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Protein
Submitted name:

Solute carrier family 25, member 27, isoform CRA_b

Gene

Slc25a27

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cellular triglyceride homeostasis Source: RGD
  • inner ear development Source: RGD
  • negative regulation of apoptotic process Source: RGD
  • negative regulation of mitochondrial calcium ion concentration Source: RGD
  • negative regulation of mitochondrial membrane potential Source: RGD
  • neuron death Source: RGD
  • positive regulation of cell proliferation Source: RGD
  • regulation of glucose import Source: RGD
  • transport Source: UniProtKB-KW

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 25, member 27, isoform CRA_bImported
Submitted name:
Uncoupling protein UCP-4, isoform aImported
Gene namesi
Name:Slc25a27Imported
Synonyms:Ucp-4Imported, Ucp4Imported
ORF Names:rCG_43627Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620787. Slc25a27.

Subcellular locationi

GO - Cellular componenti

  • apical part of cell Source: RGD
  • integral component of membrane Source: UniProtKB-UniRule
  • mitochondrion Source: GOC
  • neuronal cell body Source: RGD

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati20 – 114SolcarPROSITE-ProRule annotationAdd BLAST95
Repeati124 – 216SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati225 – 316SolcarPROSITE-ProRule annotationAdd BLAST92

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0753. Eukaryota.
ENOG410XRV1. LUCA.
HOVERGENiHBG009528.
KOiK15112.
OrthoDBiEOG091G0BQ7.
TreeFamiTF354328.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q9EPH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFPEEESLQ PLTQRWPRTS KFLLSGCAAT VAELATFPLD LTKTRLQMQG
60 70 80 90 100
EAALAKLGDG AMESAPYRGM MRTALGIVQE EGFLKLWQGV TPAIYRHVVY
110 120 130 140 150
SGGRMVTYEH LREVVFGKSE DEHYPLWKSV IGGMMAGVIG QFLANPTDLV
160 170 180 190 200
KVQMQMEGKR RLEGKPLRFR GVHHAFAKIL AEGGIRGLWA GWIPNIQRAA
210 220 230 240 250
LVNMGDLTTY DTVKHYLVLN TALEDNIATH GLSSLCSGLV ASILGTPADV
260 270 280 290 300
IKSRIMNQPR DKQGRGLLYK SSTDCVIQAV QGEGFLSLYK GFLPSWLRMT
310 320
PWSMVFWLTY EKIRQLSGVS PF
Length:322
Mass (Da):35,838
Last modified:March 1, 2001 - v1
Checksum:i454580DCA80A9F90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ300162 mRNA. Translation: CAC20898.1.
CH473987 Genomic DNA. Translation: EDM18700.1.
CH473987 Genomic DNA. Translation: EDM18701.1.
CH473987 Genomic DNA. Translation: EDM18703.1.
RefSeqiNP_445952.1. NM_053500.1.
UniGeneiRn.163043.

Genome annotation databases

GeneIDi85262.
KEGGirno:85262.
UCSCiRGD:620787. rat.

Similar proteinsi

Entry informationi

Entry nameiQ9EPH7_RAT
AccessioniPrimary (citable) accession number: Q9EPH7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: August 30, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)