##gff-version 3 Q9DA32 UniProtKB Chain 1 373 . . . ID=PRO_0000218920;Note=SUN domain-containing protein 5 Q9DA32 UniProtKB Topological domain 1 103 . . . Note=Nuclear;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9DA32 UniProtKB Transmembrane 104 120 . . . Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9DA32 UniProtKB Topological domain 121 373 . . . Note=Perinuclear space;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9DA32 UniProtKB Domain 204 362 . . . Note=SUN;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00802 Q9DA32 UniProtKB Coiled coil 136 180 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9DA32 UniProtKB Alternative sequence 44 69 . . . ID=VSP_046528;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15552040,ECO:0000303|PubMed:16141072;Dbxref=PMID:15552040,PMID:16141072 Q9DA32 UniProtKB Mutagenesis 112 112 . . . Note=Corresponds to R-114 variant associated with SPGF16 in human. Impairs nuclear inner membrane location%2C expressed in the cytosol with some protein aggregation near the nuclear envelope. G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Mutagenesis 160 160 . . . Note=Corresponds to variant K-162 associated with SPGF16 in human. Increases interaction with DNAJB13. Impairs nuclear inner membrane location%2C expressed in the cytosol with some protein aggregation near the nuclear envelope. M->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Mutagenesis 259 259 . . . Note=Corresponds to M-261 variant associated with SPGF16 in human. Decreases protein solubility%2C impairs nuclear inner membrane location and decreases interaction with DNAJB13. V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Mutagenesis 273 273 . . . Note=Corresponds to M-275 variant associated with SPGF16 in human. Impairs nuclear inner membrane location and decreases interaction with DNAJB13. T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Mutagenesis 346 346 . . . Note=Corresponds to I-348 variant associated with SPGF16 in human. Impairs nuclear inner membrane location and increases interaction with DNAJB13. N->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Mutagenesis 354 354 . . . Note=Corresponds to C-356 variant associated with SPGF16 in human. Impairs nuclear inner membrane location and decreases interaction with DNAJB13. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29298896;Dbxref=PMID:29298896 Q9DA32 UniProtKB Sequence conflict 287 287 . . . Note=P->L;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9DA32 UniProtKB Sequence conflict 294 294 . . . Note=I->F;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9DA32 UniProtKB Sequence conflict 319 322 . . . Note=VIQM->IIQT;Ontology_term=ECO:0000305;evidence=ECO:0000305