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Protein
Submitted name:

Chemokine (C-X-C motif) ligand 7, isoform CRA_b

Gene

Ppbp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • CXCR chemokine receptor binding Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-114608 Platelet degranulation
R-MMU-380108 Chemokine receptors bind chemokines
R-MMU-418594 G alpha (i) signalling events
R-MMU-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-X-C motif) ligand 7, isoform CRA_bImported
Submitted name:
Chemokine subfamily B Cys-X-CysImported
Submitted name:
Platelet basic proteinImported
Submitted name:
Pro-platelet basic proteinImported
Submitted name:
Thymus chemokine 1Imported
Gene namesi
Name:PpbpImported
Synonyms:Cxcl7Imported
ORF Names:mCG_1702Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1888712 Ppbp

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 39Sequence analysisAdd BLAST39
ChainiPRO_501458935940 – 113Sequence analysisAdd BLAST74

Expressioni

Gene expression databases

BgeeiENSMUSG00000029372

Interactioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • CXCR chemokine receptor binding Source: GO_Central

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031319

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 109SCYInterPro annotationAdd BLAST61

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JG75 Eukaryota
ENOG4111BTH LUCA
GeneTreeiENSGT00530000062901
HOGENOMiHOG000220915
HOVERGENiHBG107789
KOiK10029
OMAiLYIELCC
OrthoDBiEOG091G14KZ
TreeFamiTF333433

Family and domain databases

CDDicd00273 Chemokine_CXC, 1 hit
InterProiView protein in InterPro
IPR001089 Chemokine_CXC
IPR001811 Chemokine_IL8-like_dom
IPR033899 CXC_Chemokine_domain
IPR036048 Interleukin_8-like_sf
PANTHERiPTHR10179 PTHR10179, 1 hit
PfamiView protein in Pfam
PF00048 IL8, 1 hit
PRINTSiPR00437 SMALLCYTKCXC
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit

Sequencei

Sequence statusi: Complete.

Q9EQI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFRLRPTSS CTRACPLHNL QILLLLGLIL VALAPLTAGK SDGMDPYIEL
60 70 80 90 100
RCRCTNTISG IPFNSISLVN VYRPGVHCAD VEVIATLKNG QKTCLDPNAP
110
GVKRIVMKIL EGY
Length:113
Mass (Da):12,252
Last modified:March 1, 2001 - v1
Checksum:i66F93D3F7D7862C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105995 Genomic DNA No translation available.
AF219112 mRNA Translation: AAG36786.1
BC127043 mRNA Translation: AAI27044.1
BC127044 mRNA Translation: AAI27045.1
AF349465 Genomic DNA Translation: AAK30162.1
AF278700 mRNA Translation: AAK69476.1
AK010273 mRNA Translation: BAB26811.1
AB042817 mRNA Translation: BAB83941.1
AK157077 mRNA Translation: BAE33955.1
AK157141 mRNA Translation: BAE33977.1
AK158061 mRNA Translation: BAE34343.1
AK171720 mRNA Translation: BAE42631.1
CH466617 Genomic DNA Translation: EDL05308.1
PIRiJC7800
RefSeqiNP_076274.1, NM_023785.3
UniGeneiMm.293614

Genome annotation databases

EnsembliENSMUST00000031319; ENSMUSP00000031319; ENSMUSG00000029372
GeneIDi57349
KEGGimmu:57349
UCSCiuc008ybh.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9EQI5_MOUSE
AccessioniPrimary (citable) accession number: Q9EQI5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 152 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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