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Q9DDD5

- NBEA_CHICK

UniProt

Q9DDD5 - NBEA_CHICK

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Protein
Neurobeachin
Gene
NBEA
Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins By similarity.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Neurobeachin
Gene namesi
Name:NBEA
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Unplaced

Subcellular locationi

Cytoplasm By similarity. Membrane; Peripheral membrane protein By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›793›793Neurobeachin
PRO_0000051091Add
BLAST

Proteomic databases

PaxDbiQ9DDD5.
PRIDEiQ9DDD5.

Expressioni

Tissue specificityi

Forebrain and cerebellum.1 Publication

Interactioni

Subunit structurei

Interacts with RII subunit of PKA By similarity.By similarity

Protein-protein interaction databases

STRINGi9031.ENSGALP00000027505.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG236271.
PhylomeDBiQ9DDD5.

Sequencei

Sequence statusi: Fragment.

Q9DDD5-1 [UniParc]FASTAAdd to Basket

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PKNSEEQKIT EMVYNIFRIL LYHAIKYEWG GWRVWVDTLS IAHSKVTYEA    50
HKEYLAKMYE EYQRQEEENI KKGKKGNVST ISGLSSQTTG AKGGMEIREI 100
EDLSQSQSPE SETDYPVSTD TRDLLMATKV SDDVLGSAER PGGGVHVEVH 150
DLLVDIKAER VEATEVKLDD MDLSPETLVT GENGALVEVE SLLDNVYSAA 200
VEKLQNSVHG SVGIIKKNEE KDGGPLITLA DEKDEPSTNS TSFLFDKIPS 250
QEEKLLPDLS ISHISIPNVQ DTQMHLGVND DLGLLAHMTG GVDITSTSSI 300
IEDKEFKIHT NSVGMSSIFE RELASLFKGL EYAEMTATTP ETEFFCSKTV 350
PNVDAGSIIS VTERFVDGKE AGKEIRKIQT TTTTQAVQGR SVTQQDRDLR 400
VDLGFRGMPM TEEQRRQFSP GPRTNMFRIP EFKWSPMHQR LLTDLLFALE 450
TDVHVWRSHS TKSVMDFVNS NENIIFVHNT IHLISQMVDN IIIACGGILP 500
LLSAATSPTG SKTELENIEV TQGMSAETAV TFLSRLMAMV DVLVFASSLN 550
FSEIEAEKNM SSGGLMRQCL RLVCCVAVRN CLECRQRQRE RVNKTSLISS 600
KAQDALQGVT ASAATKTPLE NVPGNLSPIK DPDRLLQDVD INRLRAVVFR 650
DVDDSKQAQF LALAVVYFIS VLMVSKYRDI LEPQRETARS GSQAGRNIRQ 700
EINSPTSTET PAVFPENIKD KETPTPVEDI QLESSIPHTD SGIGEEQMPN 750
ILNGTDLETS TGPDAMSELL STLSSEVKKS QESLTESPSE ILK 793
Length:793
Mass (Da):87,803
Last modified:March 1, 2001 - v1
Checksum:i19F5AC6C49A7F2A2
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei793 – 7931

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y18277 mRNA. Translation: CAC18801.1.
UniGeneiGga.18.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y18277 mRNA. Translation: CAC18801.1 .
UniGenei Gga.18.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000027505.

Proteomic databases

PaxDbi Q9DDD5.
PRIDEi Q9DDD5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG236271.
PhylomeDBi Q9DDD5.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic."
    Wang X., Herberg F.W., Laue M.M., Wullner C., Hu B., Petrasch-Parwez E., Kilimann M.W.
    J. Neurosci. 20:8551-8565(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Tissue: Brain.

Entry informationi

Entry nameiNBEA_CHICK
AccessioniPrimary (citable) accession number: Q9DDD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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