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Q9DAV2

- Q9DAV2_MOUSE

UniProt

Q9DAV2 - Q9DAV2_MOUSE

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Protein
Submitted name:

Vascular endothelial growth factor receptor 1

Gene

Flt1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. identical protein binding Source: MGI
  3. vascular endothelial growth factor-activated receptor activity Source: MGI

GO - Biological processi

  1. angiogenesis Source: MGI
  2. cell migration Source: MGI
  3. patterning of blood vessels Source: MGI
  4. positive regulation of hematopoietic progenitor cell differentiation Source: MGI
  5. response to hypoxia Source: MGI
  6. sprouting angiogenesis Source: MGI
  7. vascular endothelial growth factor receptor signaling pathway Source: MGI
  8. vascular endothelial growth factor signaling pathway Source: GOC
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Vascular endothelial growth factor receptor 1Imported
Gene namesi
Name:Flt1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:95558. Flt1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: InterPro
  2. receptor complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9DAV2.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118923.
HOGENOMiHOG000114763.
HOVERGENiHBG053003.

Family and domain databases

Gene3Di2.60.40.10. 5 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR009135. VEGFR1_rcpt.
[Graphical view]
PANTHERiPTHR24416:SF126. PTHR24416:SF126. 1 hit.
PfamiPF07679. I-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSiPR01833. VEGFRECEPTR1.
SMARTiSM00409. IG. 4 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9DAV2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSCWDTAVL PYALLGCLLL TGYGSGSKLK VPELSLKGTQ HVMQAGQTLF
60 70 80 90 100
LKCRGEAAHS WSLPTTVSQE DKRLSITPPS ACGRDNRQFC STLTLDTAQA
110 120 130 140 150
NHTGLYTCRY LPTSTSKKKK AESSIYIFVS DAGSPFIEMH TDIPKLVHMT
160 170 180 190 200
EGRQLIIPCR VTSPNVTVTL KKFPFDTLTP DGQRITWDSR RGFIIANATY
210 220 230 240 250
KEIGLLNCEA TVNGHLYQTN YLTHRQTNTI LDVQIRPPSP VRLLHGQTLV
260 270 280 290 300
LNCTATTELN TRVQMSWNYP GKATKRASIR QRIDRSHSHN NVFHSVLKIN
310 320 330 340 350
NVESRDKGLY TCRVKSGSSF QSFNTSVHVY EKGFISVKHR KQPVQETTAG
360 370 380 390 400
RRSYRLSMKV KAFPSPEIVW LKDGSPATLK SARYLVHGYS LIIKDVTTED
410 420 430 440 450
AGDYTILLGI KQSRLFKNLT ATLIVNVKPQ IYEKSVSSLP SPPLYPLGSR
460 470 480 490 500
QVLTCTVYGI PRPTITWLWH PCHHNHSKER YDFCTENEES FILDPSSNLG
510 520 530 540 550
NRIESISQRM TVIEGTNKPG ELILLGNQAG CTLLAPYPNY TFNLLSALQS
560
HLWGGTWSPH KCWD
Length:564
Mass (Da):63,247
Last modified:June 1, 2001 - v1
Checksum:iAA102CEF71B677DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122299 Genomic DNA. No translation available.
AC131730 Genomic DNA. No translation available.
AK005502 mRNA. Translation: BAB24084.1.
UniGeneiMm.389712.

Genome annotation databases

EnsembliENSMUST00000031652; ENSMUSP00000031652; ENSMUSG00000029648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122299 Genomic DNA. No translation available.
AC131730 Genomic DNA. No translation available.
AK005502 mRNA. Translation: BAB24084.1 .
UniGenei Mm.389712.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000031652 ; ENSMUSP00000031652 ; ENSMUSG00000029648 .

Organism-specific databases

MGIi MGI:95558. Flt1.

Phylogenomic databases

GeneTreei ENSGT00760000118923.
HOGENOMi HOG000114763.
HOVERGENi HBG053003.

Miscellaneous databases

ChiTaRSi Flt1. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9DAV2.

Family and domain databases

Gene3Di 2.60.40.10. 5 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR009135. VEGFR1_rcpt.
[Graphical view ]
PANTHERi PTHR24416:SF126. PTHR24416:SF126. 1 hit.
Pfami PF07679. I-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view ]
PRINTSi PR01833. VEGFRECEPTR1.
SMARTi SM00409. IG. 4 hits.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9DAV2_MOUSE
AccessioniPrimary (citable) accession number: Q9DAV2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 26, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3