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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

Gene

Ndufb10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105. Respiratory electron transport.
R-MMU-6799198. Complex I biogenesis.

Protein family/group databases

TCDBi3.D.1.6.1. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Alternative name(s):
Complex I-PDSW
Short name:
CI-PDSW
NADH-ubiquinone oxidoreductase PDSW subunit
Gene namesi
Name:Ndufb10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1915592. Ndufb10.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: MGI
  • mitochondrial inner membrane Source: MGI
  • mitochondrial respiratory chain complex I Source: MGI
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10PRO_0000118831Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei21 – 211PhosphoserineCombined sources
Modified residuei151 – 1511PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9DCS9.
MaxQBiQ9DCS9.
PaxDbiQ9DCS9.
PeptideAtlasiQ9DCS9.
PRIDEiQ9DCS9.

PTM databases

iPTMnetiQ9DCS9.
PhosphoSiteiQ9DCS9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000040048.
ExpressionAtlasiQ9DCS9. baseline and differential.
GenevisibleiQ9DCS9. MM.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

BioGridi212811. 1 interaction.
IntActiQ9DCS9. 3 interactions.
MINTiMINT-1861021.
STRINGi10090.ENSMUSP00000043543.

Structurei

3D structure databases

ProteinModelPortaliQ9DCS9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB10 subunit family.Curated

Phylogenomic databases

eggNOGiKOG4009. Eukaryota.
ENOG4111MMM. LUCA.
GeneTreeiENSGT00390000006348.
HOGENOMiHOG000090968.
HOVERGENiHBG003196.
InParanoidiQ9DCS9.
KOiK03966.
OMAiITECKEK.
OrthoDBiEOG091G1BQN.
PhylomeDBiQ9DCS9.
TreeFamiTF105792.

Family and domain databases

InterProiIPR019377. NADH_UbQ_OxRdtase_su10.
[Graphical view]
PfamiPF10249. NDUFB10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DCS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDSWDKDVY PEPPSRTPAP SPQTSLPNPI TYLTKAYDLV VDWPVTLVRE
60 70 80 90 100
FIERQHAKNR TYYYHRQYRR VPDITECKEG DVLCIYEAEM QWRRDFKVDQ
110 120 130 140 150
EIMNIIQERL KACQQREGEN YQQNCAKELE QFTKVTKAYQ DRYLDLGAYY
160 170
SARKCLAKQK QRMLEERKAA RQEAAA
Length:176
Mass (Da):21,024
Last modified:January 23, 2007 - v3
Checksum:i1A3BA32E0F8551C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002517 mRNA. Translation: BAB22156.1.
AK151404 mRNA. Translation: BAE30371.1.
BC031664 mRNA. Translation: AAH31664.1.
BC043013 mRNA. Translation: AAH43013.1.
CCDSiCCDS28494.1.
RefSeqiNP_080960.1. NM_026684.2.
UniGeneiMm.1129.

Genome annotation databases

EnsembliENSMUST00000045602; ENSMUSP00000043543; ENSMUSG00000040048.
GeneIDi68342.
KEGGimmu:68342.
UCSCiuc008ayd.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002517 mRNA. Translation: BAB22156.1.
AK151404 mRNA. Translation: BAE30371.1.
BC031664 mRNA. Translation: AAH31664.1.
BC043013 mRNA. Translation: AAH43013.1.
CCDSiCCDS28494.1.
RefSeqiNP_080960.1. NM_026684.2.
UniGeneiMm.1129.

3D structure databases

ProteinModelPortaliQ9DCS9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212811. 1 interaction.
IntActiQ9DCS9. 3 interactions.
MINTiMINT-1861021.
STRINGi10090.ENSMUSP00000043543.

Protein family/group databases

TCDBi3.D.1.6.1. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

PTM databases

iPTMnetiQ9DCS9.
PhosphoSiteiQ9DCS9.

Proteomic databases

EPDiQ9DCS9.
MaxQBiQ9DCS9.
PaxDbiQ9DCS9.
PeptideAtlasiQ9DCS9.
PRIDEiQ9DCS9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000045602; ENSMUSP00000043543; ENSMUSG00000040048.
GeneIDi68342.
KEGGimmu:68342.
UCSCiuc008ayd.1. mouse.

Organism-specific databases

CTDi4716.
MGIiMGI:1915592. Ndufb10.

Phylogenomic databases

eggNOGiKOG4009. Eukaryota.
ENOG4111MMM. LUCA.
GeneTreeiENSGT00390000006348.
HOGENOMiHOG000090968.
HOVERGENiHBG003196.
InParanoidiQ9DCS9.
KOiK03966.
OMAiITECKEK.
OrthoDBiEOG091G1BQN.
PhylomeDBiQ9DCS9.
TreeFamiTF105792.

Enzyme and pathway databases

ReactomeiR-MMU-611105. Respiratory electron transport.
R-MMU-6799198. Complex I biogenesis.

Miscellaneous databases

ChiTaRSiNdufb10. mouse.
PROiQ9DCS9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040048.
ExpressionAtlasiQ9DCS9. baseline and differential.
GenevisibleiQ9DCS9. MM.

Family and domain databases

InterProiIPR019377. NADH_UbQ_OxRdtase_su10.
[Graphical view]
PfamiPF10249. NDUFB10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNDUBA_MOUSE
AccessioniPrimary (citable) accession number: Q9DCS9
Secondary accession number(s): Q3UAE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 110 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.