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Protein
Submitted name:

Cytochrome P450 3A

Gene

CYP3A

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 3AImported
Gene namesi
Name:CYP3AImported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 30HelicalSequence analysisAdd BLAST19
Transmembranei215 – 233HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ9DE99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG108567.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9DE99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNFLYFSAE TWTLLVAFIT LLLVYAYWPY GTFKRLGIPG PKPVPFFGTM
60 70 80 90 100
LAYRKGFPIF DEECHKKYGK TWGIYDGRQP VLCITDPATI KAVLVKECYS
110 120 130 140 150
LFTNRRNFHL NGPMYDSVFN AEDDQWKRIR SVLSPSFTSG RLKEMFDIMK
160 170 180 190 200
HHSANLVNSM KKKADKDEPL NLKDHFGPYS MDVVTSTAFS VDIDSLNNPS
210 220 230 240 250
DPFVTNIKKM LKFDFLNPLF LLVAFFPFLG PIMEKMELSF FPASAFDFFY
260 270 280 290 300
SALQKIKSDH KNNKQKSRID FLQLMIDSQK NNQNGLQDKG LSDHEILSQA
310 320 330 340 350
MIFIFAGYET TSSSLTFLAY NLATNPEVMK KLQKEIDATF PNKAPIQYAP
360 370 380 390 400
LLEMEYLDSV VNESLRLYPI AARLERVAKA TVEVNGLVIP KDMVVMVPTW
410 420 430 440 450
PIQRDPELWP EPEKFKPERF SKETKETFDP YTYMPFGAGP RNCIGMRFAL
460 470 480 490 500
VSMKLALVEI LQQYSFSVCK ETEIPFELDI QGLIAPKRPI FLKLVPRSAC
Length:500
Mass (Da):57,382
Last modified:March 1, 2001 - v1
Checksum:iEB0A8479601CE8C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF105018 mRNA. Translation: AAG35209.1.
RefSeqiNP_001292334.1. NM_001305405.1.
XP_004085708.2. XM_004085660.2.
UniGeneiOla.18272.

Genome annotation databases

GeneIDi101155406.
KEGGiola:101155406.

Similar proteinsi

Entry informationi

Entry nameiQ9DE99_ORYLA
AccessioniPrimary (citable) accession number: Q9DE99
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 27, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)