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Q9E7N7

- VP4A_LNYV3

UniProt

Q9E7N7 - VP4A_LNYV3

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Protein
Phosphoprotein
Gene
P
Organism
Lettuce necrotic yellows virus (isolate 318) (LNYV)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA By similarity.

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Viral RNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoprotein
Short name:
Protein P
Alternative name(s):
Protein 4a
Gene namesi
Name:P
OrganismiLettuce necrotic yellows virus (isolate 318) (LNYV)
Taxonomic identifieri928304 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesMononegaviralesRhabdoviridaeCytorhabdovirus
Virus hostiEmbergeria [TaxID: 43191]
Lactuca sativa (Garden lettuce) [TaxID: 4236]
Reichardia tingitana [TaxID: 43208]
Sonchus hydrophilus [TaxID: 255580]
Sonchus oleraceus (Common sowthistle) [TaxID: 50207]
ProteomesiUP000008592: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300Phosphoprotein
PRO_0000299209Add
BLAST

Post-translational modificationi

Phosphorylated by host kinases By similarity.

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Homotrimer when phosphorylated. This trimer is stabilized by binding to the L protein. Binds soluble protein N, and ribonucleocapsid By similarity.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi231 – 24111
Helixi246 – 2494
Helixi254 – 2607
Helixi263 – 2686
Turni269 – 2713
Helixi277 – 30024

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3T4RX-ray2.00A230-300[»]

Sequencei

Sequence statusi: Complete.

Q9E7N7-1 [UniParc]FASTAAdd to Basket

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MDSESLDFSS ADTVILRSPN AGTNPDGHPD TVECPDFDTD IPKTSDDSSK    50
MDNKGSSSSS KAVKDLLELA AKSQGIVVTD VMQNTAIALH HNLGLDASSL 100
DWFVAGITFA NNSMIMEKMV SAIKELQIEV RNIQVASSGI KGTSEELVSK 150
MKANKNDIVK ELVKTRDSVL SAMGGILSAP EIEQQPVKTV TIGASQGRRK 200
STVVPPIEIN PELESPVLSK TVSTATPEER IRHEKEKLLA DLDWEIGEIA 250
QYTPLIVDFL VPDDILAMAA DGLTPELKEK IQNEIIENHI ALMALEEYSS 300
Length:300
Mass (Da):32,499
Last modified:March 1, 2001 - v1
Checksum:iC64041C7E1E2FBDA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF209035 mRNA. Translation: AAG32648.1.
AJ867584 Genomic RNA. Translation: CAI30422.1.
RefSeqiYP_425088.1. NC_007642.1.

Genome annotation databases

GeneIDi3844365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF209035 mRNA. Translation: AAG32648.1 .
AJ867584 Genomic RNA. Translation: CAI30422.1 .
RefSeqi YP_425088.1. NC_007642.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3T4R X-ray 2.00 A 230-300 [» ]
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3844365.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus."
    Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L.
    Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA].

Entry informationi

Entry nameiVP4A_LNYV3
AccessioniPrimary (citable) accession number: Q9E7N7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3

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