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Q9DBS6

- Q9DBS6_MOUSE

UniProt

Q9DBS6 - Q9DBS6_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Pde1b

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 3',5'-cyclic-AMP phosphodiesterase activity Source: Ensembl
    2. calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity Source: MGI
    3. calmodulin-dependent cyclic-nucleotide phosphodiesterase activity Source: MGI
    4. cyclic-nucleotide phosphodiesterase activity Source: MGI
    5. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cAMP catabolic process Source: Ensembl
    2. cellular response to granulocyte macrophage colony-stimulating factor stimulus Source: Ensembl
    3. cellular response to macrophage colony-stimulating factor stimulus Source: Ensembl
    4. cGMP catabolic process Source: Ensembl
    5. locomotory behavior Source: MGI
    6. monocyte differentiation Source: Ensembl
    7. regulation of dopamine metabolic process Source: MGI
    8. regulation of neurotransmitter levels Source: MGI
    9. response to amphetamine Source: MGI
    10. serotonin metabolic process Source: MGI
    11. signal transduction Source: MGI
    12. visual learning Source: MGI

    Keywords - Molecular functioni

    HydrolaseSAAS annotation

    Keywords - Ligandi

    Metal-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Pde1bImported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97523. Pde1b.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. neuronal cell body Source: Ensembl
    3. nucleus Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9DBS6.
    BgeeiQ9DBS6.
    GenevestigatoriQ9DBS6.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000023132.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9DBS6.
    SMRiQ9DBS6. Positions 37-461.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG056120.
    InParanoidiQ9DBS6.
    KOiK13755.

    Family and domain databases

    Gene3Di1.10.1300.10. 2 hits.
    InterProiIPR003607. HD/PDEase_dom.
    IPR023088. PDEase.
    IPR002073. PDEase_catalytic_dom.
    IPR023174. PDEase_CS.
    IPR013706. PDEase_N.
    [Graphical view]
    PfamiPF00233. PDEase_I. 1 hit.
    PF08499. PDEase_I_N. 1 hit.
    [Graphical view]
    PRINTSiPR00387. PDIESTERASE1.
    SMARTiSM00471. HDc. 1 hit.
    [Graphical view]
    PROSITEiPS00126. PDEASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9DBS6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVKQLENGEV NIEELKKNLE YTASLLEAVY IDETRQILDT EDELRELRSD    50
    AVPSEVRDWL ASTFTQQTRA KGRRAEEKPK FRSIVHAVQA GIFVERMFRR 100
    TYTSVGPTYS TAVHNCLKNL DLWCFDVFSL NRAADDHALR TIVFELLTRH 150
    SLISRFKIPT VFLMSFLEAL ETGYGKYKNP YHNQIHAADV TQTVHCFLLR 200
    TGMVHCLSEI EVLAIIFAAA IHDYEHTGTT NSFHIQTKSE CAILYNDRSV 250
    LENHHISSVF RMMQDDEMNI FINLTKDEFA ELRALVIEMV LATDMSCHFQ 300
    QVKTMKTALQ QLERIDKSKA LSLLLHAADI SHPTKQWSVH SRWTKALMEE 350
    FFRQGDKEAE LGLPFSPLCD RTSTLVAQSQ IGFIDFIVEP TFSVLTDVAE 400
    KSVQPLADDD SKPKSQPSFQ WRQPSLDVDV GDPNPDVVSF RATWTKYIQE 450
    NKQKWKERAA SGITNQMSID ELSPCEEEAP SSPAEDEHNQ NGNLD 495
    Length:495
    Mass (Da):56,598
    Last modified:June 1, 2001 - v1
    Checksum:iFB86B38967CFD0C4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004772 mRNA. Translation: BAB23551.1.
    RefSeqiNP_001272819.1. NM_001285890.1.
    UniGeneiMm.390792.

    Genome annotation databases

    GeneIDi18574.
    KEGGimmu:18574.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004772 mRNA. Translation: BAB23551.1 .
    RefSeqi NP_001272819.1. NM_001285890.1.
    UniGenei Mm.390792.

    3D structure databases

    ProteinModelPortali Q9DBS6.
    SMRi Q9DBS6. Positions 37-461.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000023132.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 18574.
    KEGGi mmu:18574.

    Organism-specific databases

    CTDi 5153.
    MGIi MGI:97523. Pde1b.

    Phylogenomic databases

    HOVERGENi HBG056120.
    InParanoidi Q9DBS6.
    KOi K13755.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9DBS6.
    Bgeei Q9DBS6.
    Genevestigatori Q9DBS6.

    Family and domain databases

    Gene3Di 1.10.1300.10. 2 hits.
    InterProi IPR003607. HD/PDEase_dom.
    IPR023088. PDEase.
    IPR002073. PDEase_catalytic_dom.
    IPR023174. PDEase_CS.
    IPR013706. PDEase_N.
    [Graphical view ]
    Pfami PF00233. PDEase_I. 1 hit.
    PF08499. PDEase_I_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00387. PDIESTERASE1.
    SMARTi SM00471. HDc. 1 hit.
    [Graphical view ]
    PROSITEi PS00126. PDEASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.

    Entry informationi

    Entry nameiQ9DBS6_MOUSE
    AccessioniPrimary (citable) accession number: Q9DBS6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)