Q9DCG9 (TR112_MOUSE) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 67.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: tRNA methyltransferase 112 homolog Alternative name(s): TRM112-like protein | ||
| Gene names |
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| Organism | Mus musculus (Mouse) | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus |
Protein attributes
| Sequence length | 125 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species By similarity. |
| Subunit structure | Interacts with ALKBH8 and HEMK2/N6AMT1 By similarity. |
| Sequence similarities | Belongs to the TRM112 family. Contains 1 TRM112 domain. |
Ontologies
| Keywords | |
|---|---|
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| None. [Check GOA] | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Embryo and Kidney. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AK002791 mRNA. Translation: BAB22361.1. AK003292 mRNA. Translation: BAB22695.1. BC016191 mRNA. Translation: AAH16191.1. |
| IPI | IPI00120871. |
| RefSeq | NP_001159842.1. NM_001166370.1. NP_080582.3. NM_026306.3. XP_003086453.1. XM_003086405.1. XP_897794.1. XM_892701.4. |
| UniGene | Mm.318804. Mm.371597. |
3D structure databases | |
| ProteinModelPortal | Q9DCG9. |
| SMR | Q9DCG9. Positions 1-124. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9DCG9. |
PTM databases | |
| PhosphoSite | Q9DCG9. |
Proteomic databases | |
| PRIDE | Q9DCG9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUST00000088257; ENSMUSP00000085591; ENSMUSG00000038812. ENSMUST00000116551; ENSMUSP00000112250; ENSMUSG00000038812. |
| GeneID | 100503161. 627985. 67674. |
| KEGG | mmu:100503161. mmu:627985. mmu:67674. |
| UCSC | uc008gjd.2. mouse. |
Organism-specific databases | |
| CTD | 51504. |
| MGI | MGI:1914924. Trmt112. |
Phylogenomic databases | |
| GeneTree | ENSGT00390000009268. |
| HOGENOM | HBG526194. |
| HOVERGEN | HBG056590. |
| InParanoid | Q9DCG9. |
| OMA | RLLTHNM. |
| OrthoDB | EOG4WQ140. |
| PhylomeDB | Q9DCG9. |
Gene expression databases | |
| ArrayExpress | Q9DCG9. |
| Bgee | Q9DCG9. |
| CleanEx | MM_0610038D11RIK. |
| Genevestigator | Q9DCG9. |
| GermOnline | ENSMUSG00000038812. Mus musculus. ENSMUSG00000070572. Mus musculus. |
Family and domain databases | |
| InterPro | IPR005651. UPF0434/Trm112. [Graphical view] |
| KO | K15448. |
| Pfam | PF03966. Trm112p. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 420118. |
| SOURCE | Search... |
Entry information
| Entry name | TR112_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q9DCG9 Secondary accession number(s): Q91YP8, Q9D1N6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with