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Protein

Stromal cell-derived factor 2

Gene

Sdf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Stromal cell-derived factor 2
Short name:
SDF-2
Gene namesi
Name:Sdf2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:108019. Sdf2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence analysisAdd
BLAST
Chaini19 – 211193Stromal cell-derived factor 2PRO_0000031956Add
BLAST

Proteomic databases

EPDiQ9DCT5.
MaxQBiQ9DCT5.
PaxDbiQ9DCT5.
PeptideAtlasiQ9DCT5.
PRIDEiQ9DCT5.

PTM databases

PhosphoSiteiQ9DCT5.

Expressioni

Tissue specificityi

Ubiquitously expressed with highest expression in liver and kidney.

Gene expression databases

BgeeiENSMUSG00000002064.
CleanExiMM_SDF2.

Interactioni

Protein-protein interaction databases

IntActiQ9DCT5. 1 interaction.
MINTiMINT-1851573.
STRINGi10090.ENSMUSP00000002133.

Structurei

3D structure databases

ProteinModelPortaliQ9DCT5.
SMRiQ9DCT5. Positions 18-194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 7555MIR 1PROSITE-ProRule annotationAdd
BLAST
Domaini83 – 13856MIR 2PROSITE-ProRule annotationAdd
BLAST
Domaini139 – 19355MIR 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 MIR domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG3358. Eukaryota.
ENOG410ZBU3. LUCA.
HOGENOMiHOG000236354.
HOVERGENiHBG024385.
InParanoidiQ9DCT5.
PhylomeDBiQ9DCT5.
TreeFamiTF314557.

Family and domain databases

InterProiIPR027005. GlyclTrfase_39-like.
IPR016093. MIR_motif.
[Graphical view]
PANTHERiPTHR10050. PTHR10050. 1 hit.
PfamiPF02815. MIR. 1 hit.
[Graphical view]
SMARTiSM00472. MIR. 3 hits.
[Graphical view]
SUPFAMiSSF82109. SSF82109. 1 hit.
PROSITEiPS50919. MIR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9DCT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVLSLLLLG GLWSAVGASN MAVVTCGSVV KLLNTRHNVR LHSHDVRYGS
60 70 80 90 100
GSGQQSVTGV TSVDDSNSYW RIRGKTATVC ERGTPIKCGQ PIRLTHINTG
110 120 130 140 150
RNLHSHHFTS PLSGNQEVSA FGEEGEGDYL DDWTVLCNGP YWVRDGEVRF
160 170 180 190 200
KHSSTDVLLS VTGEQYGRPI SGQKEVHGMA QPSQNNYWKA MEGIFMKPSE
210
LLRAEVHHAE L
Length:211
Mass (Da):23,159
Last modified:June 1, 2001 - v1
Checksum:i9BC16CB12A79DCF5
GO

Sequence cautioni

The sequence BAB22144 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti120 – 1201A → S in BAA09313 (PubMed:8918255).Curated
Sequence conflicti138 – 1381N → I in BAA09313 (PubMed:8918255).Curated
Sequence conflicti174 – 1741K → Q in BAA09313 (PubMed:8918255).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50646 mRNA. Translation: BAA09313.1.
AK002496 mRNA. Translation: BAB22144.2. Different initiation.
BC058798 mRNA. Translation: AAH58798.1.
PIRiJC5105.
RefSeqiNP_033169.3. NM_009143.3.
UniGeneiMm.20755.
Mm.390372.

Genome annotation databases

GeneIDi20316.
KEGGimmu:20316.
UCSCiuc007kiq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50646 mRNA. Translation: BAA09313.1.
AK002496 mRNA. Translation: BAB22144.2. Different initiation.
BC058798 mRNA. Translation: AAH58798.1.
PIRiJC5105.
RefSeqiNP_033169.3. NM_009143.3.
UniGeneiMm.20755.
Mm.390372.

3D structure databases

ProteinModelPortaliQ9DCT5.
SMRiQ9DCT5. Positions 18-194.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9DCT5. 1 interaction.
MINTiMINT-1851573.
STRINGi10090.ENSMUSP00000002133.

PTM databases

PhosphoSiteiQ9DCT5.

Proteomic databases

EPDiQ9DCT5.
MaxQBiQ9DCT5.
PaxDbiQ9DCT5.
PeptideAtlasiQ9DCT5.
PRIDEiQ9DCT5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20316.
KEGGimmu:20316.
UCSCiuc007kiq.2. mouse.

Organism-specific databases

CTDi6388.
MGIiMGI:108019. Sdf2.

Phylogenomic databases

eggNOGiKOG3358. Eukaryota.
ENOG410ZBU3. LUCA.
HOGENOMiHOG000236354.
HOVERGENiHBG024385.
InParanoidiQ9DCT5.
PhylomeDBiQ9DCT5.
TreeFamiTF314557.

Miscellaneous databases

PROiQ9DCT5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002064.
CleanExiMM_SDF2.

Family and domain databases

InterProiIPR027005. GlyclTrfase_39-like.
IPR016093. MIR_motif.
[Graphical view]
PANTHERiPTHR10050. PTHR10050. 1 hit.
PfamiPF02815. MIR. 1 hit.
[Graphical view]
SMARTiSM00472. MIR. 3 hits.
[Graphical view]
SUPFAMiSSF82109. SSF82109. 1 hit.
PROSITEiPS50919. MIR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSDF2_MOUSE
AccessioniPrimary (citable) accession number: Q9DCT5
Secondary accession number(s): P97307
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.