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Protein
Submitted name:

Coagulation factor XIIIA

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei322 – 3221UniRule annotation
Active sitei381 – 3811UniRule annotation
Active sitei404 – 4041UniRule annotation
Metal bindingi444 – 4441CalciumUniRule annotation
Metal bindingi446 – 4461CalciumUniRule annotation
Metal bindingi493 – 4931CalciumUniRule annotation
Metal bindingi498 – 4981CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIIIAImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Structurei

3D structure databases

ProteinModelPortaliQ9DER6.
SMRiQ9DER6. Positions 18-734.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000231695.
HOVERGENiHBG004342.
KOiK03917.
PhylomeDBiQ9DER6.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DER6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPTSTDRE KKRPPLNGRR ALPSNNSNAE ENDVPEMDAF GLIPRGFNPK
60 70 80 90 100
DYLRVVDIHM FKEPNEINKQ QHHTDKYYNP KLIVRRGQPF QIQIDFSRPY
110 120 130 140 150
DPEKDQIWLE YLIGRYPQPN KGTYIPILIG DVLKPGEWGA KITHRENNSI
160 170 180 190 200
RLSIMSSATC IIGKFRLYIA IWTPYGIIRT HRNSATDTYI LFNPWCQLDA
210 220 230 240 250
VYLDDEKERE EYVLNDVGIV FHGDVNEVKL RSWSYGQFEE NILDACLFLM
260 270 280 290 300
DKAELELSGR GNPIKICRVA SAMINSKDDN GVLAGSWDNL YDYGVPPSAW
310 320 330 340 350
TGSVDILLEY YSSKQPVRYG QCWVFAGVFN TFLRCLGIPA RLITNYSSAH
360 370 380 390 400
DNNANLQLDF FLDDEGQVDN RLTKDSVWNY HCWNEAWMTR PDLPVGFGGW
410 420 430 440 450
QAVDGTPQET SDGMYRCGPA SVQAIKHGHV CFQFDAPFVY AEVNSDIIYS
460 470 480 490 500
RMGKNGSQVI EKIDTTHIGK LIVTKGVGND DMVDITENYK FQEGSAEERL
510 520 530 540 550
ALETAVMYGV KKQTTQPTTY QPQKDIEMDL QVQKVVLGSD FKVTIILRNK
560 570 580 590 600
SRNSYTATTY LSGNIVFYTG VTKSEFKKHS FSAKLEPLLS NTFDVMITSA
610 620 630 640 650
EYLNDLLDQA SFHFFVTARI NETGKVLAMQ KAVVLEIPTL KIKTKGQMVV
660 670 680 690 700
DRETSVVVEF TNPLKQTLEN ATLRLEGPGV LRTMKKEFRQ IPAMSTLIWD
710 720 730
VKCIPKRPGL RKLIASLNCD ALRHVYGELN IQVQKP
Length:736
Mass (Da):83,749
Last modified:March 1, 2001 - v1
Checksum:i100F69C0268C0331
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ278103 mRNA. Translation: CAC10657.1.
RefSeqiNP_990016.1. NM_204685.1.
UniGeneiGga.226.

Genome annotation databases

GeneIDi395420.
KEGGigga:395420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ278103 mRNA. Translation: CAC10657.1.
RefSeqiNP_990016.1. NM_204685.1.
UniGeneiGga.226.

3D structure databases

ProteinModelPortaliQ9DER6.
SMRiQ9DER6. Positions 18-734.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395420.
KEGGigga:395420.

Organism-specific databases

CTDi2162.

Phylogenomic databases

HOGENOMiHOG000231695.
HOVERGENiHBG004342.
KOiK03917.
PhylomeDBiQ9DER6.

Miscellaneous databases

NextBioi20815504.
PROiQ9DER6.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Chicken coagulation factor XIIIA is produced by the theca externa and stabilizes the ovarian follicular wall."
    Recheis B., Osanger A., Haubenwallner S., Schneider W.J., Nimpf J.
    J. Biol. Chem. 275:35320-35327(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White LeghornImported.

Entry informationi

Entry nameiQ9DER6_CHICK
AccessioniPrimary (citable) accession number: Q9DER6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 4, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.