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Protein
Submitted name:

Paracaspase

Gene

malt1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ParacaspaseImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:malt1aImported
Synonyms:malt1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 22

Organism-specific databases

ZFINiZDB-GENE-020801-2. malt1a.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000020264.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini104 – 18077Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini203 – 28987Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini321 – 448128CASPASE_P20InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IG3U. Eukaryota.
COG4249. LUCA.
GeneTreeiENSGT00390000018044.
HOGENOMiHOG000113471.
HOVERGENiHBG052402.
KOiK07369.
OMAiITRGRQA.
OrthoDBiEOG7673BH.
TreeFamiTF319744.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.60.40.10. 2 hits.
3.40.50.1460. 1 hit.
InterProiIPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR001309. Pept_C14_p20.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF48726. SSF48726. 2 hits.
SSF52129. SSF52129. 1 hit.
PROSITEiPS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DDL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKNLGLEN ISEAALSRLG YMLDNAECGW KQLAKAVAEQ PQFCYSDREM
60 70 80 90 100
TDCSLKVLSP HGSPGRYLLA LLADRGCTLA FLLQCLKKIE HREAVGFLTM
110 120 130 140 150
NVMEQIDIIQ QPQSQRIAEG SPVVLSCKAV GPVELQYQWF KGKDEMPEGN
160 170 180 190 200
SPDLVFNRAS PAQQGYYICR VSSGDKYIFS NWAHVYLLRS GGASADSSSS
210 220 230 240 250
YFPSTASGLN ITQQPRPQAL MEGDTLCLEC SAQANPPPQF QWYFNKELMP
260 270 280 290 300
KCIRNFLKIP CITTADRGIY ACRVYNLYHE MWSDQVQVNI GPGSCSESSW
310 320 330 340 350
EKTAVDNPEA NLKQMGDCCA TDKVALLIGN MNYLHHRQLR APMADVHELT
360 370 380 390 400
NLLRQLDFKV VSLLDLNWQE MHSAVTEFLL LLDRGVYGLL YFAGHGYENY
410 420 430 440 450
GNSFMVPIDA PASYTFKHCL WVQEVLQRMQ ERQTGLNVFL LDMCRKRNPN
460 470 480 490 500
DEGIPQPDPL RVTANIVFGY ATCVDAEAFE VNKDDLSNGI FMSFLKKRLM
510 520 530 540 550
EPEKVTVILD KVAEDMGRCE ITRGRQALEL RSNLSERRAL TDKIQAPACQ
560 570 580 590 600
IAASTRNLQW AIAHVLPESR CLQFECGVTV QLGFAAEFSN IMIIYTQILE
610 620 630 640 650
TPTDIVSCSA QLSDFTEGPE VDLKRSNQES LHEAESFLLT IDDLLPLKQP
660 670 680 690 700
QLFTRISALQ RLKKELSFTV CLHYKYGNLD EELLEEKRIT VGKPLVSKLN
710 720 730 740 750
LHEPRLFHSS SSDQQMSSFL DSSSFSESFR ANLPDLKQNF IGSASTSLPN
760 770 780 790 800
YRVPMESFAC FGLKNEPEET LCPEFLESEE PPAIKSLPSA SSEELPFKFS

NFQNSI
Length:806
Mass (Da):90,754
Last modified:March 1, 2001 - v1
Checksum:i589A8BC2013B0A51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323550 Genomic DNA. No translation available.
AF316598 mRNA. Translation: AAG38590.1.
RefSeqiNP_694508.1. NM_152976.1.
UniGeneiDr.77507.

Genome annotation databases

EnsembliENSDART00000008424; ENSDARP00000020264; ENSDARG00000006052.
GeneIDi259196.
KEGGidre:259196.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323550 Genomic DNA. No translation available.
AF316598 mRNA. Translation: AAG38590.1.
RefSeqiNP_694508.1. NM_152976.1.
UniGeneiDr.77507.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000020264.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000008424; ENSDARP00000020264; ENSDARG00000006052.
GeneIDi259196.
KEGGidre:259196.

Organism-specific databases

CTDi259196.
ZFINiZDB-GENE-020801-2. malt1a.

Phylogenomic databases

eggNOGiENOG410IG3U. Eukaryota.
COG4249. LUCA.
GeneTreeiENSGT00390000018044.
HOGENOMiHOG000113471.
HOVERGENiHBG052402.
KOiK07369.
OMAiITRGRQA.
OrthoDBiEOG7673BH.
TreeFamiTF319744.

Miscellaneous databases

NextBioi20804706.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.60.40.10. 2 hits.
3.40.50.1460. 1 hit.
InterProiIPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR001309. Pept_C14_p20.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF48726. SSF48726. 2 hits.
SSF52129. SSF52129. 1 hit.
PROSITEiPS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of paracaspases and metacaspases. Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma."
    Uren A.G., O'Rourke K., Aravind L., Pisabarro M.T., Seshagiri S., Koonin E.V., Dixit V.M.
    Mol. Cell 6:961-967(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  3. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ9DDL2_DANRE
AccessioniPrimary (citable) accession number: Q9DDL2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 11, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.