Q9DF41 (Q9DF41_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
BHLH-WRPW transcription factor EMBL AAG23838.1

Submitted name:
Hairy-related 9 EMBL AAH79516.1
Submitted name:
Uncharacterized protein Ensembl ENSDARP00000073394

Gene names

Name:

her9 ZFIN ZDB-GENE-011213-1 EMBL AAG23838.1 Ensembl ENSDARP00000073394

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 Orange domain. SAAS SAAS003650 Contains 1 bHLH (basic helix-loop-helix) domain. SAAS SAAS003650 Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS003650
Cellular component	Nucleus SAAS SAAS003650
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	negative regulation of neurogenesis Inferred from mutant phenotype PubMed 15716337. Source: ZFIN regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9DF41 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 817B630F296994A2	FASTA	291	31,002
	10 20 30 40 50 60 MPADNMEKQT ASPIAGAPAS GSHTPDKPKN ASEHRKSSKP IMEKRRRARI NESLGQLKTL 70 80 90 100 110 120 ILDALKKDSS RHSKLEKADI LEMTVKHLRN LQRVQMSAAL SADTNVLSKY RAGFNECMNE 130 140 150 160 170 180 VTRFLSTCEG VNTEVRSRLL NHLSGCMGQM MAMNYPQPAP AQQAHLAQPL HVQLPSTLPI 190 200 210 220 230 240 NGASMGSKLS PSEAVSPKVF GGFQLVPATD GQFAFLIPNP AFASATTPVI PLYANASVPV 250 260 270 280 290 TVNASPVQAS SAPTVASPVQ GMTSFSGVPQ AVSPVGVSAG AESNEPVWRP W

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Homologues of c-hairy1 (her9) and lunatic fringe in zebrafish are expressed in the developing central nervous system, but not in the presomitic mesoderm." Leve C., Gajewski M., Rohr K.B., Tautz D. Dev. Genes Evol. 211:493-500(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Singapore local strain EMBL AAH79516.1. Tissue: Embryo EMBL AAH79516.1.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000073394.
[4]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000073394.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR751236 Genomic DNA. No translation available. AF301264 mRNA. Translation: AAG23838.1. BC079516 mRNA. Translation: AAH79516.1.
IPI	IPI00506831.
RefSeq	NP_571948.1. NM_131873.1.
UniGene	Dr.78757.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000078936; ENSDARP00000073394; ENSDARG00000056438.
GeneID	140613.
KEGG	dre:140613.
Organism-specific databases
CTD	140613.
ZFIN	ZDB-GENE-011213-1. her9.
Phylogenomic databases
GeneTree	ENSGT00700000104168.
HOVERGEN	HBG005960.
InParanoid	Q9DF41.
KO	K06054.
OMA	HTPDKPK.
Family and domain databases
Gene3D	4.10.280.10. 1 hit.
InterPro	IPR011598. bHLH_dom. IPR003650. Orange. IPR018352. Orange_subgr. [Graphical view]
Pfam	PF07527. Hairy_orange. 1 hit. PF00010. HLH. 1 hit. [Graphical view]
SMART	SM00353. HLH. 1 hit. SM00511. ORANGE. 1 hit. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
PROSITE	PS50888. BHLH. 1 hit. PS51054. ORANGE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20797024.

Entry information

Entry name

Q9DF41_DANRE

Accession

Primary (citable) accession number: Q9DF41

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)