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Protein
Submitted name:

Transcription factor Her-8a

Gene

her8a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • gliogenesis Source: ZFIN
  • negative regulation of neurogenesis Source: ZFIN
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor Her-8aImported
Gene namesi
Name:her8aImported
Synonyms:her-8aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-030131-2376. her8a.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ9DEU8.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000111735.

Structurei

3D structure databases

ProteinModelPortaliQ9DEU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 7355BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST
Domaini95 – 12834OrangeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation
Contains Orange domain.SAAS annotation
Contains bHLH (basic helix-loop-helix) domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG4304. Eukaryota.
ENOG4111F0X. LUCA.
HOVERGENiHBG107098.
PhylomeDBiQ9DEU8.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003650. Orange_dom.
[Graphical view]
PfamiPF07527. Hairy_orange. 1 hit.
PF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00511. ORANGE. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
PS51054. ORANGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DEU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTASNMGNGP EKNFNAKEER KLRKPLIEKK RRERINSSLE QLKGIMVDAY
60 70 80 90 100
NLDQSKLEKA DVLEITVQHM ENLQRGHGQG GSNSPGTGFE SRQRYSSGYI
110 120 130 140 150
QCMHEVHNLL LSCPGMDKTL GARLLNHLLK SLPHISTEPS GTSSAGTSSP
160 170 180 190 200
LPLSPTQSPI NLPSSLQPHA LHLSPSPPSS PTHSLVRPRE QFSPPSSPSP
210 220
QSPASLPPFF PGVDPSMWRP W
Length:221
Mass (Da):24,223
Last modified:March 1, 2001 - v1
Checksum:iAD5FB72CBDDED94C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007990 mRNA. Translation: AAG23291.1.
UniGeneiDr.74550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007990 mRNA. Translation: AAG23291.1.
UniGeneiDr.74550.

3D structure databases

ProteinModelPortaliQ9DEU8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000111735.

Proteomic databases

PaxDbiQ9DEU8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-030131-2376. her8a.

Phylogenomic databases

eggNOGiKOG4304. Eukaryota.
ENOG4111F0X. LUCA.
HOVERGENiHBG107098.
PhylomeDBiQ9DEU8.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003650. Orange_dom.
[Graphical view]
PfamiPF07527. Hairy_orange. 1 hit.
PF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00511. ORANGE. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
PS51054. ORANGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9DEU8_DANRE
AccessioniPrimary (citable) accession number: Q9DEU8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.