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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

Gene

Ndufb10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105 Respiratory electron transport
R-MMU-6799198 Complex I biogenesis

Protein family/group databases

TCDBi3.D.1.6.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Alternative name(s):
Complex I-PDSW
Short name:
CI-PDSW
NADH-ubiquinone oxidoreductase PDSW subunit
Gene namesi
Name:Ndufb10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1915592 Ndufb10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001188311 – 176NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10Add BLAST176

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei21PhosphoserineCombined sources1
Modified residuei151PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9DCS9
MaxQBiQ9DCS9
PaxDbiQ9DCS9
PeptideAtlasiQ9DCS9
PRIDEiQ9DCS9

PTM databases

iPTMnetiQ9DCS9
PhosphoSitePlusiQ9DCS9

Expressioni

Gene expression databases

BgeeiENSMUSG00000040048
ExpressionAtlasiQ9DCS9 baseline and differential
GenevisibleiQ9DCS9 MM

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

BioGridi212811, 1 interactor
CORUMiQ9DCS9
IntActiQ9DCS9, 3 interactors
MINTiQ9DCS9
STRINGi10090.ENSMUSP00000043543

Structurei

3D structure databases

ProteinModelPortaliQ9DCS9
SMRiQ9DCS9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB10 subunit family.Curated

Phylogenomic databases

eggNOGiKOG4009 Eukaryota
ENOG4111MMM LUCA
GeneTreeiENSGT00390000006348
HOGENOMiHOG000090968
HOVERGENiHBG003196
InParanoidiQ9DCS9
KOiK03966
OMAiAYQDRYQ
OrthoDBiEOG091G1BQN
PhylomeDBiQ9DCS9
TreeFamiTF105792

Family and domain databases

InterProiView protein in InterPro
IPR019377 NADH_UbQ_OxRdtase_su10
PfamiView protein in Pfam
PF10249 NDUFB10, 1 hit

Sequencei

Sequence statusi: Complete.

Q9DCS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDSWDKDVY PEPPSRTPAP SPQTSLPNPI TYLTKAYDLV VDWPVTLVRE
60 70 80 90 100
FIERQHAKNR TYYYHRQYRR VPDITECKEG DVLCIYEAEM QWRRDFKVDQ
110 120 130 140 150
EIMNIIQERL KACQQREGEN YQQNCAKELE QFTKVTKAYQ DRYLDLGAYY
160 170
SARKCLAKQK QRMLEERKAA RQEAAA
Length:176
Mass (Da):21,024
Last modified:January 23, 2007 - v3
Checksum:i1A3BA32E0F8551C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002517 mRNA Translation: BAB22156.1
AK151404 mRNA Translation: BAE30371.1
BC031664 mRNA Translation: AAH31664.1
BC043013 mRNA Translation: AAH43013.1
CCDSiCCDS28494.1
RefSeqiNP_080960.1, NM_026684.2
UniGeneiMm.1129

Genome annotation databases

EnsembliENSMUST00000045602; ENSMUSP00000043543; ENSMUSG00000040048
GeneIDi68342
KEGGimmu:68342
UCSCiuc008ayd.1 mouse

Similar proteinsi

Entry informationi

Entry nameiNDUBA_MOUSE
AccessioniPrimary (citable) accession number: Q9DCS9
Secondary accession number(s): Q3UAE3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 119 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health