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Q9E7N7

- VP4A_LNYV3

UniProt

Q9E7N7 - VP4A_LNYV3

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Protein

Phosphoprotein

Gene

P

Organism
Lettuce necrotic yellows virus (isolate 318) (LNYV)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).By similarity

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Viral RNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoprotein
Short name:
Protein P
Alternative name(s):
Protein 4a
Gene namesi
Name:P
OrganismiLettuce necrotic yellows virus (isolate 318) (LNYV)
Taxonomic identifieri928304 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesMononegaviralesRhabdoviridaeCytorhabdovirus
Virus hostiEmbergeria [TaxID: 43191]
Lactuca sativa (Garden lettuce) [TaxID: 4236]
Reichardia tingitana [TaxID: 43208]
Sonchus hydrophilus [TaxID: 255580]
Sonchus oleraceus (Common sowthistle) [TaxID: 50207]
ProteomesiUP000008592: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-KW
  2. virion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300PhosphoproteinPRO_0000299209Add
BLAST

Post-translational modificationi

Phosphorylated by host kinases.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Homotrimer when phosphorylated. This trimer is stabilized by binding to the L protein. Binds soluble protein N, and ribonucleocapsid (By similarity).By similarity

Structurei

Secondary structure

1
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi231 – 24111Combined sources
Helixi246 – 2494Combined sources
Helixi254 – 2607Combined sources
Helixi263 – 2686Combined sources
Turni269 – 2713Combined sources
Helixi277 – 30024Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3T4RX-ray2.00A230-300[»]
ModBaseiSearch...
MobiDBiSearch...

Sequencei

Sequence statusi: Complete.

Q9E7N7-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDSESLDFSS ADTVILRSPN AGTNPDGHPD TVECPDFDTD IPKTSDDSSK
60 70 80 90 100
MDNKGSSSSS KAVKDLLELA AKSQGIVVTD VMQNTAIALH HNLGLDASSL
110 120 130 140 150
DWFVAGITFA NNSMIMEKMV SAIKELQIEV RNIQVASSGI KGTSEELVSK
160 170 180 190 200
MKANKNDIVK ELVKTRDSVL SAMGGILSAP EIEQQPVKTV TIGASQGRRK
210 220 230 240 250
STVVPPIEIN PELESPVLSK TVSTATPEER IRHEKEKLLA DLDWEIGEIA
260 270 280 290 300
QYTPLIVDFL VPDDILAMAA DGLTPELKEK IQNEIIENHI ALMALEEYSS
Length:300
Mass (Da):32,499
Last modified:March 1, 2001 - v1
Checksum:iC64041C7E1E2FBDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF209035 mRNA. Translation: AAG32648.1.
AJ867584 Genomic RNA. Translation: CAI30422.1.
RefSeqiYP_425088.1. NC_007642.1.

Genome annotation databases

GeneIDi3844365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF209035 mRNA. Translation: AAG32648.1 .
AJ867584 Genomic RNA. Translation: CAI30422.1 .
RefSeqi YP_425088.1. NC_007642.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3T4R X-ray 2.00 A 230-300 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3844365.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus."
    Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L.
    Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA].

Entry informationi

Entry nameiVP4A_LNYV3
AccessioniPrimary (citable) accession number: Q9E7N7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: November 26, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3