ID   POLS_ABPVR              Reviewed;         904 AA.
AC   Q9DSN8;
DT   24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2013, sequence version 2.
DT   13-SEP-2023, entry version 65.
DE   RecName: Full=Structural polyprotein;
DE   Contains:
DE     RecName: Full=Protein VP1;
DE     AltName: Full=Virion protein 2;
DE   Contains:
DE     RecName: Full=Protein VP4;
DE     AltName: Full=Virion protein 4;
DE   Contains:
DE     RecName: Full=Protein VP2;
DE     AltName: Full=Virion protein 3;
DE   Contains:
DE     RecName: Full=Protein VP3;
DE     AltName: Full=Virion protein 1;
GN   ORFNames=ORF2;
OS   Acute bee paralysis virus (strain Rothamsted) (ABPV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Dicistroviridae; Aparavirus; Aparavirus apisacutum.
OX   NCBI_TaxID=1217067;
OH   NCBI_TaxID=7460; Apis mellifera (Honeybee).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=11080493; DOI=10.1006/viro.2000.0616;
RA   Govan V.A., Leat N., Allsopp M., Davison S.;
RT   "Analysis of the complete genome sequence of acute bee paralysis virus
RT   shows that it belongs to the novel group of insect-infecting RNA viruses.";
RL   Virology 277:457-463(2000).
RN   [2]
RP   PROTEOLYTIC PROCESSING OF POLYPROTEIN.
RX   PubMed=22258854; DOI=10.1007/s00705-012-1223-0;
RA   Azzami K., Ritter W., Tautz J., Beier H.;
RT   "Infection of honey bees with acute bee paralysis virus does not trigger
RT   humoral or cellular immune responses.";
RL   Arch. Virol. 157:689-702(2012).
CC   -!- FUNCTION: Structural polyprotein: precursor of all the viral capsid
CC       proteins.
CC   -!- FUNCTION: [Protein VP1]: Forms, together with protein VP2 and protein
CC       VP3, an icosahedral capsid protecting the viral RNA genome. The
CC       icosahedral capsid has a pseudo-T=3 symmetry with a diameter of
CC       approximately 300 Angstroms, and is composed of 60 copies of each
CC       capsid proteins.
CC   -!- FUNCTION: [Protein VP2]: Forms, together with protein VP1 and protein
CC       VP3, an icosahedral capsid protecting the viral RNA genome. The
CC       icosahedral capsid has a pseudo-T=3 symmetry with a diameter of
CC       approximately 300 Angstroms, and is composed of 60 copies of each
CC       capsid proteins.
CC   -!- FUNCTION: [Protein VP3]: Forms, together with protein VP1 and protein
CC       VP2, an icosahedral capsid protecting the viral RNA genome. The
CC       icosahedral capsid has a pseudo-T=3 symmetry with a diameter of
CC       approximately 300 Angstroms, and is composed of 60 copies of each
CC       capsid proteins.
CC   -!- SUBCELLULAR LOCATION: [Protein VP1]: Virion. Host cytoplasm
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: [Protein VP2]: Virion. Host cytoplasm
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: [Protein VP3]: Virion. Host cytoplasm
CC       {ECO:0000305}.
CC   -!- PTM: Specific enzymatic cleavages in vivo yield mature proteins.
CC       {ECO:0000269|PubMed:22258854}.
CC   -!- SIMILARITY: Belongs to the picornaviruses polyprotein family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Translation initiates on an Ala codon through an unusual
CC       Internal Ribosome Entry Site (IRES). {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG13119.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF150629; AAG13119.1; ALT_INIT; Genomic_RNA.
DR   RefSeq; NP_066242.1; NC_002548.1.
DR   SMR; Q9DSN8; -.
DR   GeneID; 911836; -.
DR   KEGG; vg:911836; -.
DR   Proteomes; UP000006040; Segment.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   CDD; cd00205; rhv_like; 2.
DR   Gene3D; 2.60.120.20; -; 3.
DR   InterPro; IPR014872; Dicistrovirus_capsid-polyPr_C.
DR   InterPro; IPR001676; Picornavirus_capsid.
DR   InterPro; IPR033703; Rhv-like.
DR   InterPro; IPR029053; Viral_coat.
DR   InterPro; IPR024343; VP4_dicistrovir.
DR   Pfam; PF08762; CRPV_capsid; 1.
DR   Pfam; PF11492; Dicistro_VP4; 1.
DR   Pfam; PF00073; Rhv; 1.
DR   SUPFAM; SSF88633; Positive stranded ssRNA viruses; 3.
PE   1: Evidence at protein level;
KW   Capsid protein; Host cytoplasm; Reference proteome; Virion.
FT   CHAIN           1..314
FT                   /note="Protein VP1"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000423154"
FT   CHAIN           315..396
FT                   /note="Protein VP4"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000423155"
FT   CHAIN           397..696
FT                   /note="Protein VP2"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000423156"
FT   CHAIN           697..904
FT                   /note="Protein VP3"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000423157"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          35..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          320..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   904 AA;  100879 MW;  F9AA1FF575432CCE CRC64;
     ADQETNTSNV HNTQLASTSE ENSVETEQIT TFHDVETPNR INTPMAQDTS SARSMDDTHS
     IIQFLQRPVL IDHIEVIAGS TADDNKPLNR YVLNRQNPQP FVKSWTLPSV VLSAGGKGQK
     LANFKYLRCD VKVKIVLNAN PFIAGRLYLA YSPYDDRVDP ARSILNTSRA GVTGYPGIEI
     DFQLDNSVEM TIPYASFQEA YDLVTGTEDF VKLYLFTITP ILSPTSTSAS SKVDLSVYMW
     LDNISLVIPT YRVNTSIVPN VGTVVQTVQN MTTRDSETIR KAMVALRKNN KSTYDYIVQA
     LSSAVPEVKN VTMQINSKKN NSNKMATPVK EKTKNIPKPK TENPKIGPIS ELATGVNKVA
     NGIERIPVIG EMAKPVTSTI KWVADKIGSV AAIFGWSKPR NLEQVNLYQN VPGWGYSLYK
     GIDNSVPLAF DPNNELGDLR DVFPSGVDEM AIGYVCGNPA VKHVLSWNTT DKVQAPISNG
     DDWGGVIPVG MPCYSKIIRT TENDTTRTNT EIMDPAPCEY VCNMFSYWRA TMCYRIAIVK
     TAFHTGRLGI FFGPGKIPIT TTKDNISPDL TQLDGIKAPS DNNYKYILDL TNDTEITIRV
     PFVSNKMFMK STGIYGGNSE NNWDFSESFT GFLCIRPITK FMCPETVSNN VSIVVWKWAE
     DVVVVEPKPL LSGPTQVFQP PVTSADSINT IDASMQINLA NKADENVVTF FDSDDAEERN
     MEALLKGSGE QIMNLRSLLR TFRTISENWN LPPNTKTAIT DLTDVADKEG RDYMSYLSYI
     YRFYRGGRRY KFFNTTALKQ SQTCYVRSFL IPRYYTADNT NNDGPSHITY PVLNPVHEVE
     VPYYCQYRKL PVASTTDKGY DASLMYYSNV GTNQIVARAG NDDFTFGWLI GTPQTQGITR
     TETK
//