAI27045.1.
AF349465 Genomic DNA. Translation: AAK30162.1.
AF278700 mRNA. Translation: AAK69476.1.
AK010273 mRNA. Translation: BAB26811.1.
AB042817 mRNA. Translation: BAB83941.1.
AK157077 mRNA. Translation: BAE33955.1.
AK157141 mRNA. Translation: BAE33977.1.
AK158061 mRNA. Translation: BAE34343.1.
AK171720 mRNA. Translation: BAE42631.1.
CH466617 Genomic DNA. Translation: EDL05308.1.
PIRiJC7800.
RefSeqiNP_076274.1. NM_023785.3.
UniGeneiMm.293614.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031319.

PTM databases

PhosphoSiteiQ9EQI5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031319; ENSMUSP00000031319; ENSMUSG00000029372.
GeneIDi57349.
KEGGimmu:57349.
UCSCiuc008ybh.1. mouse.

Organism-specific databases

CTDi5473.
MGIiMGI:1888712. Ppbp.

Phylogenomic databases

eggNOGiENOG410JG75. Eukaryota.
ENOG4111BTH. LUCA.
GeneTreeiENSGT00530000062901.
HOGENOMiHOG000220915.
HOVERGENiHBG107789.
KOiK10029.
OMAiLYIELCC.
OrthoDBiEOG091G14KZ.
TreeFamiTF333433.

Enzyme and pathway databases

ReactomeiR-MMU-114608. Platelet degranulation.
R-MMU-380108. Chemokine receptors bind chemokines.
R-MMU-418594. G alpha (i) signalling events.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029372.

Family and domain databases

InterProiIPR001089. Chemokine_CXC.
IPR001811. Chemokine_IL8-like_dom.
IPR027223. PPBP.
[Graphical view]
PANTHERiPTHR10179. PTHR10179. 1 hit.
PTHR10179:SF52. PTHR10179:SF52. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
PRINTSiPR00437. SMALLCYTKCXC.
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9EQI5_MOUSE
AccessioniPrimary (citable) accession number: Q9EQI5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.