Q9DUN1 (Q9DUN1_HHV8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Interferon regulatory factor 3 EMBL AAF23608.2

Submitted name:
VIRF-3 protein EMBL ADQ57941.1

Gene names

Name:

vIRF-3 EMBL AAF23608.2

Organism

Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus) EMBL AAF23608.2

Taxonomic identifier

37296 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Gammaherpesvirinae › Rhadinovirus

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct regulatory region DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9DUN1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 822C557407A8C84B	FASTA	566	62,508
	10 20 30 40 50 60 MAGRRLTWIS EFIVGALDSD KYPLVKWLDR STGTFLAPAA RNDVIPLDSL QFFIDFKREC 70 80 90 100 110 120 LSKGLHPRDL LGSPITAFGK ICTTSRRLRR LPGEEYEVVQ GINCRRWRLL CAEVKECWWC 130 140 150 160 170 180 VHARTHLHSG SSLWEILYQH SVRLEKHRRR PRPFVGENSD SSEEDHPAFC DVPVTQTGAE 190 200 210 220 230 240 SEDSGDEGPS TRHSASGVQP VDDANADSPG SGDEGPSTRH SDSQPPPADE TTVHTDNVED 250 260 270 280 290 300 DLTLLDKESA CALMYHVGQE MDMLMRAMCD EDLFDLLGIP EDVIATSQPG GDTDASGVVT 310 320 330 340 350 360 EGSIAASAVG AGVEDVYLAG ALEAQNVAGE YVLEISDEEV DDGAGLPPAS RRRPVVGEFL 370 380 390 400 410 420 WDDGPRRHER PTTRRIRHRK LRSAYYRVAR PPVMITDRLG VEVFYFGRPA MSLEVERKVF 430 440 450 460 470 480 ILCSQNPLAD ISHSCLHSRK GLRVLLPKPD DNNTGPGDVN LLAAVLRSFA SGLVIVSLRS 490 500 510 520 530 540 GIYVKNLCKS TVLYHGNNPP KKFGVICGLS SRAVLDVFNV AQYRIQGHEH IKKTTVFIGG 550 560 DPTSAEQFDM VPLVIKLRLR SVTCDD

References

[1]

"Characterization of a novel human herpesvirus 8-encoded protein, vIRF-3, that shows homology to viral and cellular interferon regulatory factors." Lubyova B., Pitha P.M. J. Virol. 74:8194-8201(2000) [PubMed: 10933732] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

[2]

"Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Contains a Duplication of a Long Unique-Region Fragment within the Terminal Repeat Region." Yakushko Y., Hackmann C., Gunther T., Ruckert J., Henke M., Koste L., Alkharsah K., Bohne J., Grundhoff A., Schulz T.F., Henke-Gendo C. J. Virol. 85:4612-4617(2011) [PubMed: 21307197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: KSHV-BAC36 EMBL ADQ57941.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF157602 mRNA. Translation: AAF23608.2. HQ404500 Genomic DNA. Translation: ADQ57941.1.
RefSeq	YP_001129413.1. NC_009333.1.
3D structure databases
ProteinModelPortal	Q9DUN1.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9DUN1. 2 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4961493.
Phylogenomic databases
ProtClustDB	CLSP2744203.
Family and domain databases
InterPro	IPR001346. Interferon_reg_fact_DNA-bd_dom. IPR019471. Interferon_reg_factor-3. IPR017855. SMAD_dom-like. IPR008984. SMAD_FHA_domain. [Graphical view]
Gene3D	G3DSA:2.60.200.10. MH2_Dwarfin-type. 1 hit.
Pfam	PF10401. IRF-3. 1 hit. [Graphical view]
SUPFAM	SSF49879. SMAD_FHA. 1 hit.
PROSITE	PS51507. IRF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9DUN1_HHV8

Accession

Primary (citable) accession number: Q9DUN1
Secondary accession number(s): Q2HR72

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)