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Q9DFS3 (Q9DFS3_CHICK) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:VR-OAC EMBL AAG28026.1
OrganismGallus gallus (Chicken) EMBL AAG28026.1
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length852 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 3 ANK repeats. RuleBase RU003321

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site2561Phosphate; via amide nitrogen PDB 3JXJ
Binding site2671Phosphate PDB 3JXJ
Binding site2721Phosphate PDB 3JXJ

Sequences

Sequence LengthMass (Da)Tools
Q9DFS3 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: E85365D3FADD08C1

FASTA85296,198
        10         20         30         40         50         60 
MADPEDPRDA GDVLGDDSFP LSSLANLFEV EDTPSPAEPS RGPPGAGDGK QNLRMKFHGA 

        70         80         90        100        110        120 
FRKGPPKPME LLESTIYESS VVPAPKKAPM DSLFDYGTYR QHPSENKRWR RRVVEKPVAG 

       130        140        150        160        170        180 
TKGPAPNPPP VLKVFNRPIL FDIVSRGSPD GLEGLLSFLL THKKRLTDEE FREPSTGKTC 

       190        200        210        220        230        240 
LPKALLNLSA GRNDTIPILL DIAEKTGNMR EFINSPFRDV YYRGQTALHI AIERRCKHYV 

       250        260        270        280        290        300 
ELLVEKGADV HAQARGRFFQ PKDEGGYFYF GELPLSLAAC TNQPHIVHYL TENGHKQADL 

       310        320        330        340        350        360 
RRQDSRGNTV LHALVAIADN TRENTKFVTK MYDLLLIKCA KLFPDTNLEA LLNNDGLSPL 

       370        380        390        400        410        420 
MMAAKTGKIG IFQHIIRREI ADEDVRHLSR KFKDWAYGPV YSSLYDLSSL DTCGEEVSVL 

       430        440        450        460        470        480 
EILVYNSKIE NRHEMLAVEP INELLRDKWR KFGAVSFYIS VVSYLCAMII FTLIAYYRPM 

       490        500        510        520        530        540 
EGPPPYPYTT TIDYLRLAGE IITLLTGILF FFSNIKDLFM KKCPGVNSFF IDGSFQLLYF 

       550        560        570        580        590        600 
IYSVLVIVTA GLYLGGVEAY LAVMVFALVL GWMNALYFTR GLKLTGTYSI MIQKILFKDL 

       610        620        630        640        650        660 
FRFLLVYLLF MIGYASALVS LLNPCPSSES CSEDHSNCTL PTYPSCRDSQ TFSTFLLDLF 

       670        680        690        700        710        720 
KLTIGMGDLE MLESAKYPGV FIILLVTYII LTFVLLLNML IALMGETVGQ VSKESKHIWK 

       730        740        750        760        770        780 
LQWATTILDI ERSFPLFLRR AFRSGEMVTV GKGTDGTPDR RWCFRVDEVN WSHWNQNLGI 

       790        800        810        820        830        840 
ISEDPGKSDT YQYYGFSHTV GRLRRDRWST VVPRVVELNK SCPTEDVVVP LGTMGTAEAR 

       850 
ERRHGQTPSS PL 

« Hide

References

[1]"Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor."
Liedtke W.B., Choe Y., Marti-Renom M.A., Bell A.M., Denis C.S., Sali A., Hudspeth A.J., Friedman J.M., Heller S.
Cell 103:525-535(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Cochlea EMBL AAG28026.1.
[2]"Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C."
Landoure G., Zdebik A.A., Martinez T.L., Burnett B.G., Stanescu H.C., Inada H., Shi Y., Taye A.A., Kong L., Munns C.H., Choo S.S., Phelps C.B., Paudel R., Houlden H., Ludlow C.L., Caterina M.J., Gaudet R., Kleta R., Fischbeck K.H., Sumner C.J.
Nat. Genet. 42:170-174(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 133-382 IN COMPLEX WITH PHOSPHATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF261883 mRNA. Translation: AAG28026.1.
RefSeqNP_990023.1. NM_204692.1.
UniGeneGga.51246.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3JXIX-ray2.30A/B/C/D133-382[»]
3JXJX-ray2.80A/B133-382[»]
ProteinModelPortalQ9DFS3.
SMRQ9DFS3. Positions 135-380.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000022441.

Proteomic databases

PaxDbQ9DFS3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID395427.
KEGGgga:395427.

Organism-specific databases

CTD59341.

Phylogenomic databases

eggNOGNOG278734.
HOGENOMHOG000234630.
HOVERGENHBG054085.
InParanoidQ9DFS3.
KOK04973.
PhylomeDBQ9DFS3.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR024862. TRPV.
IPR008347. TRPV1-4_channel.
IPR008348. TRPV4_channel.
[Graphical view]
PANTHERPTHR10582. PTHR10582. 1 hit.
PTHR10582:SF4. PTHR10582:SF4. 1 hit.
PfamPF00023. Ank. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR01768. TRPVRECEPTOR.
PR01769. VRL2RECEPTOR.
SMARTSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 2 hits.
TIGRFAMsTIGR00870. trp. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9DFS3.
NextBio20815511.
PROQ9DFS3.

Entry information

Entry nameQ9DFS3_CHICK
AccessionPrimary (citable) accession number: Q9DFS3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)