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Q9DAV2

- Q9DAV2_MOUSE

UniProt

Q9DAV2 - Q9DAV2_MOUSE

Protein
Submitted name:

Vascular endothelial growth factor receptor 1

Gene

Flt1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. identical protein binding Source: MGI
    3. vascular endothelial growth factor-activated receptor activity Source: MGI

    GO - Biological processi

    1. angiogenesis Source: MGI
    2. cell migration Source: MGI
    3. patterning of blood vessels Source: MGI
    4. sprouting angiogenesis Source: MGI
    5. vascular endothelial growth factor receptor signaling pathway Source: MGI
    6. vascular endothelial growth factor signaling pathway Source: GOC

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Vascular endothelial growth factor receptor 1Imported
    Gene namesi
    Name:Flt1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:95558. Flt1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: InterPro
    2. receptor complex Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ9DAV2.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00720000108679.
    HOGENOMiHOG000114763.
    HOVERGENiHBG053003.

    Family and domain databases

    Gene3Di2.60.40.10. 5 hits.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    IPR009135. VEGFR1_rcpt.
    [Graphical view]
    PANTHERiPTHR24416:SF126. PTHR24416:SF126. 1 hit.
    PfamiPF07679. I-set. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view]
    PRINTSiPR01833. VEGFRECEPTR1.
    SMARTiSM00409. IG. 4 hits.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9DAV2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSCWDTAVL PYALLGCLLL TGYGSGSKLK VPELSLKGTQ HVMQAGQTLF    50
    LKCRGEAAHS WSLPTTVSQE DKRLSITPPS ACGRDNRQFC STLTLDTAQA 100
    NHTGLYTCRY LPTSTSKKKK AESSIYIFVS DAGSPFIEMH TDIPKLVHMT 150
    EGRQLIIPCR VTSPNVTVTL KKFPFDTLTP DGQRITWDSR RGFIIANATY 200
    KEIGLLNCEA TVNGHLYQTN YLTHRQTNTI LDVQIRPPSP VRLLHGQTLV 250
    LNCTATTELN TRVQMSWNYP GKATKRASIR QRIDRSHSHN NVFHSVLKIN 300
    NVESRDKGLY TCRVKSGSSF QSFNTSVHVY EKGFISVKHR KQPVQETTAG 350
    RRSYRLSMKV KAFPSPEIVW LKDGSPATLK SARYLVHGYS LIIKDVTTED 400
    AGDYTILLGI KQSRLFKNLT ATLIVNVKPQ IYEKSVSSLP SPPLYPLGSR 450
    QVLTCTVYGI PRPTITWLWH PCHHNHSKER YDFCTENEES FILDPSSNLG 500
    NRIESISQRM TVIEGTNKPG ELILLGNQAG CTLLAPYPNY TFNLLSALQS 550
    HLWGGTWSPH KCWD 564
    Length:564
    Mass (Da):63,247
    Last modified:June 1, 2001 - v1
    Checksum:iAA102CEF71B677DC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122299 Genomic DNA. No translation available.
    AC131730 Genomic DNA. No translation available.
    AK005502 mRNA. Translation: BAB24084.1.
    UniGeneiMm.389712.

    Genome annotation databases

    EnsembliENSMUST00000031652; ENSMUSP00000031652; ENSMUSG00000029648.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122299 Genomic DNA. No translation available.
    AC131730 Genomic DNA. No translation available.
    AK005502 mRNA. Translation: BAB24084.1 .
    UniGenei Mm.389712.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000031652 ; ENSMUSP00000031652 ; ENSMUSG00000029648 .

    Organism-specific databases

    MGIi MGI:95558. Flt1.

    Phylogenomic databases

    GeneTreei ENSGT00720000108679.
    HOGENOMi HOG000114763.
    HOVERGENi HBG053003.

    Miscellaneous databases

    ChiTaRSi FLT1. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9DAV2.

    Family and domain databases

    Gene3Di 2.60.40.10. 5 hits.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    IPR009135. VEGFR1_rcpt.
    [Graphical view ]
    PANTHERi PTHR24416:SF126. PTHR24416:SF126. 1 hit.
    Pfami PF07679. I-set. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view ]
    PRINTSi PR01833. VEGFRECEPTR1.
    SMARTi SM00409. IG. 4 hits.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    10. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ9DAV2_MOUSE
    AccessioniPrimary (citable) accession number: Q9DAV2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3