Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ropporin-1-like protein

Gene

Ropn1l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cilium movement Source: MGI
  • flagellated sperm motility Source: MGI
  • regulation of protein phosphorylation Source: MGI
  • sperm capacitation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ropporin-1-like protein
Alternative name(s):
AKAP-associated sperm protein
Gene namesi
Name:Ropn1l
Synonyms:Asp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2182357. Ropn1l.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
  • motile cilium Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003074001 – 230Ropporin-1-like proteinAdd BLAST230

Proteomic databases

PaxDbiQ9EQ00.
PeptideAtlasiQ9EQ00.
PRIDEiQ9EQ00.

PTM databases

iPTMnetiQ9EQ00.
PhosphoSitePlusiQ9EQ00.

Expressioni

Tissue specificityi

Testis-specific. Expression is restricted to germ cells.2 Publications

Developmental stagei

Expressed in testis at least from P5 to P40. Expression increases with sample age.1 Publication

Gene expression databases

BgeeiENSMUSG00000022236.
CleanExiMM_ROPN1L.

Interactioni

Subunit structurei

May interact with AKAP3.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106038.

Structurei

3D structure databases

ProteinModelPortaliQ9EQ00.
SMRiQ9EQ00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 54RIIaAdd BLAST38

Sequence similaritiesi

Belongs to the ropporin family.Curated
Contains 1 RIIa domain.Curated

Phylogenomic databases

eggNOGiENOG410IRZH. Eukaryota.
ENOG410Y08Y. LUCA.
HOGENOMiHOG000006862.
HOVERGENiHBG060390.
InParanoidiQ9EQ00.
OMAiWMKILAL.
PhylomeDBiQ9EQ00.
TreeFamiTF105421.

Family and domain databases

InterProiIPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
[Graphical view]
SUPFAMiSSF47391. SSF47391. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9EQ00-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPLPDTMFCA QQIHIPPELP DILKQFTKAA IRTQPADVLQ WSAGYFSALS
60 70 80 90 100
RGDPLPVKDR IEMPVATQKT DTGLTQGLLK VLHKQCSHKQ YVELADLEKK
110 120 130 140 150
WKNLCLPVEK LRTILELDPC EDKIEWIKFL ALGCSSLGRT LNTAMKNVCE
160 170 180 190 200
ILTSDPEGGP ARIPFETFAY VYQYLSGLDP ELPAVETENY LTSLRLMSES
210 220 230
RKNGMIGLSD FFVEKDNIES LEEKALEAEH
Length:230
Mass (Da):25,942
Last modified:March 1, 2001 - v1
Checksum:iF0832651D7467B9C
GO
Isoform 2 (identifier: Q9EQ00-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     214-217: EKDN → GKKI
     218-230: Missing.

Show »
Length:217
Mass (Da):24,402
Checksum:i0C2F95FA032762D7
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_028747214 – 217EKDN → GKKI in isoform 2. 1 Publication4
Alternative sequenceiVSP_028748218 – 230Missing in isoform 2. 1 PublicationAdd BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305427 mRNA. Translation: AAG40851.1.
BC048680 mRNA. Translation: AAH48680.1.
BC060990 mRNA. Translation: AAH60990.1.
RefSeqiNP_665851.2. NM_145852.2.
UniGeneiMm.436668.

Genome annotation databases

GeneIDi252967.
KEGGimmu:252967.
UCSCiuc007vkg.1. mouse. [Q9EQ00-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305427 mRNA. Translation: AAG40851.1.
BC048680 mRNA. Translation: AAH48680.1.
BC060990 mRNA. Translation: AAH60990.1.
RefSeqiNP_665851.2. NM_145852.2.
UniGeneiMm.436668.

3D structure databases

ProteinModelPortaliQ9EQ00.
SMRiQ9EQ00.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106038.

PTM databases

iPTMnetiQ9EQ00.
PhosphoSitePlusiQ9EQ00.

Proteomic databases

PaxDbiQ9EQ00.
PeptideAtlasiQ9EQ00.
PRIDEiQ9EQ00.

Protocols and materials databases

DNASUi252967.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi252967.
KEGGimmu:252967.
UCSCiuc007vkg.1. mouse. [Q9EQ00-2]

Organism-specific databases

CTDi83853.
MGIiMGI:2182357. Ropn1l.

Phylogenomic databases

eggNOGiENOG410IRZH. Eukaryota.
ENOG410Y08Y. LUCA.
HOGENOMiHOG000006862.
HOVERGENiHBG060390.
InParanoidiQ9EQ00.
OMAiWMKILAL.
PhylomeDBiQ9EQ00.
TreeFamiTF105421.

Miscellaneous databases

PROiQ9EQ00.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022236.
CleanExiMM_ROPN1L.

Family and domain databases

InterProiIPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
[Graphical view]
SUPFAMiSSF47391. SSF47391. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiROP1L_MOUSE
AccessioniPrimary (citable) accession number: Q9EQ00
Secondary accession number(s): Q6P8Z9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.