Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9DHT0 (PAP1_YLDV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:32L
OrganismYaba-like disease virus (YLDV)
Taxonomic identifier132475 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeYatapoxvirus
Virus hostHomo sapiens (Human) [TaxID: 9606]
Simiiformes [TaxID: 314293]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Keywords
   Biological processmRNA processing
Transcription
   LigandATP-binding
Nucleotide-binding
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

polynucleotide adenylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308943

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9DHT0 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 4B589FB8D6760FE4

FASTA47054,272
        10         20         30         40         50         60 
MSNSITLTLK NYLGRMPTIN EYHMLKSQVR NIQKIMFFNK DIFISLIKKN KKKFFSEIKS 

        70         80         90        100        110        120 
SPSEIKTHIL EYFLKQQKTS SIGKLYTIIE LQTILVSSYT DVLGVLTTKS PYVFPSNIKY 

       130        140        150        160        170        180 
EPHSMKKIAH DILTSINVAT ISEKVMGRHN VSNLVTNVNL LMEEYLRRHN KSCICYGSYS 

       190        200        210        220        230        240 
LYLLNPSIKY GDIDILQTNS RIFLINLAFL IKFITGHNVM LLKVPYLKNY MVLRDNEDKH 

       250        260        270        280        290        300 
IIDSFNVRQE TMHAIPKILI DNIYIVDPTF QLLSMIKMFS QIDRLEDLAK NQEKATIKLA 

       310        320        330        340        350        360 
TLLEYVRIKH GIILNGNVTN MPMPASFNYE KRIVTVDASK YNFSFKKCFV YLDENSLSSD 

       370        380        390        400        410        420 
ILDLNADDAI DFENVSNSVF LINDEVMYTY FSNTILMSSK NEIHEISARG VSAHILMYQI 

       430        440        450        460        470 
LTDGDFLIPL SDIINSLMFK EKTPIFNIIP RDKKTGKHGI INIEKDIITH 

« Hide

References

[1]"The genome sequence of Yaba-like disease virus, a yatapoxvirus."
Lee H.-J., Essani K., Smith G.L.
Virology 281:170-192(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ293568 Genomic DNA. Translation: CAC21270.1.
RefSeqNP_073417.1. NC_002642.1.

3D structure databases

ProteinModelPortalQ9DHT0.
SMRQ9DHT0. Positions 9-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID918743.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_YLDV
AccessionPrimary (citable) accession number: Q9DHT0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families