Q9E7N7 (VP4A_LNYV3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoprotein
Short name=Protein P

Alternative name(s):
Protein 4a

Gene names

Name:

P

Organism

Lettuce necrotic yellows virus (isolate 318) (LNYV) [Reference proteome]

Taxonomic identifier

928304 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Mononegavirales › Rhabdoviridae › Cytorhabdovirus › Lettuce necrotic yellows virus

Virus host

Embergeria [TaxID: 43191]
Lactuca sativa (Garden lettuce) [TaxID: 4236]
Reichardia tingitana [TaxID: 43208]
Sonchus hydrophilus [TaxID: 255580]
Sonchus oleraceus (Common sowthistle) [TaxID: 50207]

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA By similarity.
Subunit structure	Homotrimer when phosphorylated. This trimer is stabilized by binding to the L protein. Binds soluble protein N, and ribonucleocapsid By similarity.
Subcellular location	Virion. Host cytoplasm By similarity.
Post-translational modification	Phosphorylated by host kinases By similarity.

Ontologies

Keywords
Biological process	Viral RNA replication
Cellular component	Host cytoplasm Virion
Molecular function	Chaperone
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	host cell cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 300

300

Phosphoprotein

PRO_0000299209

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

300

Helix Strand Turn

Details...

Helix

231 – 241

11

Helix

246 – 249

4

Helix

254 – 260

7

Helix

263 – 268

6

Turn

269 – 271

3

Helix

277 – 300

24

Sequences

	Sequence		Length	Mass (Da)
	Q9E7N7 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: C64041C7E1E2FBDA	FASTA	300	32,499
	10 20 30 40 50 60 MDSESLDFSS ADTVILRSPN AGTNPDGHPD TVECPDFDTD IPKTSDDSSK MDNKGSSSSS 70 80 90 100 110 120 KAVKDLLELA AKSQGIVVTD VMQNTAIALH HNLGLDASSL DWFVAGITFA NNSMIMEKMV 130 140 150 160 170 180 SAIKELQIEV RNIQVASSGI KGTSEELVSK MKANKNDIVK ELVKTRDSVL SAMGGILSAP 190 200 210 220 230 240 EIEQQPVKTV TIGASQGRRK STVVPPIEIN PELESPVLSK TVSTATPEER IRHEKEKLLA 250 260 270 280 290 300 DLDWEIGEIA QYTPLIVDFL VPDDILAMAA DGLTPELKEK IQNEIIENHI ALMALEEYSS

References

[1]	"Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus." Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L. Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF209035 mRNA. Translation: AAG32648.1.
AJ867584 Genomic RNA. Translation: CAI30422.1.

RefSeq

YP_425088.1. NC_007642.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3T4R	X-ray	2.00	A	230-300	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3844365.

Family and domain databases

ProtoNet

Search...

Entry information

Entry name

VP4A_LNYV3

Accession

Primary (citable) accession number: Q9E7N7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program