Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein delta homolog 1

Gene

Dlk1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Protein delta homolog 1Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Dlk1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:94900. Dlk1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei214 – 235HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500934821824 – 290Sequence analysisAdd BLAST267

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi45 ↔ 54PROSITE-ProRule annotation
Disulfide bondi76 ↔ 85PROSITE-ProRule annotation
Disulfide bondi115 ↔ 124PROSITE-ProRule annotation
Disulfide bondi158 ↔ 167PROSITE-ProRule annotation
Disulfide bondi198 ↔ 207PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000040856.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063104.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 55EGF-likeInterPro annotationAdd BLAST34
Domaini59 – 86EGF-likeInterPro annotationAdd BLAST28
Domaini88 – 125EGF-likeInterPro annotationAdd BLAST38
Domaini127 – 168EGF-likeInterPro annotationAdd BLAST42
Domaini172 – 208EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
GeneTreeiENSGT00840000129708.
HOGENOMiHOG000072581.
HOVERGENiHBG007065.

Family and domain databases

InterProiView protein in InterPro
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
PfamiView protein in Pfam
PF00008. EGF. 3 hits.
SMARTiView protein in SMART
SM00181. EGF. 5 hits.
SM00179. EGF_CA. 3 hits.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 4 hits.
PS01186. EGF_2. 5 hits.
PS50026. EGF_3. 5 hits.

Sequencei

Sequence statusi: Complete.

Q9DAU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIATGALLRV LLLLLAFGHS TYGAECDPPC DPQYGFCEAD NVCRCHVGWE
60 70 80 90 100
GPLCDKCVTA PGCVNGVCKE PWQCICKDGW DGKFCEIDVR ACTSTPCANN
110 120 130 140 150
GTCVDLEKGQ YECSCTPGFS GKDCQHKAGP CVINGSPCQH GGACVDDEGQ
160 170 180 190 200
ASHASCLCPP GFSGNFCEIV AATNSCTPNP CENDGVCTDI GGDFRCRCPA
210 220 230 240 250
GFVDKTCSRP AICFTILGVL TSLVVLGTVA IVFLNKCETW VSNLRYNHML
260 270 280 290
RKKKNLLLQY NSGEELAVNI IFPEKIDMTT FNKEAGDEEI
Length:290
Mass (Da):31,117
Last modified:June 1, 2001 - v1
Checksum:iEED42925D5AA267E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC165954 Genomic DNA. No translation available.
AK005522 mRNA. Translation: BAB24096.1.
RefSeqiNP_001177632.1. NM_001190703.1.
UniGeneiMm.157069.

Genome annotation databases

EnsembliENSMUST00000109843; ENSMUSP00000105469; ENSMUSG00000040856.
GeneIDi13386.
UCSCiuc007pan.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC165954 Genomic DNA. No translation available.
AK005522 mRNA. Translation: BAB24096.1.
RefSeqiNP_001177632.1. NM_001190703.1.
UniGeneiMm.157069.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063104.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000109843; ENSMUSP00000105469; ENSMUSG00000040856.
GeneIDi13386.
UCSCiuc007pan.2. mouse.

Organism-specific databases

CTDi8788.
MGIiMGI:94900. Dlk1.

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
GeneTreeiENSGT00840000129708.
HOGENOMiHOG000072581.
HOVERGENiHBG007065.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040856.

Family and domain databases

InterProiView protein in InterPro
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
PfamiView protein in Pfam
PF00008. EGF. 3 hits.
SMARTiView protein in SMART
SM00181. EGF. 5 hits.
SM00179. EGF_CA. 3 hits.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 4 hits.
PS01186. EGF_2. 5 hits.
PS50026. EGF_3. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9DAU5_MOUSE
AccessioniPrimary (citable) accession number: Q9DAU5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 15, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.