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Protein

Vesicle transport protein GOT1A

Gene

Golt1a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in fusion of ER-derived transport vesicles with the Golgi complex.By similarity

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle transport protein GOT1A
Alternative name(s):
Golgi transport 1 homolog A
Gene namesi
Name:Golt1aImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1915588. Golt1a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9CytoplasmicSequence analysis9
Transmembranei10 – 30Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini31LumenalSequence analysis1
Transmembranei32 – 52Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini53 – 68CytoplasmicSequence analysisAdd BLAST16
Transmembranei69 – 89Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini90 – 92LumenalSequence analysis3
Transmembranei93 – 113Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini114 – 133CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002376081 – 133Vesicle transport protein GOT1AAdd BLAST133

Proteomic databases

MaxQBiQ9DCQ3.
PaxDbiQ9DCQ3.
PRIDEiQ9DCQ3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000098306.
ExpressionAtlasiQ9DCQ3. baseline and differential.
GenevisibleiQ9DCQ3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000092136.

Family & Domainsi

Sequence similaritiesi

Belongs to the GOT1 family.Sequence analysis

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1743. Eukaryota.
COG5120. LUCA.
GeneTreeiENSGT00390000014507.
HOGENOMiHOG000035939.
HOVERGENiHBG009362.
InParanoidiQ9DCQ3.
OMAiKTFWFFF.
OrthoDBiEOG091G10MS.
PhylomeDBiQ9DCQ3.
TreeFamiTF300267.

Family and domain databases

InterProiView protein in InterPro
IPR007305. Vesicle_transpt_Got1/SFT2.
PfamiView protein in Pfam
PF04178. Got1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9DCQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISITEWQKI GVGITGFGVF FILFGILLYF DSVLLAFGNL LFLTGLSLII
60 70 80 90 100
GLRRTFAFFF QRHKLKGTSF FLGGVAIVLL RWPLLGMLLE AYGFISLFKG
110 120 130
FFPVVFGFLG SAFNIPFLST LFQKLQGSSS SMV
Length:133
Mass (Da):14,800
Last modified:June 1, 2001 - v1
Checksum:i32ACEC0D779C40D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY707855 mRNA. Translation: AAW34128.1.
AY707856 mRNA. Translation: AAW34129.1.
AK002581 mRNA. Translation: BAB22205.1.
AK141378 mRNA. Translation: BAE24665.1.
BC024448 mRNA. Translation: AAH24448.1.
CCDSiCCDS35709.1.
RefSeqiNP_080956.1. NM_026680.4.
UniGeneiMm.247935.

Genome annotation databases

EnsembliENSMUST00000094557; ENSMUSP00000092136; ENSMUSG00000103421.
ENSMUST00000183489; ENSMUSP00000139189; ENSMUSG00000098306.
GeneIDi68338.
KEGGimmu:68338.
UCSCiuc007cqa.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiGOT1A_MOUSE
AccessioniPrimary (citable) accession number: Q9DCQ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2001
Last modified: September 27, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families