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Q9DDD5

- NBEA_CHICK

UniProt

Q9DDD5 - NBEA_CHICK

Protein

Neurobeachin

Gene

NBEA

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins By similarity.By similarity

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Neurobeachin
    Gene namesi
    Name:NBEA
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Unplaced

    Subcellular locationi

    Cytoplasm By similarity. Membrane By similarity; Peripheral membrane protein By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›793›793NeurobeachinPRO_0000051091Add
    BLAST

    Proteomic databases

    PaxDbiQ9DDD5.
    PRIDEiQ9DDD5.

    Expressioni

    Tissue specificityi

    Forebrain and cerebellum.1 Publication

    Interactioni

    Subunit structurei

    Interacts with RII subunit of PKA.By similarity

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000027505.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the WD repeat neurobeachin family.Curated

    Phylogenomic databases

    eggNOGiNOG236271.
    PhylomeDBiQ9DDD5.

    Sequencei

    Sequence statusi: Fragment.

    Q9DDD5-1 [UniParc]FASTAAdd to Basket

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    PKNSEEQKIT EMVYNIFRIL LYHAIKYEWG GWRVWVDTLS IAHSKVTYEA    50
    HKEYLAKMYE EYQRQEEENI KKGKKGNVST ISGLSSQTTG AKGGMEIREI 100
    EDLSQSQSPE SETDYPVSTD TRDLLMATKV SDDVLGSAER PGGGVHVEVH 150
    DLLVDIKAER VEATEVKLDD MDLSPETLVT GENGALVEVE SLLDNVYSAA 200
    VEKLQNSVHG SVGIIKKNEE KDGGPLITLA DEKDEPSTNS TSFLFDKIPS 250
    QEEKLLPDLS ISHISIPNVQ DTQMHLGVND DLGLLAHMTG GVDITSTSSI 300
    IEDKEFKIHT NSVGMSSIFE RELASLFKGL EYAEMTATTP ETEFFCSKTV 350
    PNVDAGSIIS VTERFVDGKE AGKEIRKIQT TTTTQAVQGR SVTQQDRDLR 400
    VDLGFRGMPM TEEQRRQFSP GPRTNMFRIP EFKWSPMHQR LLTDLLFALE 450
    TDVHVWRSHS TKSVMDFVNS NENIIFVHNT IHLISQMVDN IIIACGGILP 500
    LLSAATSPTG SKTELENIEV TQGMSAETAV TFLSRLMAMV DVLVFASSLN 550
    FSEIEAEKNM SSGGLMRQCL RLVCCVAVRN CLECRQRQRE RVNKTSLISS 600
    KAQDALQGVT ASAATKTPLE NVPGNLSPIK DPDRLLQDVD INRLRAVVFR 650
    DVDDSKQAQF LALAVVYFIS VLMVSKYRDI LEPQRETARS GSQAGRNIRQ 700
    EINSPTSTET PAVFPENIKD KETPTPVEDI QLESSIPHTD SGIGEEQMPN 750
    ILNGTDLETS TGPDAMSELL STLSSEVKKS QESLTESPSE ILK 793
    Length:793
    Mass (Da):87,803
    Last modified:March 1, 2001 - v1
    Checksum:i19F5AC6C49A7F2A2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei793 – 7931Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y18277 mRNA. Translation: CAC18801.1.
    UniGeneiGga.18.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y18277 mRNA. Translation: CAC18801.1 .
    UniGenei Gga.18.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000027505.

    Proteomic databases

    PaxDbi Q9DDD5.
    PRIDEi Q9DDD5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG236271.
    PhylomeDBi Q9DDD5.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic."
      Wang X., Herberg F.W., Laue M.M., Wullner C., Hu B., Petrasch-Parwez E., Kilimann M.W.
      J. Neurosci. 20:8551-8565(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiNBEA_CHICK
    AccessioniPrimary (citable) accession number: Q9DDD5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 20, 2003
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3