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Q9E7N7

- VP4A_LNYV3

UniProt

Q9E7N7 - VP4A_LNYV3

Protein

Phosphoprotein

Gene

P

Organism
Lettuce necrotic yellows virus (isolate 318) (LNYV)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA By similarity.By similarity

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Viral RNA replication

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoprotein
    Short name:
    Protein P
    Alternative name(s):
    Protein 4a
    Gene namesi
    Name:P
    OrganismiLettuce necrotic yellows virus (isolate 318) (LNYV)
    Taxonomic identifieri928304 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesMononegaviralesRhabdoviridaeCytorhabdovirus
    Virus hostiEmbergeria [TaxID: 43191]
    Lactuca sativa (Garden lettuce) [TaxID: 4236]
    Reichardia tingitana [TaxID: 43208]
    Sonchus hydrophilus [TaxID: 255580]
    Sonchus oleraceus (Common sowthistle) [TaxID: 50207]
    ProteomesiUP000008592: Genome

    Subcellular locationi

    Virion. Host cytoplasm By similarity

    GO - Cellular componenti

    1. host cell cytoplasm Source: UniProtKB-SubCell
    2. virion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Host cytoplasm, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 300300PhosphoproteinPRO_0000299209Add
    BLAST

    Post-translational modificationi

    Phosphorylated by host kinases.By similarity

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Subunit structurei

    Homotrimer when phosphorylated. This trimer is stabilized by binding to the L protein. Binds soluble protein N, and ribonucleocapsid By similarity.By similarity

    Structurei

    Secondary structure

    1
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi231 – 24111
    Helixi246 – 2494
    Helixi254 – 2607
    Helixi263 – 2686
    Turni269 – 2713
    Helixi277 – 30024

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3T4RX-ray2.00A230-300[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Sequencei

    Sequence statusi: Complete.

    Q9E7N7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSESLDFSS ADTVILRSPN AGTNPDGHPD TVECPDFDTD IPKTSDDSSK    50
    MDNKGSSSSS KAVKDLLELA AKSQGIVVTD VMQNTAIALH HNLGLDASSL 100
    DWFVAGITFA NNSMIMEKMV SAIKELQIEV RNIQVASSGI KGTSEELVSK 150
    MKANKNDIVK ELVKTRDSVL SAMGGILSAP EIEQQPVKTV TIGASQGRRK 200
    STVVPPIEIN PELESPVLSK TVSTATPEER IRHEKEKLLA DLDWEIGEIA 250
    QYTPLIVDFL VPDDILAMAA DGLTPELKEK IQNEIIENHI ALMALEEYSS 300
    Length:300
    Mass (Da):32,499
    Last modified:March 1, 2001 - v1
    Checksum:iC64041C7E1E2FBDA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF209035 mRNA. Translation: AAG32648.1.
    AJ867584 Genomic RNA. Translation: CAI30422.1.
    RefSeqiYP_425088.1. NC_007642.1.

    Genome annotation databases

    GeneIDi3844365.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF209035 mRNA. Translation: AAG32648.1 .
    AJ867584 Genomic RNA. Translation: CAI30422.1 .
    RefSeqi YP_425088.1. NC_007642.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3T4R X-ray 2.00 A 230-300 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3844365.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus."
      Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L.
      Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA].

    Entry informationi

    Entry nameiVP4A_LNYV3
    AccessioniPrimary (citable) accession number: Q9E7N7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3