Unreviewed, UniProtKB/TrEMBL Q9E7N1 (Q9E7N1_PI2H)

Names and origin

Protein names	Submitted name:     Hemagglutinin-neuraminidase glycoprotein EMBL AAG10684.1
Organism	Human parainfluenza 2 virus (HPIV-2) EMBL AAG10684.1
Taxonomic identifier	11212 [NCBI]
Taxonomic lineage	Viruses › ssRNA negative-strand viruses › Mononegavirales › Paramyxoviridae › Paramyxovirinae › Rubulavirus
Virus host	Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	571 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. RuleBase RU004216V0

Ontologies

Keywords
Cellular component	Envelope protein RuleBase RU004216V0 Spearmint SPM000665 Membrane Virion
Domain	Transmembrane Spearmint SPM000665
Molecular function	Hemagglutinin RuleBase RU004216V0 Spearmint SPM000665
Gene Ontology (GO)
Biological process	viral infectious cycle Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW viral envelope Inferred from electronic annotation. Source: InterPro
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro host cell surface receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9E7N1-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 5A1B32A0ABDCF13B	FASTA	571	63,393
	10 20 30 40 50 60 MEDYSNLSLK SIPKRTCRII FRTATILGIC TLIVLCSSIL HEIIHLDVSS GLMNSDESQQ 70 80 90 100 110 120 GIIQPIIESL KSLIALANQI LYNVAIVIPL KIDSIETVIL SALKDMHTGS MSNANCTPGN 130 140 150 160 170 180 LLLHDATYIN GINKFLVLES YNGTPKYGPL LNIPSFIPSA TSPHGCTRIP SFSLIKTHWC 190 200 210 220 230 240 YTHNVMLGDC LDFTASNQYL SMGIIQQSAA GFPIFRTMKT IYLSDGINRK SCSVTAIPGG 250 260 270 280 290 300 CVLYCYVATR SEKEDYATTD LAELRLAFYY YNDTFIERVI SLPNTTGQWA TINPAVGSGI 310 320 330 340 350 360 YHLGFILFPV YGGLINGTTS YNEQSSRYFI PKHPNITCAG NSSKQAAIAR SSYVIRYHSN 370 380 390 400 410 420 RLIQSAVLIC PLSDMHTEEC NLVMFNNSQV MMGAEGRLYV IGNNLYYYQR SSSWWSASLF 430 440 450 460 470 480 YRINTDFSKG IPPIIEAQWV PSYQVPRPGV MPCNATSFCP ANCITGVYAD VWPLNDPELM 490 500 510 520 530 540 SRNALNPNYR FAGAFLKNES NRTNPTFYTA SANSLLNTTG FNNTNHKAAY TSSTCFKNTG 550 560 570 TQKIYCLIII EMGSSLLGEF QIIPFLRELM L

References

[1]

"Replacement of the ectodomains of the hemagglutinin-neuraminidase and fusion glycoproteins of recombinant parainfluenza virus type 3 (PIV3) with their counterparts from PIV2 yields attenuated PIV2 vaccine candidates." Tao T., Skiadopoulos M.H., Davoodi F., Riggs J.M., Collins P.L., Murphy B.R. J. Virol. 74:6448-6458(2000) [PubMed: 10864657] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PIV2/V9412-6 EMBL AAG10684.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF213352 mRNA. Translation: AAG10684.1.
3D structure databases
HSSP	HSSP built from PDB template 1USR based on UniProtKB P32884.
ModBase	Search...
Protein family/group databases
CAZy	GH83. Glycoside Hydrolase Family 83.
Family and domain databases
InterPro	IPR000665. Hemagglutn-neuramid_glycoprot. IPR016285. Hemagglutn-neuramid_paramyxo. [Graphical view]
Pfam	PF00423. HN. 1 hit. [Graphical view]
PIRSF	PIRSF001072. Hemagglut-neuramid_paramyxoV. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9E7N1_PI2H

Accession

Primary (citable) accession number: Q9E7N1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 5, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)