Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9DIC5

- RDRP_AHNNV

UniProt

Q9DIC5 - RDRP_AHNNV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Atlantic halibut nervous necrosis virus (AhNNV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2.Curated

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. RNA binding Source: InterPro
  3. RNA-directed RNA polymerase activity Source: UniProtKB-KW

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
  2. viral RNA genome replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Short name:
RdRp
Alternative name(s):
RNA replicase
Short name:
Protein A
OrganismiAtlantic halibut nervous necrosis virus (AhNNV)
Taxonomic identifieri99486 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeBetanodavirus
Virus hostiHippoglossus hippoglossus (Atlantic halibut) (Pleuronectes hippoglossus) [TaxID: 8267]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 981981RNA-directed RNA polymerasePRO_0000222443Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9DIC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini579 – 701123RdRp catalyticPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nodaviridae RNA polymerase family.Curated
Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

Family and domain databases

InterProiIPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view]
PfamiPF00978. RdRP_2. 1 hit.
[Graphical view]
PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DIC5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRSYEFHLAR MSGATLCVVT GYRLLTSKWL ADRIEDYRQR VIADRKKIIR
60 70 80 90 100
DAAMIRTSVQ KQMELVRISV RKGHSHQEAA TERNSATETM LSVVEKSGYE
110 120 130 140 150
PYIISPSPRE AEYHGSRQFY SLADFRQDYR RDEITDRHII VMTDVDYYVD
160 170 180 190 200
MNELIGLGVP VLMYTFQPST VSGEVKDGYF TITDDSVHYR VAGGKDVRHR
210 220 230 240 250
IWNYNQDTMY TVSRPTGFWE NLKRILRDIT GITALCGFLY NKLGMAPFGD
260 270 280 290 300
PVTMFTVDQF KMGEHRNIVS IVPFATCRSN LLKISEYGAE LEYMRYQQRN
310 320 330 340 350
NIANFNAVTY ISEEGPLISL GLEGNFASVQ LPLQDFENVR TAYELSKTNN
360 370 380 390 400
LSDTVRRSGR PCKEAAIIHK CLQAECVLAS EVVHKPGDLA RHYQAVGSLY
410 420 430 440 450
DVDPAEQGKC YAREYAPGPL TQTAVFPNES RSNERATIDG RIAGPQAKAK
460 470 480 490 500
SREHITPRMR KVARDFVRHL VPEAGLGRPY PLTYVEEQQS KPLQRARNDA
510 520 530 540 550
NRYHDEFTMI VKAFQKKEAY NAPNYPRNIS TVPHNQNVKL SSYTYAFKAS
560 570 580 590 600
TLQHVPWYMP THTPAEIADA VQNLAASTTE LVETDYSKFD GTFLRFMREC
610 620 630 640 650
VEFAIYKRWV HLDHLAELSQ LLANELQAPA VTRLGLKYDP DCSRLSGSAL
660 670 680 690 700
TTDGNSIANA FVSYLANRLA GMDDDEAWSW IGIVYGDDGL RSGNVSDTLL
710 720 730 740 750
TDTASSLGFD LKIVNRAPRG SPVTFLARVY LDPWSSPASV QSPFRTLLKL
760 770 780 790 800
HTTCDTQSEI EDIGWAKTQA YLVTDCKTPF IGHWCRAYQR NCTARVVQYA
810 820 830 840 850
DYNDIPFWVK NDDHLGNSWP QSDSVDWNDV VANELGLTTA ELLKHIALLE
860 870 880 890 900
AYTGPTSGLP RLTTSIDLEP KMSVALDGEV QAGPSQQQTD KDGTNPTGDR
910 920 930 940 950
SAPRRARTAL PGVDGHTRCT RRSDRGPGER DANVRDKRPR RSMPPSRSVS
960 970 980
SVPPPSSSGG GADGDRVEGA ARPRRQRRTP V
Length:981
Mass (Da):110,328
Last modified:March 1, 2001 - v1
Checksum:i6587D72D676FEA50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ401165 Genomic RNA. Translation: CAC17792.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ401165 Genomic RNA. Translation: CAC17792.1 .

3D structure databases

ProteinModelPortali Q9DIC5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view ]
Pfami PF00978. RdRP_2. 1 hit.
[Graphical view ]
PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The sequence of RNA1 from Atlantic halibut nervous necrosis virus (AHNNV)."
    Sommerset I., Nerland A.H.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: AH99NorA.

Entry informationi

Entry nameiRDRP_AHNNV
AccessioniPrimary (citable) accession number: Q9DIC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2001
Last modified: October 1, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3