Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Vanilloid receptor-related osmotically activated channel protein

Gene

VR-OAC

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Vanilloid receptor-related osmotically activated channel proteinImported
Gene namesi
Name:VR-OACImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9DFS3.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022441.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3JXIX-ray2.30A/B/C/D133-382[»]
3JXJX-ray2.80A/B133-382[»]
3W9FX-ray1.90A/B/C/D133-382[»]
3W9GX-ray2.00A/B/C/D133-382[»]
ProteinModelPortaliQ9DFS3.
SMRiQ9DFS3. Positions 135-380.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9DFS3.

Family & Domainsi

Sequence similaritiesi

Contains 3 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotationSAAS annotation, RepeatUniRule annotation, TransmembraneUniRule annotation

Phylogenomic databases

eggNOGiNOG278734.
HOGENOMiHOG000234630.
HOVERGENiHBG054085.
PhylomeDBiQ9DFS3.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR008347. TRPV1-4_channel.
IPR008348. TRPV4_channel.
[Graphical view]
PANTHERiPTHR10582:SF4. PTHR10582:SF4. 1 hit.
PfamiPF00023. Ank. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01768. TRPVRECEPTOR.
PR01769. VRL2RECEPTOR.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 2 hits.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DFS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPEDPRDA GDVLGDDSFP LSSLANLFEV EDTPSPAEPS RGPPGAGDGK
60 70 80 90 100
QNLRMKFHGA FRKGPPKPME LLESTIYESS VVPAPKKAPM DSLFDYGTYR
110 120 130 140 150
QHPSENKRWR RRVVEKPVAG TKGPAPNPPP VLKVFNRPIL FDIVSRGSPD
160 170 180 190 200
GLEGLLSFLL THKKRLTDEE FREPSTGKTC LPKALLNLSA GRNDTIPILL
210 220 230 240 250
DIAEKTGNMR EFINSPFRDV YYRGQTALHI AIERRCKHYV ELLVEKGADV
260 270 280 290 300
HAQARGRFFQ PKDEGGYFYF GELPLSLAAC TNQPHIVHYL TENGHKQADL
310 320 330 340 350
RRQDSRGNTV LHALVAIADN TRENTKFVTK MYDLLLIKCA KLFPDTNLEA
360 370 380 390 400
LLNNDGLSPL MMAAKTGKIG IFQHIIRREI ADEDVRHLSR KFKDWAYGPV
410 420 430 440 450
YSSLYDLSSL DTCGEEVSVL EILVYNSKIE NRHEMLAVEP INELLRDKWR
460 470 480 490 500
KFGAVSFYIS VVSYLCAMII FTLIAYYRPM EGPPPYPYTT TIDYLRLAGE
510 520 530 540 550
IITLLTGILF FFSNIKDLFM KKCPGVNSFF IDGSFQLLYF IYSVLVIVTA
560 570 580 590 600
GLYLGGVEAY LAVMVFALVL GWMNALYFTR GLKLTGTYSI MIQKILFKDL
610 620 630 640 650
FRFLLVYLLF MIGYASALVS LLNPCPSSES CSEDHSNCTL PTYPSCRDSQ
660 670 680 690 700
TFSTFLLDLF KLTIGMGDLE MLESAKYPGV FIILLVTYII LTFVLLLNML
710 720 730 740 750
IALMGETVGQ VSKESKHIWK LQWATTILDI ERSFPLFLRR AFRSGEMVTV
760 770 780 790 800
GKGTDGTPDR RWCFRVDEVN WSHWNQNLGI ISEDPGKSDT YQYYGFSHTV
810 820 830 840 850
GRLRRDRWST VVPRVVELNK SCPTEDVVVP LGTMGTAEAR ERRHGQTPSS

PL
Length:852
Mass (Da):96,198
Last modified:March 1, 2001 - v1
Checksum:iE85365D3FADD08C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF261883 mRNA. Translation: AAG28026.1.
RefSeqiNP_990023.1. NM_204692.1.
UniGeneiGga.51246.

Genome annotation databases

GeneIDi395427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF261883 mRNA. Translation: AAG28026.1.
RefSeqiNP_990023.1. NM_204692.1.
UniGeneiGga.51246.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3JXIX-ray2.30A/B/C/D133-382[»]
3JXJX-ray2.80A/B133-382[»]
3W9FX-ray1.90A/B/C/D133-382[»]
3W9GX-ray2.00A/B/C/D133-382[»]
ProteinModelPortaliQ9DFS3.
SMRiQ9DFS3. Positions 135-380.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022441.

Proteomic databases

PaxDbiQ9DFS3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395427.

Organism-specific databases

CTDi59341.

Phylogenomic databases

eggNOGiNOG278734.
HOGENOMiHOG000234630.
HOVERGENiHBG054085.
PhylomeDBiQ9DFS3.

Miscellaneous databases

EvolutionaryTraceiQ9DFS3.
NextBioi20815511.
PROiQ9DFS3.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR008347. TRPV1-4_channel.
IPR008348. TRPV4_channel.
[Graphical view]
PANTHERiPTHR10582:SF4. PTHR10582:SF4. 1 hit.
PfamiPF00023. Ank. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01768. TRPVRECEPTOR.
PR01769. VRL2RECEPTOR.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 2 hits.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor."
    Liedtke W.B., Choe Y., Marti-Renom M.A., Bell A.M., Denis C.S., Sali A., Hudspeth A.J., Friedman J.M., Heller S.
    Cell 103:525-535(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CochleaImported.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 133-382.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 133-382.

Entry informationi

Entry nameiQ9DFS3_CHICK
AccessioniPrimary (citable) accession number: Q9DFS3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 27, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.