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Protein
Submitted name:

Enhancer of split groucho

Gene

tle1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Enhancer of split grouchoImported
Gene namesi
Name:tle1Imported
Synonyms:ESG1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6252455. tle1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ9DGK0.
SMRiQ9DGK0. Positions 424-756.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini466 – 639174WD_REPEATS_REGIONInterPro annotationAdd
BLAST
Domaini680 – 75677WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili35 – 6228Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatUniRule annotation

Phylogenomic databases

HOVERGENiHBG004689.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR005617. Groucho/TLE_N.
IPR009146. Groucho_enhance.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF03920. TLE_N. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
PRINTSiPR01850. GROUCHOFAMLY.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DGK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPQNRPPTH LQASVATGAA SGPPQSLKLT YPETLDRIKE EFQFLQSQYH
60 70 80 90 100
SLKLECEKLA TEKTEIQRHY VMYYEMSYGL NIEMHKQTEI AKRLNVICAQ
110 120 130 140 150
LVPFLSQEHQ QQVVQAVERA KQVTMAELNA AIGHQLQAQH LSHHAPPIPL
160 170 180 190 200
TPHPSSLQHP GLAAATSASS LLALSGVLGL QTQLAAKEGL ADAEHRERDP
210 220 230 240 250
GPSCLTLPNG ERVRTLSDYL NSNKKRKTEE KDFGTDYGSD ADRSEDNLVV
260 270 280 290 300
DEDPASPHSV HSYSSRENGV DKSLQRKEPP PASPNSMTSS SSVSPSRSKD
310 320 330 340 350
IPSQVEKAGT PGLKSSTPNS QSDLNTPGPS GSSASQFRSI TTKPAIDSLA
360 370 380 390 400
LGLRTPLGGQ GGYPAAFSIA HPSVNADGAG AYAGLHLMSP QIDGATAAGT
410 420 430 440 450
YGRSPLVSYD PHAHMRGLGS AIPGSASGKP AYSFHVSADG QMQPVPFPPD
460 470 480 490 500
ALIGSGIPRH ARQLHVLNHG EVVCAVTISN STRHVYTGGK GCVKVWDVGQ
510 520 530 540 550
PGTKTPVAQL DCLNRDNYIR SCKLLPDGRS LIVGGEASTL SIWDLASPTP
560 570 580 590 600
RIKAELTSSA PACYALAISP DAKVCFSCCS DGNIVVWDLQ NQTLVRQFQG
610 620 630 640 650
HTDGASCIDI SHDGTKLWTG GLDNTVRCWD LREGRQLQQH DFNSQIFSLG
660 670 680 690 700
YCPTGEWLAV GMESSNIEVL HVSKPDKYQL HLHESCVLSL QFASCGKWFV
710 720 730 740 750
STGKDNLLNA WRTPYGASIF QSKESSSVLS CDVSTDDQFI VTGSGDKKAT

VYEVIY
Length:756
Mass (Da):81,423
Last modified:March 1, 2001 - v1
Checksum:i5EEB37FC55FE1E69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF289027 mRNA. Translation: AAG01027.1.
RefSeqiNP_001090448.1. NM_001096979.1.
UniGeneiXl.57178.

Genome annotation databases

GeneIDi779361.
KEGGixla:779361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF289027 mRNA. Translation: AAG01027.1.
RefSeqiNP_001090448.1. NM_001096979.1.
UniGeneiXl.57178.

3D structure databases

ProteinModelPortaliQ9DGK0.
SMRiQ9DGK0. Positions 424-756.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi779361.
KEGGixla:779361.

Organism-specific databases

CTDi7088.
XenbaseiXB-GENE-6252455. tle1.

Phylogenomic databases

HOVERGENiHBG004689.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR005617. Groucho/TLE_N.
IPR009146. Groucho_enhance.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF03920. TLE_N. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
PRINTSiPR01850. GROUCHOFAMLY.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4."
    Pukrop T., Gradl D., Henningfeld K.A., Knoechel W., Wedlich D., Kuehl M.
    J. Biol. Chem. 276:8968-8978(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9DGK0_XENLA
AccessioniPrimary (citable) accession number: Q9DGK0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: June 8, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.