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Protein

Translationally-controlled tumor protein homolog

Gene

tpt1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Gene namesi
Name:tpt1
Synonyms:tct1, tctp
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-990603-10 tpt1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002112741 – 171Translationally-controlled tumor protein homologAdd BLAST171

Proteomic databases

PaxDbiQ9DGK4
PRIDEiQ9DGK4

Expressioni

Gene expression databases

BgeeiENSDARG00000092693
ExpressionAtlasiQ9DGK4 baseline

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000110449

Structurei

3D structure databases

ProteinModelPortaliQ9DGK4
SMRiQ9DGK4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 171TCTPPROSITE-ProRule annotationAdd BLAST171

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727 Eukaryota
ENOG4111FVP LUCA
GeneTreeiENSGT00390000006051
HOGENOMiHOG000203361
HOVERGENiHBG002282
InParanoidiQ9DGK4
OMAiFKDFEFY
PhylomeDBiQ9DGK4
TreeFamiTF300238

Family and domain databases

Gene3Di2.170.150.10, 1 hit
InterProiView protein in InterPro
IPR011057 Mss4-like_sf
IPR011323 Mss4/transl-control_tumor
IPR034737 TCTP
IPR018103 Translation_control_tumour_CS
IPR018105 Translational_control_tumour_p
PANTHERiPTHR11991 PTHR11991, 1 hit
PfamiView protein in Pfam
PF00838 TCTP, 1 hit
PRINTSiPR01653 TCTPROTEIN
SUPFAMiSSF51316 SSF51316, 1 hit
PROSITEiView protein in PROSITE
PS01002 TCTP_1, 1 hit
PS01003 TCTP_2, 1 hit
PS51797 TCTP_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9DGK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYKDIITG DEMFSDIYKI KESENGMMLE VEGKMITRAE GDIDDALIGG
60 70 80 90 100
NASAEVADEG CDSTSVSGVD IVLNHKLQET SYDKKSYTAY IKDYMKAVKA
110 120 130 140 150
KLQESAPNRV DPFMANAPAE VKKILGNIKN FQFFTGESMN PDGMIGLLDF
160 170
REDGVTPYMI FFKDGLEIEK C
Length:171
Mass (Da):19,025
Last modified:March 1, 2001 - v1
Checksum:i2D56CDCDAA74DE5C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti161F → S in AAH49059 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF288217 mRNA Translation: AAF99708.1
BC049059 mRNA Translation: AAH49059.1
RefSeqiNP_937783.1, NM_198140.1
UniGeneiDr.75674

Genome annotation databases

EnsembliENSDART00000102111; ENSDARP00000092887; ENSDARG00000092693
GeneIDi30723
KEGGidre:30723

Similar proteinsi

Entry informationi

Entry nameiTCTP_DANRE
AccessioniPrimary (citable) accession number: Q9DGK4
Secondary accession number(s): Q7ZUG2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health