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Q9DB52 (F122A_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein FAM122A
Gene names
Name:Fam122a
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the FAM122 family.

Ontologies

Keywords
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Protein FAM122A
PRO_0000089690

Regions

Compositional bias21 – 288Poly-Gly

Amino acid modifications

Modified residue321Phosphoserine By similarity
Modified residue341Phosphoserine By similarity
Modified residue421Phosphoserine Ref.4
Modified residue451Phosphoserine By similarity
Modified residue591Phosphoserine Ref.6
Modified residue731Phosphoserine Ref.6 Ref.7
Modified residue1401Phosphoserine Ref.4 Ref.5 Ref.6
Modified residue1441Phosphoserine Ref.4 Ref.5 Ref.6
Modified residue1461Phosphothreonine By similarity
Modified residue2671Phosphoserine Ref.3
Modified residue2731Phosphoserine By similarity

Experimental info

Sequence conflict18 – 203PAE → RRR in BAB27811. Ref.1
Sequence conflict371L → P in BAB27811. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9DB52 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: F099612EB932120B

FASTA28430,270
        10         20         30         40         50         60 
MAQEKMELDL ELPAGASPAE GGGPGGGGLR RSNSAPLIHG LSDSSPVFQA EAPSARRNST 

        70         80         90        100        110        120 
TFPSRHGLLL PASPVRMHSS RLHQIKQEEG MDLINRETVH EREVQTAMQI SHSWEESFSL 

       130        140        150        160        170        180 
SDNDVEKSAS PKRIDFIPVS PAPSPTRGIG KQCFSPSLQS FVSSNGLPPS PIPSPTTRFT 

       190        200        210        220        230        240 
TRRSQSPINC IRPSVLGPLK RKCEMETDYQ PKRFFQGITN MLSSDVAQLS DPGVCVSSDT 

       250        260        270        280 
LDGNSSSAGS SCNSPAKVST TTDSPVSPAQ AASPFIPVDE LSSK

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
Tissue: Cecum, Cerebellum, Embryo and Spleen.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye and Mammary gland.
[3]"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.
Mol. Cell. Proteomics 3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-267, MASS SPECTROMETRY.
Tissue: Embryonic brain.
[4]"Large-scale phosphorylation analysis of mouse liver."
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42; SER-140 AND SER-144, MASS SPECTROMETRY.
Tissue: Liver.
[5]"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140 AND SER-144, MASS SPECTROMETRY.
Tissue: Liver.
[6]"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry."
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M.
J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-59; SER-73; SER-140 AND SER-144, MASS SPECTROMETRY.
Tissue: Melanoma.
[7]"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-73, MASS SPECTROMETRY.
Tissue: Embryonic fibroblast.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK005219 mRNA. Translation: BAB23889.1.
AK011741 mRNA. Translation: BAB27811.1.
AK033646 mRNA. Translation: BAC28405.1.
AK077654 mRNA. Translation: BAC36930.1.
AK172089 mRNA. Translation: BAE42820.1.
BC028637 mRNA. Translation: AAH28637.1.
BC083062 mRNA. Translation: AAH83062.1.
IPIIPI00154109.
RefSeqNP_080796.1. NM_026520.3.
UniGeneMm.440181.

3D structure databases

ProteinModelPortalQ9DB52.
ModBaseSearch...

PTM databases

PhosphoSiteQ9DB52.

Proteomic databases

PaxDbQ9DB52.
PRIDEQ9DB52.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000099556; ENSMUSP00000097152; ENSMUSG00000074922.
GeneID68034.
KEGGmmu:68034.
UCSCuc008haq.1. mouse.

Organism-specific databases

CTD116224.
MGIMGI:1915284. Fam122a.

Phylogenomic databases

eggNOGNOG83987.
GeneTreeENSGT00390000015476.
HOGENOMHOG000294073.
HOVERGENHBG073694.
InParanoidQ9DB52.
OMASTTFPNR.
OrthoDBEOG4BK552.

Gene expression databases

BgeeQ9DB52.
GenevestigatorQ9DB52.
GermOnlineENSMUSG00000074922. Mus musculus.

Family and domain databases

InterProIPR026716. FAM122.
[Graphical view]
PANTHERPTHR22227. PTHR22227. 1 hit.
ProtoNetSearch...

Other

NextBio326258.
SOURCESearch...

Entry information

Entry nameF122A_MOUSE
AccessionPrimary (citable) accession number: Q9DB52
Secondary accession number(s): Q3TA50, Q9D078
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: June 1, 2001
Last modified: April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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