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Q9DIC6

- VGLG_LNYV3

UniProt

Q9DIC6 - VGLG_LNYV3

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Protein

Glycoprotein G

Gene
G
Organism
Lettuce necrotic yellows virus (isolate 318) (LNYV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane By similarity.

GO - Biological processi

  1. viral entry into host cell Source: UniProtKB-KW
  2. virion attachment to host cell Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Viral attachment to host cell, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Glycoprotein G
Gene namesi
Name:G
OrganismiLettuce necrotic yellows virus (isolate 318) (LNYV)
Taxonomic identifieri928304 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesMononegaviralesRhabdoviridaeCytorhabdovirus
Virus hostiEmbergeria [TaxID: 43191]
Lactuca sativa (Garden lettuce) [TaxID: 4236]
Reichardia tingitana [TaxID: 43208]
Sonchus hydrophilus [TaxID: 255580]
Sonchus oleraceus (Common sowthistle) [TaxID: 50207]
ProteomesiUP000008592: Genome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini26 – 503478Virion surface Reviewed predictionAdd
BLAST
Transmembranei504 – 52421Helical; Reviewed predictionAdd
BLAST
Topological domaini525 – 55127Intravirion Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. viral envelope Source: UniProtKB-KW
  3. virion membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Viral envelope protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525 Reviewed predictionAdd
BLAST
Chaini26 – 551526Glycoprotein GPRO_5000065805Add
BLAST

Post-translational modificationi

Glycosylated by host. Glycosylation is crucial for glycoprotein export at the cell surface By similarity.

Keywords - PTMi

Glycoprotein

Interactioni

Subunit structurei

Homotrimer. Interacts with matrix protein By similarity.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9DIC6-1 [UniParc]FASTAAdd to Basket

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MVSKITLLCF AITCDVLISM GTVQGVFNHS VGPLAVCSPD MEDARAYTEN    50
CYRRCSRNKE PSTHGYVWLY SDTAPKGGPV VTRCNKVRVK QVFTETWSFS 100
FIKGTPTRMT LDVTEAECVA VMRSQCPTHN CNIKAPSELP EEYHYASDTE 150
VVQDYLEILS MPSGLDYMEE NLRITPSQSK FSFQLTDGKG QEGQYIYFWD 200
TKYDDTKCPF DSFQSHGCDK YDSPLDLINC RESRFVIPSI ANSTTLVGAC 250
QGLQKSTTGL IYKWDDRPDS IANDSKRIAL TKNDQTAGNV ATLRVLVADS 300
LNAVDEDLCH TQCEMLDFIL RSDRKREVLT RIGGSYLVVS KTSYIRQCRP 350
LVGCRIVKPH YFCGNPNRVA IICHGKVWYW DPLKSYVDEG MNCERRVAGT 400
KLVFAVGNHE YAIDDDMHVE LPEHETYGIS HDLLASSEDR ISKDIVDPTE 450
LRNSWQSHIA KEGRMSIEPL SQDKQVSHWD AEFSNPLTWL TSAGGWILDM 500
SHKVTLWATV FLTLGALVAG AKVWEIMRKA NRKSQYKRTN TEPHDSQATW 550
I 551
Length:551
Mass (Da):62,317
Last modified:March 1, 2001 - v1
Checksum:i838FA34080A37F98
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251533 Genomic RNA. Translation: CAC18651.1.
AJ867584 Genomic RNA. Translation: CAI30425.1.
RefSeqiYP_425091.1. NC_007642.1.

Genome annotation databases

GeneIDi3844361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251533 Genomic RNA. Translation: CAC18651.1 .
AJ867584 Genomic RNA. Translation: CAI30425.1 .
RefSeqi YP_425091.1. NC_007642.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3844361.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Lettuce necrotic yellows virus, type species of the genus Cytorhabdovirus."
    Dietzgen R.G., Callaghan B., Wetzel T., Dale J.L.
    Virus Res. 118:16-22(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVGLG_LNYV3
AccessioniPrimary (citable) accession number: Q9DIC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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