Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable rRNA-processing protein EBP2

Gene

Ebna1bp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the processing of the 27S pre-rRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis

Enzyme and pathway databases

ReactomeiR-MMU-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable rRNA-processing protein EBP2
Gene namesi
Name:Ebna1bp2
Synonyms:Ebp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1916322. Ebna1bp2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001199941 – 306Probable rRNA-processing protein EBP2Add BLAST306

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei3PhosphothreonineBy similarity1
Modified residuei7PhosphoserineBy similarity1
Modified residuei9PhosphoserineBy similarity1
Modified residuei11PhosphoserineBy similarity1
Modified residuei13PhosphoserineBy similarity1
Cross-linki93Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki179Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki218Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei264PhosphoserineBy similarity1
Modified residuei270PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9D903.
MaxQBiQ9D903.
PaxDbiQ9D903.
PeptideAtlasiQ9D903.
PRIDEiQ9D903.

PTM databases

iPTMnetiQ9D903.
PhosphoSitePlusiQ9D903.

Miscellaneous databases

PMAP-CutDBiQ9D903.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028729.
CleanExiMM_EBNA1BP2.
ExpressionAtlasiQ9D903. baseline and differential.
GenevisibleiQ9D903. MM.

Interactioni

Subunit structurei

Interacts with WDR46.By similarity

Protein-protein interaction databases

BioGridi213211. 1 interactor.
CORUMiQ9D903.
DIPiDIP-48579N.
IntActiQ9D903. 1 interactor.
MINTiMINT-4093941.
STRINGi10090.ENSMUSP00000030501.

Structurei

3D structure databases

ProteinModelPortaliQ9D903.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili135 – 171Sequence analysisAdd BLAST37

Sequence similaritiesi

Belongs to the EBP2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3080. Eukaryota.
ENOG410YYHN. LUCA.
GeneTreeiENSGT00390000014984.
HOGENOMiHOG000231281.
HOVERGENiHBG031528.
InParanoidiQ9D903.
KOiK14823.
OMAiMFHRQAQ.
OrthoDBiEOG091G0HC5.
PhylomeDBiQ9D903.
TreeFamiTF314642.

Family and domain databases

InterProiView protein in InterPro
IPR008610. Ebp2.
PANTHERiPTHR13028. PTHR13028. 1 hit.
PfamiView protein in Pfam
PF05890. Ebp2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9D903-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTPPLSESD SESDACLASD QELQDAFSRG LLKPGLNVVL EKPKKAVNDV
60 70 80 90 100
SGLKQCLAEF RRDLEWVERL DVTLGPVPEV SETQPTPQNQ DQKKGVNPED
110 120 130 140 150
DFQREMSFYR QAQAAVLAVL PRLHQLQVPT KRPTDYFAEM AKSDQQMQKI
160 170 180 190 200
RQKLQTKQAA MEKSEKAKQL RALRKYGKKV QTEVLQKRQR EKAHMMNAIK
210 220 230 240 250
KYQKGFSDKL DFLEGDQKPV ERSAKAGGKG QQMSKGPNAK RRYKNQKFGF
260 270 280 290 300
GGKKKGSKWN TKESYDDVSS FRAKVAHGKG SRRPGKKGAN KRPGKRARQK

LKSKAR
Length:306
Mass (Da):34,703
Last modified:June 1, 2001 - v1
Checksum:iC612FB25A47084EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007491 mRNA. Translation: BAB25065.1.
AK134732 mRNA. Translation: BAE22261.1.
AK167070 mRNA. Translation: BAE39230.1.
AK168269 mRNA. Translation: BAE40215.1.
AL669952 Genomic DNA. Translation: CAM15603.1.
BC054723 mRNA. Translation: AAH54723.1.
BC062876 mRNA. Translation: AAH62876.1.
CCDSiCCDS18555.1.
RefSeqiNP_081208.1. NM_026932.4.
UniGeneiMm.29906.

Genome annotation databases

EnsembliENSMUST00000030501; ENSMUSP00000030501; ENSMUSG00000028729.
GeneIDi69072.
KEGGimmu:69072.
UCSCiuc008ukn.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiEBP2_MOUSE
AccessioniPrimary (citable) accession number: Q9D903
Secondary accession number(s): A2ACZ0, Q3TKB5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 1, 2001
Last modified: September 27, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families