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Protein
Submitted name:

Vanilloid receptor-related osmotically activated channel protein

Gene

VR-OAC

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelSAAS annotation, ReceptorImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Vanilloid receptor-related osmotically activated channel proteinImported
Gene namesi
Name:VR-OACImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei455 – 477HelicalSequence analysisAdd BLAST23
Transmembranei497 – 515HelicalSequence analysisAdd BLAST19
Transmembranei536 – 554HelicalSequence analysisAdd BLAST19
Transmembranei560 – 579HelicalSequence analysisAdd BLAST20
Transmembranei600 – 622HelicalSequence analysisAdd BLAST23
Transmembranei680 – 703HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9DFS3.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JXIX-ray2.30A/B/C/D133-382[»]
3JXJX-ray2.80A/B133-382[»]
3W9FX-ray1.90A/B/C/D133-382[»]
3W9GX-ray2.00A/B/C/D133-382[»]
ProteinModelPortaliQ9DFS3.
SMRiQ9DFS3.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9DFS3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini223 – 378ANK_REP_REGIONInterPro annotationAdd BLAST156
Repeati223 – 255ANKPROSITE-ProRule annotationAdd BLAST33

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3676. Eukaryota.
ENOG4110DG4. LUCA.
HOGENOMiHOG000234630.
HOVERGENiHBG054085.
PhylomeDBiQ9DFS3.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR024862. TRPV.
IPR008347. TRPV1-4_channel.
IPR008348. TRPV4_channel.
PANTHERiPTHR10582. PTHR10582. 1 hit.
PTHR10582:SF4. PTHR10582:SF4. 1 hit.
PfamiView protein in Pfam
PF00023. Ank. 1 hit.
PF00520. Ion_trans. 1 hit.
PRINTSiPR01768. TRPVRECEPTOR.
PR01769. VRL2RECEPTOR.
SMARTiView protein in SMART
SM00248. ANK. 3 hits.
SUPFAMiSSF48403. SSF48403. 2 hits.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9DFS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPEDPRDA GDVLGDDSFP LSSLANLFEV EDTPSPAEPS RGPPGAGDGK
60 70 80 90 100
QNLRMKFHGA FRKGPPKPME LLESTIYESS VVPAPKKAPM DSLFDYGTYR
110 120 130 140 150
QHPSENKRWR RRVVEKPVAG TKGPAPNPPP VLKVFNRPIL FDIVSRGSPD
160 170 180 190 200
GLEGLLSFLL THKKRLTDEE FREPSTGKTC LPKALLNLSA GRNDTIPILL
210 220 230 240 250
DIAEKTGNMR EFINSPFRDV YYRGQTALHI AIERRCKHYV ELLVEKGADV
260 270 280 290 300
HAQARGRFFQ PKDEGGYFYF GELPLSLAAC TNQPHIVHYL TENGHKQADL
310 320 330 340 350
RRQDSRGNTV LHALVAIADN TRENTKFVTK MYDLLLIKCA KLFPDTNLEA
360 370 380 390 400
LLNNDGLSPL MMAAKTGKIG IFQHIIRREI ADEDVRHLSR KFKDWAYGPV
410 420 430 440 450
YSSLYDLSSL DTCGEEVSVL EILVYNSKIE NRHEMLAVEP INELLRDKWR
460 470 480 490 500
KFGAVSFYIS VVSYLCAMII FTLIAYYRPM EGPPPYPYTT TIDYLRLAGE
510 520 530 540 550
IITLLTGILF FFSNIKDLFM KKCPGVNSFF IDGSFQLLYF IYSVLVIVTA
560 570 580 590 600
GLYLGGVEAY LAVMVFALVL GWMNALYFTR GLKLTGTYSI MIQKILFKDL
610 620 630 640 650
FRFLLVYLLF MIGYASALVS LLNPCPSSES CSEDHSNCTL PTYPSCRDSQ
660 670 680 690 700
TFSTFLLDLF KLTIGMGDLE MLESAKYPGV FIILLVTYII LTFVLLLNML
710 720 730 740 750
IALMGETVGQ VSKESKHIWK LQWATTILDI ERSFPLFLRR AFRSGEMVTV
760 770 780 790 800
GKGTDGTPDR RWCFRVDEVN WSHWNQNLGI ISEDPGKSDT YQYYGFSHTV
810 820 830 840 850
GRLRRDRWST VVPRVVELNK SCPTEDVVVP LGTMGTAEAR ERRHGQTPSS

PL
Length:852
Mass (Da):96,198
Last modified:March 1, 2001 - v1
Checksum:iE85365D3FADD08C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF261883 mRNA. Translation: AAG28026.1.
RefSeqiNP_990023.1. NM_204692.1.
UniGeneiGga.51246.

Genome annotation databases

GeneIDi395427.

Similar proteinsi

Entry informationi

Entry nameiQ9DFS3_CHICK
AccessioniPrimary (citable) accession number: Q9DFS3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 25, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources