Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease P protein subunit p20

Gene

Pop7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p20 (EC:3.1.26.5)
Short name:
RNaseP protein p20
Gene namesi
Name:Pop7
Synonyms:Rpp20
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1921347. Pop7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 140140Ribonuclease P protein subunit p20PRO_0000237701Add
BLAST

Proteomic databases

EPDiQ9DCH2.
MaxQBiQ9DCH2.
PaxDbiQ9DCH2.
PeptideAtlasiQ9DCH2.
PRIDEiQ9DCH2.

PTM databases

PhosphoSiteiQ9DCH2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029715.
GenevisibleiQ9DCH2. MM.

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and SMN1. RPP20/POP7 is probably a dimer (By similarity).By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031728.

Structurei

3D structure databases

ProteinModelPortaliQ9DCH2.
SMRiQ9DCH2. Positions 35-136.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like Alba family.Curated

Phylogenomic databases

eggNOGiENOG410IXMT. Eukaryota.
ENOG4111R36. LUCA.
GeneTreeiENSGT00510000048483.
HOGENOMiHOG000253010.
HOVERGENiHBG001490.
InParanoidiQ9DCH2.
KOiK14527.
OMAiGQNACTE.
OrthoDBiEOG091G0Y8P.
PhylomeDBiQ9DCH2.
TreeFamiTF313948.

Family and domain databases

Gene3Di3.30.110.20. 1 hit.
InterProiIPR002775. DNA/RNA-bd_Alba-like.
IPR014612. Pop7/Rpp20.
[Graphical view]
PANTHERiPTHR15314. PTHR15314. 1 hit.
PfamiPF12328. Rpp20. 1 hit.
[Graphical view]
PIRSFiPIRSF036572. RPP20. 1 hit.
SUPFAMiSSF82704. SSF82704. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9DCH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAENREPRCA IEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA
60 70 80 90 100
RCQKLLDGGT RGQNACTEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA
110 120 130 140
NTSTVELVDE LEPETDSREP LTRVRNNSAI HIRVFRVTPK
Length:140
Mass (Da):15,777
Last modified:June 1, 2001 - v1
Checksum:i0F30841C7F50DFA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312033 Genomic DNA. Translation: AAK28826.1.
AK002782 mRNA. Translation: BAB22355.1.
AK158620 mRNA. Translation: BAE34584.1.
AK162268 mRNA. Translation: BAE36826.1.
BC010780 mRNA. Translation: AAH10780.1.
CCDSiCCDS19768.1.
RefSeqiNP_083029.1. NM_028753.2.
UniGeneiMm.290242.

Genome annotation databases

EnsembliENSMUST00000031728; ENSMUSP00000031728; ENSMUSG00000029715.
ENSMUST00000111035; ENSMUSP00000106664; ENSMUSG00000029715.
GeneIDi74097.
KEGGimmu:74097.
UCSCiuc009aco.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312033 Genomic DNA. Translation: AAK28826.1.
AK002782 mRNA. Translation: BAB22355.1.
AK158620 mRNA. Translation: BAE34584.1.
AK162268 mRNA. Translation: BAE36826.1.
BC010780 mRNA. Translation: AAH10780.1.
CCDSiCCDS19768.1.
RefSeqiNP_083029.1. NM_028753.2.
UniGeneiMm.290242.

3D structure databases

ProteinModelPortaliQ9DCH2.
SMRiQ9DCH2. Positions 35-136.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031728.

PTM databases

PhosphoSiteiQ9DCH2.

Proteomic databases

EPDiQ9DCH2.
MaxQBiQ9DCH2.
PaxDbiQ9DCH2.
PeptideAtlasiQ9DCH2.
PRIDEiQ9DCH2.

Protocols and materials databases

DNASUi74097.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031728; ENSMUSP00000031728; ENSMUSG00000029715.
ENSMUST00000111035; ENSMUSP00000106664; ENSMUSG00000029715.
GeneIDi74097.
KEGGimmu:74097.
UCSCiuc009aco.1. mouse.

Organism-specific databases

CTDi10248.
MGIiMGI:1921347. Pop7.

Phylogenomic databases

eggNOGiENOG410IXMT. Eukaryota.
ENOG4111R36. LUCA.
GeneTreeiENSGT00510000048483.
HOGENOMiHOG000253010.
HOVERGENiHBG001490.
InParanoidiQ9DCH2.
KOiK14527.
OMAiGQNACTE.
OrthoDBiEOG091G0Y8P.
PhylomeDBiQ9DCH2.
TreeFamiTF313948.

Miscellaneous databases

PROiQ9DCH2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029715.
GenevisibleiQ9DCH2. MM.

Family and domain databases

Gene3Di3.30.110.20. 1 hit.
InterProiIPR002775. DNA/RNA-bd_Alba-like.
IPR014612. Pop7/Rpp20.
[Graphical view]
PANTHERiPTHR15314. PTHR15314. 1 hit.
PfamiPF12328. Rpp20. 1 hit.
[Graphical view]
PIRSFiPIRSF036572. RPP20. 1 hit.
SUPFAMiSSF82704. SSF82704. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPOP7_MOUSE
AccessioniPrimary (citable) accession number: Q9DCH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.