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Q9DIC5 (RDRP_AHNNV) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase

Short name=RdRp
EC=2.7.7.48
Alternative name(s):
RNA replicase
Short name=Protein A
OrganismAtlantic halibut nervous necrosis virus (AhNNV)
Taxonomic identifier99486 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeBetanodavirus
Virus hostHippoglossus hippoglossus (Atlantic halibut) (Pleuronectes hippoglossus) [TaxID: 8267]

Protein attributes

Sequence length981 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Potential.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sequence similarities

Belongs to the nodaviridae RNA polymerase family.

Contains 1 RdRp catalytic domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 981981RNA-directed RNA polymerase
PRO_0000222443

Regions

Domain579 – 701123RdRp catalytic

Sequences

Sequence LengthMass (Da)Tools
Q9DIC5 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 6587D72D676FEA50

FASTA981110,328
        10         20         30         40         50         60 
MRSYEFHLAR MSGATLCVVT GYRLLTSKWL ADRIEDYRQR VIADRKKIIR DAAMIRTSVQ 

        70         80         90        100        110        120 
KQMELVRISV RKGHSHQEAA TERNSATETM LSVVEKSGYE PYIISPSPRE AEYHGSRQFY 

       130        140        150        160        170        180 
SLADFRQDYR RDEITDRHII VMTDVDYYVD MNELIGLGVP VLMYTFQPST VSGEVKDGYF 

       190        200        210        220        230        240 
TITDDSVHYR VAGGKDVRHR IWNYNQDTMY TVSRPTGFWE NLKRILRDIT GITALCGFLY 

       250        260        270        280        290        300 
NKLGMAPFGD PVTMFTVDQF KMGEHRNIVS IVPFATCRSN LLKISEYGAE LEYMRYQQRN 

       310        320        330        340        350        360 
NIANFNAVTY ISEEGPLISL GLEGNFASVQ LPLQDFENVR TAYELSKTNN LSDTVRRSGR 

       370        380        390        400        410        420 
PCKEAAIIHK CLQAECVLAS EVVHKPGDLA RHYQAVGSLY DVDPAEQGKC YAREYAPGPL 

       430        440        450        460        470        480 
TQTAVFPNES RSNERATIDG RIAGPQAKAK SREHITPRMR KVARDFVRHL VPEAGLGRPY 

       490        500        510        520        530        540 
PLTYVEEQQS KPLQRARNDA NRYHDEFTMI VKAFQKKEAY NAPNYPRNIS TVPHNQNVKL 

       550        560        570        580        590        600 
SSYTYAFKAS TLQHVPWYMP THTPAEIADA VQNLAASTTE LVETDYSKFD GTFLRFMREC 

       610        620        630        640        650        660 
VEFAIYKRWV HLDHLAELSQ LLANELQAPA VTRLGLKYDP DCSRLSGSAL TTDGNSIANA 

       670        680        690        700        710        720 
FVSYLANRLA GMDDDEAWSW IGIVYGDDGL RSGNVSDTLL TDTASSLGFD LKIVNRAPRG 

       730        740        750        760        770        780 
SPVTFLARVY LDPWSSPASV QSPFRTLLKL HTTCDTQSEI EDIGWAKTQA YLVTDCKTPF 

       790        800        810        820        830        840 
IGHWCRAYQR NCTARVVQYA DYNDIPFWVK NDDHLGNSWP QSDSVDWNDV VANELGLTTA 

       850        860        870        880        890        900 
ELLKHIALLE AYTGPTSGLP RLTTSIDLEP KMSVALDGEV QAGPSQQQTD KDGTNPTGDR 

       910        920        930        940        950        960 
SAPRRARTAL PGVDGHTRCT RRSDRGPGER DANVRDKRPR RSMPPSRSVS SVPPPSSSGG 

       970        980 
GADGDRVEGA ARPRRQRRTP V 

« Hide

References

[1]"The sequence of RNA1 from Atlantic halibut nervous necrosis virus (AHNNV)."
Sommerset I., Nerland A.H.
Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
Strain: AH99NorA.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ401165 Genomic RNA. Translation: CAC17792.1.

3D structure databases

ProteinModelPortalQ9DIC5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view]
PfamPF00978. RdRP_2. 1 hit.
[Graphical view]
PROSITEPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRDRP_AHNNV
AccessionPrimary (citable) accession number: Q9DIC5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families