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Protein

Fatty acid-binding protein 12

Gene

Fabp12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in lipid transport.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei107 – 1071Fatty acidBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Enzyme and pathway databases

ReactomeiR-MMU-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein 12
Gene namesi
Name:Fabp12
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1922747. Fabp12.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Fatty acid-binding protein 12PRO_0000342882Add
BLAST

Proteomic databases

PaxDbiQ9DAK4.
PRIDEiQ9DAK4.

PTM databases

PhosphoSiteiQ9DAK4.

Expressioni

Tissue specificityi

Highly expressed in adult retina and testis.1 Publication

Gene expression databases

BgeeiENSMUSG00000027530.
GenevisibleiQ9DAK4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029043.

Structurei

3D structure databases

ProteinModelPortaliQ9DAK4.
SMRiQ9DAK4. Positions 1-132.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni127 – 1293Fatty acid bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
HOVERGENiHBG005633.
InParanoidiQ9DAK4.
OMAiDNDAMIH.
OrthoDBiEOG091G0QSV.
PhylomeDBiQ9DAK4.
TreeFamiTF316894.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR031261. FABP12.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF76. PTHR11955:SF76. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9DAK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDQLQGTWK SVSCDNFENY MKELGVGRAS RKLGCLAKPT VTISTDGDLI
60 70 80 90 100
TIKTKSIFKN KEISFKLGEE FEETTPSGRK SKSTVILDND SLVQVQDWDG
110 120 130
KEATICRRLV DGKMVVESAV NNVTCTRTYQ RV
Length:132
Mass (Da):14,758
Last modified:June 1, 2001 - v1
Checksum:i7A20C53780845F61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU733649 mRNA. Translation: ACI03639.1.
AK005765 mRNA. Translation: BAB24227.1.
CH466577 Genomic DNA. Translation: EDL05167.1.
CH466577 Genomic DNA. Translation: EDL05168.1.
BC030910 mRNA. Translation: AAH30910.1.
CCDSiCCDS17239.1.
RefSeqiNP_083586.1. NM_029310.1.
XP_006530156.1. XM_006530093.2.
XP_006530157.1. XM_006530094.2.
XP_006530158.1. XM_006530095.2.
XP_006530159.1. XM_006530096.2.
XP_006530160.1. XM_006530097.2.
XP_006530162.1. XM_006530099.2.
XP_011246451.1. XM_011248149.1.
UniGeneiMm.47052.

Genome annotation databases

EnsembliENSMUST00000029043; ENSMUSP00000029043; ENSMUSG00000027530.
ENSMUST00000117917; ENSMUSP00000112464; ENSMUSG00000027530.
ENSMUST00000119761; ENSMUSP00000112958; ENSMUSG00000027530.
ENSMUST00000172126; ENSMUSP00000131101; ENSMUSG00000027530.
GeneIDi75497.
KEGGimmu:75497.
UCSCiuc008opm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU733649 mRNA. Translation: ACI03639.1.
AK005765 mRNA. Translation: BAB24227.1.
CH466577 Genomic DNA. Translation: EDL05167.1.
CH466577 Genomic DNA. Translation: EDL05168.1.
BC030910 mRNA. Translation: AAH30910.1.
CCDSiCCDS17239.1.
RefSeqiNP_083586.1. NM_029310.1.
XP_006530156.1. XM_006530093.2.
XP_006530157.1. XM_006530094.2.
XP_006530158.1. XM_006530095.2.
XP_006530159.1. XM_006530096.2.
XP_006530160.1. XM_006530097.2.
XP_006530162.1. XM_006530099.2.
XP_011246451.1. XM_011248149.1.
UniGeneiMm.47052.

3D structure databases

ProteinModelPortaliQ9DAK4.
SMRiQ9DAK4. Positions 1-132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029043.

PTM databases

PhosphoSiteiQ9DAK4.

Proteomic databases

PaxDbiQ9DAK4.
PRIDEiQ9DAK4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000029043; ENSMUSP00000029043; ENSMUSG00000027530.
ENSMUST00000117917; ENSMUSP00000112464; ENSMUSG00000027530.
ENSMUST00000119761; ENSMUSP00000112958; ENSMUSG00000027530.
ENSMUST00000172126; ENSMUSP00000131101; ENSMUSG00000027530.
GeneIDi75497.
KEGGimmu:75497.
UCSCiuc008opm.1. mouse.

Organism-specific databases

CTDi646486.
MGIiMGI:1922747. Fabp12.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
HOVERGENiHBG005633.
InParanoidiQ9DAK4.
OMAiDNDAMIH.
OrthoDBiEOG091G0QSV.
PhylomeDBiQ9DAK4.
TreeFamiTF316894.

Enzyme and pathway databases

ReactomeiR-MMU-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Miscellaneous databases

PROiQ9DAK4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027530.
GenevisibleiQ9DAK4. MM.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR031261. FABP12.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF76. PTHR11955:SF76. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFBP12_MOUSE
AccessioniPrimary (citable) accession number: Q9DAK4
Secondary accession number(s): B7SUM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.