Q9EMI7 (NMT_AMEPV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative glycylpeptide N-tetradecanoyltransferase
EC=2.3.1.97

Alternative name(s):
Myristoyl-CoA:protein N-myristoyltransferase
Short name=NMT
Peptide N-myristoyltransferase

Gene names

Ordered Locus Names:

AMV219

Organism

Amsacta moorei entomopoxvirus (AmEPV)

Taxonomic identifier

28321 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Poxviridae › Entomopoxvirinae › Betaentomopoxvirus

Virus host

Amsacta [TaxID: 340055]

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Adds a myristoyl group to the N-terminal glycine residue of certain proteins Potential. Ref.2
Catalytic activity	Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
Sequence similarities	Belongs to the NMT family.

Ontologies

Keywords
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	glycylpeptide N-tetradecanoyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 299	299	Putative glycylpeptide N-tetradecanoyltransferase		PRO_0000064249

Sequences

	Sequence		Length	Mass (Da)
	Q9EMI7 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: FCEC2E31D7D06F68	FASTA	299	36,429
	10 20 30 40 50 60 MSYWINKSIC KLNYDSIDNI INTIEPHKPY NNNYCKDNFN IKYLDENNIL DYYSFLYKNY 70 80 90 100 110 120 NYKFNLDTIK WLLLNPFSKK EYNILLYNED KIAGTISGIK KTISLHKKIY DCIHVTFLCI 130 140 150 160 170 180 DKDYRNKYLH YFLIDEIMKN AKKNDIIIAL FNSNIKFNNV KYINEYDTYI TYGNKNLIKK 190 200 210 220 230 240 SDYFNYELLN KKTQDLFFIY TIEEYNYWFN NNHVVVISYN NNFIALLKTN MLINKNIIQI 250 260 270 280 290 FIIMEMYIRN NNIHKNYIPN NTIIYENYKC LKTIKLKSKL ISYIYNYNFN NLSESIYLF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genomic sequence of the Amsacta moorei entomopoxvirus: analysis and comparison with other poxviruses." Bawden A.L., Glassberg K.J., Diggans J., Shaw R., Farmerie W., Moyer R.W. Virology 274:120-139(2000) [PubMed: 10936094] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"N-terminal N-myristoylation of proteins: refinement of the sequence motif and its taxon-specific differences." Maurer-Stroh S., Eisenhaber B., Eisenhaber F. J. Mol. Biol. 317:523-540(2002) [PubMed: 11955007] [Abstract] Cited for: POSSIBLE FUNCTION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF250284 Genomic DNA. Translation: AAG02925.1.
RefSeq	NP_065001.1. NC_002520.1.
3D structure databases
ProteinModelPortal	Q9EMI7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1494809.
Phylogenomic databases
ProtClustDB	CLSP2510363.
Family and domain databases
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR022676. MyristoylCoA_TrFase_N. [Graphical view]
Gene3D	G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
Pfam	PF01233. NMT. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NMT_AMEPV

Accession

Primary (citable) accession number: Q9EMI7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	March 1, 2001
Last modified:	September 21, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program