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Q9DBS6

- Q9DBS6_MOUSE

UniProt

Q9DBS6 - Q9DBS6_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Pde1b

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 3',5'-cyclic-AMP phosphodiesterase activity Source: Ensembl
  2. calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity Source: MGI
  3. calmodulin-dependent cyclic-nucleotide phosphodiesterase activity Source: MGI
  4. cyclic-nucleotide phosphodiesterase activity Source: MGI
  5. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cAMP catabolic process Source: Ensembl
  2. cellular response to granulocyte macrophage colony-stimulating factor stimulus Source: Ensembl
  3. cellular response to macrophage colony-stimulating factor stimulus Source: Ensembl
  4. cGMP catabolic process Source: Ensembl
  5. locomotory behavior Source: MGI
  6. monocyte differentiation Source: Ensembl
  7. regulation of dopamine metabolic process Source: MGI
  8. regulation of neurotransmitter levels Source: MGI
  9. response to amphetamine Source: MGI
  10. serotonin metabolic process Source: MGI
  11. signal transduction Source: MGI
  12. visual learning Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Keywords - Ligandi

Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Pde1bImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97523. Pde1b.

Subcellular locationi

GO - Cellular componenti

  1. neuronal cell body Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9DBS6.
ExpressionAtlasiQ9DBS6. baseline and differential.
GenevestigatoriQ9DBS6.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023132.

Structurei

3D structure databases

ProteinModelPortaliQ9DBS6.
SMRiQ9DBS6. Positions 37-461.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG056120.
KOiK13755.

Family and domain databases

Gene3Di1.10.1300.10. 2 hits.
InterProiIPR003607. HD/PDEase_dom.
IPR023088. PDEase.
IPR002073. PDEase_catalytic_dom.
IPR023174. PDEase_CS.
IPR013706. PDEase_N.
[Graphical view]
PfamiPF00233. PDEase_I. 1 hit.
PF08499. PDEase_I_N. 1 hit.
[Graphical view]
PRINTSiPR00387. PDIESTERASE1.
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
PROSITEiPS00126. PDEASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DBS6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKQLENGEV NIEELKKNLE YTASLLEAVY IDETRQILDT EDELRELRSD
60 70 80 90 100
AVPSEVRDWL ASTFTQQTRA KGRRAEEKPK FRSIVHAVQA GIFVERMFRR
110 120 130 140 150
TYTSVGPTYS TAVHNCLKNL DLWCFDVFSL NRAADDHALR TIVFELLTRH
160 170 180 190 200
SLISRFKIPT VFLMSFLEAL ETGYGKYKNP YHNQIHAADV TQTVHCFLLR
210 220 230 240 250
TGMVHCLSEI EVLAIIFAAA IHDYEHTGTT NSFHIQTKSE CAILYNDRSV
260 270 280 290 300
LENHHISSVF RMMQDDEMNI FINLTKDEFA ELRALVIEMV LATDMSCHFQ
310 320 330 340 350
QVKTMKTALQ QLERIDKSKA LSLLLHAADI SHPTKQWSVH SRWTKALMEE
360 370 380 390 400
FFRQGDKEAE LGLPFSPLCD RTSTLVAQSQ IGFIDFIVEP TFSVLTDVAE
410 420 430 440 450
KSVQPLADDD SKPKSQPSFQ WRQPSLDVDV GDPNPDVVSF RATWTKYIQE
460 470 480 490
NKQKWKERAA SGITNQMSID ELSPCEEEAP SSPAEDEHNQ NGNLD
Length:495
Mass (Da):56,598
Last modified:June 1, 2001 - v1
Checksum:iFB86B38967CFD0C4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK004772 mRNA. Translation: BAB23551.1.
RefSeqiNP_001272819.1. NM_001285890.1.
UniGeneiMm.390792.

Genome annotation databases

GeneIDi18574.
KEGGimmu:18574.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK004772 mRNA. Translation: BAB23551.1 .
RefSeqi NP_001272819.1. NM_001285890.1.
UniGenei Mm.390792.

3D structure databases

ProteinModelPortali Q9DBS6.
SMRi Q9DBS6. Positions 37-461.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000023132.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 18574.
KEGGi mmu:18574.

Organism-specific databases

CTDi 5153.
MGIi MGI:97523. Pde1b.

Phylogenomic databases

HOVERGENi HBG056120.
KOi K13755.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q9DBS6.
ExpressionAtlasi Q9DBS6. baseline and differential.
Genevestigatori Q9DBS6.

Family and domain databases

Gene3Di 1.10.1300.10. 2 hits.
InterProi IPR003607. HD/PDEase_dom.
IPR023088. PDEase.
IPR002073. PDEase_catalytic_dom.
IPR023174. PDEase_CS.
IPR013706. PDEase_N.
[Graphical view ]
Pfami PF00233. PDEase_I. 1 hit.
PF08499. PDEase_I_N. 1 hit.
[Graphical view ]
PRINTSi PR00387. PDIESTERASE1.
SMARTi SM00471. HDc. 1 hit.
[Graphical view ]
PROSITEi PS00126. PDEASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.

Entry informationi

Entry nameiQ9DBS6_MOUSE
AccessioniPrimary (citable) accession number: Q9DBS6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)