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Q9DIC6

- VGLG_LNYV3

UniProt

Q9DIC6 - VGLG_LNYV3

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Protein

Glycoprotein G

Gene

G

Organism
Lettuce necrotic yellows virus (isolate 318) (LNYV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane By similarity.By similarity

GO - Biological processi

  1. viral entry into host cell Source: UniProtKB-KW
  2. virion attachment to host cell Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Viral attachment to host cell, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Glycoprotein G
Gene namesi
Name:G
OrganismiLettuce necrotic yellows virus (isolate 318) (LNYV)
Taxonomic identifieri928304 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesMononegaviralesRhabdoviridaeCytorhabdovirus
Virus hostiEmbergeria [TaxID: 43191]
Lactuca sativa (Garden lettuce) [TaxID: 4236]
Reichardia tingitana [TaxID: 43208]
Sonchus hydrophilus [TaxID: 255580]
Sonchus oleraceus (Common sowthistle) [TaxID: 50207]
ProteomesiUP000008592: Genome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. viral envelope Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Viral envelope protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 551526Glycoprotein GPRO_5000065805Add
BLAST

Post-translational modificationi

Glycosylated by host. Glycosylation is crucial for glycoprotein export at the cell surface By similarity.By similarity

Keywords - PTMi

Glycoprotein

Interactioni

Subunit structurei

Homotrimer. Interacts with matrix protein By similarity.By similarity

Structurei

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini26 – 503478Virion surfaceSequence AnalysisAdd
BLAST
Topological domaini525 – 55127IntravirionSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei504 – 52421HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9DIC6-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MVSKITLLCF AITCDVLISM GTVQGVFNHS VGPLAVCSPD MEDARAYTEN
60 70 80 90 100
CYRRCSRNKE PSTHGYVWLY SDTAPKGGPV VTRCNKVRVK QVFTETWSFS
110 120 130 140 150
FIKGTPTRMT LDVTEAECVA VMRSQCPTHN CNIKAPSELP EEYHYASDTE
160 170 180 190 200
VVQDYLEILS MPSGLDYMEE NLRITPSQSK FSFQLTDGKG QEGQYIYFWD
210 220 230 240 250
TKYDDTKCPF DSFQSHGCDK YDSPLDLINC RESRFVIPSI ANSTTLVGAC
260 270 280 290 300
QGLQKSTTGL IYKWDDRPDS IANDSKRIAL TKNDQTAGNV ATLRVLVADS
310 320 330 340 350
LNAVDEDLCH TQCEMLDFIL RSDRKREVLT RIGGSYLVVS KTSYIRQCRP
360 370 380 390 400
LVGCRIVKPH YFCGNPNRVA IICHGKVWYW DPLKSYVDEG MNCERRVAGT
410 420 430 440 450
KLVFAVGNHE YAIDDDMHVE LPEHETYGIS HDLLASSEDR ISKDIVDPTE
460 470 480 490 500
LRNSWQSHIA KEGRMSIEPL SQDKQVSHWD AEFSNPLTWL TSAGGWILDM
510 520 530 540 550
SHKVTLWATV FLTLGALVAG AKVWEIMRKA NRKSQYKRTN TEPHDSQATW

I
Length:551
Mass (Da):62,317
Last modified:March 1, 2001 - v1
Checksum:i838FA34080A37F98
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251533 Genomic RNA. Translation: CAC18651.1.
AJ867584 Genomic RNA. Translation: CAI30425.1.
RefSeqiYP_425091.1. NC_007642.1.

Genome annotation databases

GeneIDi3844361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251533 Genomic RNA. Translation: CAC18651.1 .
AJ867584 Genomic RNA. Translation: CAI30425.1 .
RefSeqi YP_425091.1. NC_007642.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3844361.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus."
    Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L.
    Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVGLG_LNYV3
AccessioniPrimary (citable) accession number: Q9DIC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3