Q9DER6 (Q9DER6_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Coagulation factor XIIIA EMBL CAC10657.1
Organism	Gallus gallus (Chicken) EMBL CAC10657.1
Taxonomic identifier	9031 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	736 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor

Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Gene Ontology (GO)
Biological_process	peptide cross-linking Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	322	1	By similarity PIRSR PIRSR000459-1
	Active site	381	1	By similarity PIRSR PIRSR000459-1
	Active site	404	1	By similarity PIRSR PIRSR000459-1
	Metal binding	444	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	446	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	493	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	498	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	Q9DER6 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 100F69C0268C0331	FASTA	736	83,749
	10 20 30 40 50 60 MSEPTSTDRE KKRPPLNGRR ALPSNNSNAE ENDVPEMDAF GLIPRGFNPK DYLRVVDIHM 70 80 90 100 110 120 FKEPNEINKQ QHHTDKYYNP KLIVRRGQPF QIQIDFSRPY DPEKDQIWLE YLIGRYPQPN 130 140 150 160 170 180 KGTYIPILIG DVLKPGEWGA KITHRENNSI RLSIMSSATC IIGKFRLYIA IWTPYGIIRT 190 200 210 220 230 240 HRNSATDTYI LFNPWCQLDA VYLDDEKERE EYVLNDVGIV FHGDVNEVKL RSWSYGQFEE 250 260 270 280 290 300 NILDACLFLM DKAELELSGR GNPIKICRVA SAMINSKDDN GVLAGSWDNL YDYGVPPSAW 310 320 330 340 350 360 TGSVDILLEY YSSKQPVRYG QCWVFAGVFN TFLRCLGIPA RLITNYSSAH DNNANLQLDF 370 380 390 400 410 420 FLDDEGQVDN RLTKDSVWNY HCWNEAWMTR PDLPVGFGGW QAVDGTPQET SDGMYRCGPA 430 440 450 460 470 480 SVQAIKHGHV CFQFDAPFVY AEVNSDIIYS RMGKNGSQVI EKIDTTHIGK LIVTKGVGND 490 500 510 520 530 540 DMVDITENYK FQEGSAEERL ALETAVMYGV KKQTTQPTTY QPQKDIEMDL QVQKVVLGSD 550 560 570 580 590 600 FKVTIILRNK SRNSYTATTY LSGNIVFYTG VTKSEFKKHS FSAKLEPLLS NTFDVMITSA 610 620 630 640 650 660 EYLNDLLDQA SFHFFVTARI NETGKVLAMQ KAVVLEIPTL KIKTKGQMVV DRETSVVVEF 670 680 690 700 710 720 TNPLKQTLEN ATLRLEGPGV LRTMKKEFRQ IPAMSTLIWD VKCIPKRPGL RKLIASLNCD 730 ALRHVYGELN IQVQKP

References

[1]

"Chicken coagulation factor XIIIA is produced by the theca externa and stabilizes the ovarian follicular wall." Recheis B., Osanger A., Haubenwallner S., Schneider W.J., Nimpf J. J. Biol. Chem. 275:35320-35327(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: White Leghorn EMBL CAC10657.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ278103 mRNA. Translation: CAC10657.1.
IPI	IPI00588151.
RefSeq	NP_990016.1. NM_204685.1.
UniGene	Gga.226.
3D structure databases
HSSP	HSSP built from PDB template 1EVU based on UniProtKB P00488.
ProteinModelPortal	Q9DER6.
SMR	Q9DER6. Positions 18-734.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	395420.
KEGG	gga:395420.
Organism-specific databases
CTD	2162.
Phylogenomic databases
HOGENOM	HOG000231695.
HOVERGEN	HBG004342.
InParanoid	Q9DER6.
KO	K03917.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20815504.

Entry information

Entry name

Q9DER6_CHICK

Accession

Primary (citable) accession number: Q9DER6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)