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Protein

Probable rRNA-processing protein EBP2

Gene

Ebna1bp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the processing of the 27S pre-rRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Probable rRNA-processing protein EBP2
Gene namesi
Name:Ebna1bp2
Synonyms:Ebp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1916322. Ebna1bp2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Probable rRNA-processing protein EBP2PRO_0000119994Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei3 – 31PhosphothreonineBy similarity
Modified residuei7 – 71PhosphoserineBy similarity
Modified residuei9 – 91PhosphoserineBy similarity
Modified residuei11 – 111PhosphoserineBy similarity
Modified residuei13 – 131PhosphoserineBy similarity
Modified residuei264 – 2641PhosphoserineBy similarity
Modified residuei270 – 2701PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9D903.
MaxQBiQ9D903.
PaxDbiQ9D903.
PeptideAtlasiQ9D903.
PRIDEiQ9D903.

PTM databases

iPTMnetiQ9D903.
PhosphoSiteiQ9D903.

Miscellaneous databases

PMAP-CutDBQ9D903.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028729.
CleanExiMM_EBNA1BP2.
ExpressionAtlasiQ9D903. baseline and differential.
GenevisibleiQ9D903. MM.

Interactioni

Subunit structurei

Interacts with WDR46.By similarity

Protein-protein interaction databases

BioGridi213211. 1 interaction.
DIPiDIP-48579N.
IntActiQ9D903. 1 interaction.
MINTiMINT-4093941.
STRINGi10090.ENSMUSP00000030501.

Structurei

3D structure databases

ProteinModelPortaliQ9D903.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili135 – 17137Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the EBP2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3080. Eukaryota.
ENOG410YYHN. LUCA.
GeneTreeiENSGT00390000014984.
HOGENOMiHOG000231281.
HOVERGENiHBG031528.
InParanoidiQ9D903.
KOiK14823.
OMAiKKYQKGM.
OrthoDBiEOG091G0HC5.
PhylomeDBiQ9D903.
TreeFamiTF314642.

Family and domain databases

InterProiIPR008610. Ebp2.
[Graphical view]
PANTHERiPTHR13028. PTHR13028. 1 hit.
PfamiPF05890. Ebp2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D903-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTPPLSESD SESDACLASD QELQDAFSRG LLKPGLNVVL EKPKKAVNDV
60 70 80 90 100
SGLKQCLAEF RRDLEWVERL DVTLGPVPEV SETQPTPQNQ DQKKGVNPED
110 120 130 140 150
DFQREMSFYR QAQAAVLAVL PRLHQLQVPT KRPTDYFAEM AKSDQQMQKI
160 170 180 190 200
RQKLQTKQAA MEKSEKAKQL RALRKYGKKV QTEVLQKRQR EKAHMMNAIK
210 220 230 240 250
KYQKGFSDKL DFLEGDQKPV ERSAKAGGKG QQMSKGPNAK RRYKNQKFGF
260 270 280 290 300
GGKKKGSKWN TKESYDDVSS FRAKVAHGKG SRRPGKKGAN KRPGKRARQK

LKSKAR
Length:306
Mass (Da):34,703
Last modified:June 1, 2001 - v1
Checksum:iC612FB25A47084EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007491 mRNA. Translation: BAB25065.1.
AK134732 mRNA. Translation: BAE22261.1.
AK167070 mRNA. Translation: BAE39230.1.
AK168269 mRNA. Translation: BAE40215.1.
AL669952 Genomic DNA. Translation: CAM15603.1.
BC054723 mRNA. Translation: AAH54723.1.
BC062876 mRNA. Translation: AAH62876.1.
CCDSiCCDS18555.1.
RefSeqiNP_081208.1. NM_026932.4.
UniGeneiMm.29906.

Genome annotation databases

EnsembliENSMUST00000030501; ENSMUSP00000030501; ENSMUSG00000028729.
GeneIDi69072.
KEGGimmu:69072.
UCSCiuc008ukn.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007491 mRNA. Translation: BAB25065.1.
AK134732 mRNA. Translation: BAE22261.1.
AK167070 mRNA. Translation: BAE39230.1.
AK168269 mRNA. Translation: BAE40215.1.
AL669952 Genomic DNA. Translation: CAM15603.1.
BC054723 mRNA. Translation: AAH54723.1.
BC062876 mRNA. Translation: AAH62876.1.
CCDSiCCDS18555.1.
RefSeqiNP_081208.1. NM_026932.4.
UniGeneiMm.29906.

3D structure databases

ProteinModelPortaliQ9D903.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi213211. 1 interaction.
DIPiDIP-48579N.
IntActiQ9D903. 1 interaction.
MINTiMINT-4093941.
STRINGi10090.ENSMUSP00000030501.

PTM databases

iPTMnetiQ9D903.
PhosphoSiteiQ9D903.

Proteomic databases

EPDiQ9D903.
MaxQBiQ9D903.
PaxDbiQ9D903.
PeptideAtlasiQ9D903.
PRIDEiQ9D903.

Protocols and materials databases

DNASUi69072.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030501; ENSMUSP00000030501; ENSMUSG00000028729.
GeneIDi69072.
KEGGimmu:69072.
UCSCiuc008ukn.2. mouse.

Organism-specific databases

CTDi10969.
MGIiMGI:1916322. Ebna1bp2.

Phylogenomic databases

eggNOGiKOG3080. Eukaryota.
ENOG410YYHN. LUCA.
GeneTreeiENSGT00390000014984.
HOGENOMiHOG000231281.
HOVERGENiHBG031528.
InParanoidiQ9D903.
KOiK14823.
OMAiKKYQKGM.
OrthoDBiEOG091G0HC5.
PhylomeDBiQ9D903.
TreeFamiTF314642.

Miscellaneous databases

PMAP-CutDBQ9D903.
PROiQ9D903.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028729.
CleanExiMM_EBNA1BP2.
ExpressionAtlasiQ9D903. baseline and differential.
GenevisibleiQ9D903. MM.

Family and domain databases

InterProiIPR008610. Ebp2.
[Graphical view]
PANTHERiPTHR13028. PTHR13028. 1 hit.
PfamiPF05890. Ebp2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEBP2_MOUSE
AccessioniPrimary (citable) accession number: Q9D903
Secondary accession number(s): A2ACZ0, Q3TKB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.