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Q9DIC5

- RDRP_AHNNV

UniProt

Q9DIC5 - RDRP_AHNNV

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Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Atlantic halibut nervous necrosis virus (AhNNV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Reviewed prediction.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. RNA binding Source: InterPro
  3. RNA-directed RNA polymerase activity Source: UniProtKB-KW

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
  2. viral RNA genome replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Short name:
RdRp
Alternative name(s):
RNA replicase
Short name:
Protein A
OrganismiAtlantic halibut nervous necrosis virus (AhNNV)
Taxonomic identifieri99486 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeBetanodavirus
Virus hostiHippoglossus hippoglossus (Atlantic halibut) (Pleuronectes hippoglossus) [TaxID: 8267]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 981981RNA-directed RNA polymerasePRO_0000222443Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9DIC5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini579 – 701123RdRp catalyticAdd
BLAST

Sequence similaritiesi

Family and domain databases

InterProiIPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view]
PfamiPF00978. RdRP_2. 1 hit.
[Graphical view]
PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DIC5-1 [UniParc]FASTAAdd to Basket

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MRSYEFHLAR MSGATLCVVT GYRLLTSKWL ADRIEDYRQR VIADRKKIIR    50
DAAMIRTSVQ KQMELVRISV RKGHSHQEAA TERNSATETM LSVVEKSGYE 100
PYIISPSPRE AEYHGSRQFY SLADFRQDYR RDEITDRHII VMTDVDYYVD 150
MNELIGLGVP VLMYTFQPST VSGEVKDGYF TITDDSVHYR VAGGKDVRHR 200
IWNYNQDTMY TVSRPTGFWE NLKRILRDIT GITALCGFLY NKLGMAPFGD 250
PVTMFTVDQF KMGEHRNIVS IVPFATCRSN LLKISEYGAE LEYMRYQQRN 300
NIANFNAVTY ISEEGPLISL GLEGNFASVQ LPLQDFENVR TAYELSKTNN 350
LSDTVRRSGR PCKEAAIIHK CLQAECVLAS EVVHKPGDLA RHYQAVGSLY 400
DVDPAEQGKC YAREYAPGPL TQTAVFPNES RSNERATIDG RIAGPQAKAK 450
SREHITPRMR KVARDFVRHL VPEAGLGRPY PLTYVEEQQS KPLQRARNDA 500
NRYHDEFTMI VKAFQKKEAY NAPNYPRNIS TVPHNQNVKL SSYTYAFKAS 550
TLQHVPWYMP THTPAEIADA VQNLAASTTE LVETDYSKFD GTFLRFMREC 600
VEFAIYKRWV HLDHLAELSQ LLANELQAPA VTRLGLKYDP DCSRLSGSAL 650
TTDGNSIANA FVSYLANRLA GMDDDEAWSW IGIVYGDDGL RSGNVSDTLL 700
TDTASSLGFD LKIVNRAPRG SPVTFLARVY LDPWSSPASV QSPFRTLLKL 750
HTTCDTQSEI EDIGWAKTQA YLVTDCKTPF IGHWCRAYQR NCTARVVQYA 800
DYNDIPFWVK NDDHLGNSWP QSDSVDWNDV VANELGLTTA ELLKHIALLE 850
AYTGPTSGLP RLTTSIDLEP KMSVALDGEV QAGPSQQQTD KDGTNPTGDR 900
SAPRRARTAL PGVDGHTRCT RRSDRGPGER DANVRDKRPR RSMPPSRSVS 950
SVPPPSSSGG GADGDRVEGA ARPRRQRRTP V 981
Length:981
Mass (Da):110,328
Last modified:March 1, 2001 - v1
Checksum:i6587D72D676FEA50
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ401165 Genomic RNA. Translation: CAC17792.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ401165 Genomic RNA. Translation: CAC17792.1 .

3D structure databases

ProteinModelPortali Q9DIC5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view ]
Pfami PF00978. RdRP_2. 1 hit.
[Graphical view ]
PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The sequence of RNA1 from Atlantic halibut nervous necrosis virus (AHNNV)."
    Sommerset I., Nerland A.H.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: AH99NorA.

Entry informationi

Entry nameiRDRP_AHNNV
AccessioniPrimary (citable) accession number: Q9DIC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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