Reviewed, UniProtKB/Swiss-Prot Q9EPC5 (RET7_MOUSE)

Names and origin

Protein names

Recommended name:
Retinoid-binding protein 7

Alternative name(s):
Cellular retinoic acid-binding protein 4
Short name=CRABP4
Short name=CRBP4
Cellular retinoic acid-binding protein IV
Short name=CRABP-IV

Gene names

Name:

Rbp7

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	134 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Intracellular transport of retinol By similarity.
Subcellular location	Cytoplasm By similarity.
Tissue specificity	Highly expressed in white adipose tissue and mammary gland.
Domain	Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior By similarity.
Sequence similarities	Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cytoplasm
Ligand	Retinol-binding Vitamin A
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	retinal binding Inferred from electronic annotation. Source: UniProtKB-KW retinol binding Inferred from electronic annotation. Source: UniProtKB-KW transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 134	134	Retinoid-binding protein 7		PRO_0000067404

Sequences

	Sequence		Length	Mass (Da)
	Q9EPC5-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 04D1A591AD7263E6	FASTA	134	15,428
	10 20 30 40 50 60 MPADLSGTWN LLSSDNFEGY MLALGIDFAT RKIAKLLKPQ KVIEQNGDSF TIQTCSSLRN 70 80 90 100 110 120 YLVKFKVGEE FEEDNKGLDN RKCTSLVTWE NDKLTCVQRG EKKNRGWSHW IEGDQLHLEM 130 FCEGQVCKQT FQRA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse." Conforti L., Tarlton A., Mack T.G.A., Mi W., Buckmaster E.A., Wagner D., Perry V.H., Coleman M.P. Proc. Natl. Acad. Sci. U.S.A. 97:11377-11382(2000) [PubMed: 11027338] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. Strain: 129, C57BL/6J and C57BL/Wlds.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Mammary gland.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 59-134. Strain: C57BL/6J. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF260927 Genomic DNA. Translation: AAG38491.1. AF260923 mRNA. Translation: AAG17284.1. BC028432 mRNA. Translation: AAH28432.1. AK003307 mRNA. Translation: BAB22705.1.
IPI	IPI00109763.
RefSeq	NP_071303.1.
UniGene	Mm.46023
3D structure databases
SMR	Q9EPC5. Positions 2-134.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9EPC5.
Proteomic databases
PRIDE	Q9EPC5.
Genome annotation databases
Ensembl	ENSMUST00000030848; ENSMUSP00000030848; ENSMUSG00000028996; Mus musculus. [Genome view]
GeneID	63954.
KEGG	mmu:63954.
UCSC	uc008vwh.1. mouse.
Organism-specific databases
CTD	63954.
MGI	MGI:1890409. Rbp7.
Phylogenomic databases
HOGENOM	HBG714759.
HOVERGEN	HBG005633.
InParanoid	Q9EPC5.
OMA	WENDKLT.
OrthoDB	EOG9MSGHP.
PhylomeDB	Q9EPC5.
Gene expression databases
ArrayExpress	Q9EPC5.
Bgee	Q9EPC5.
CleanEx	MM_RBP7.
Genevestigator	Q9EPC5.
GermOnline	ENSMUSG00000028996. Mus musculus.
Family and domain databases
InterPro	IPR012674. Calycin. IPR011038. Calycin-like. IPR000463. Fatty_acid_bd. IPR000566. Lipocln_cytosolic_FA_bd. [Graphical view]
Gene3D	G3DSA:2.40.128.20. Calycin. 1 hit.
PANTHER	PTHR11955. Fatty_acid_bd. 1 hit.
Pfam	PF00061. Lipocalin. 1 hit. [Graphical view]
PRINTS	PR00178. FATTYACIDBP.
SUPFAM	SSF50814. Calycin. 1 hit.
PROSITE	PS00214. FABP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	319815.
SOURCE	Search...

Entry information

Entry name

RET7_MOUSE

Accession

Primary (citable) accession number: Q9EPC5
Secondary accession number(s): Q9CTK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2002
Last sequence update:	March 1, 2001
Last modified:	March 2, 2010
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)