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Protein

BolA-like protein 1

Gene

Bola1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
BolA-like protein 1
Gene namesi
Name:Bola1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1916418 Bola1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002012341 – 137BolA-like protein 1Add BLAST137

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei81PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9D8S9
MaxQBiQ9D8S9
PaxDbiQ9D8S9
PeptideAtlasiQ9D8S9
PRIDEiQ9D8S9

PTM databases

iPTMnetiQ9D8S9
PhosphoSitePlusiQ9D8S9

Expressioni

Gene expression databases

BgeeiENSMUSG00000015943
CleanExiMM_BOLA1
GenevisibleiQ9D8S9 MM

Interactioni

Subunit structurei

Interacts with GLRX5.By similarity

Protein-protein interaction databases

IntActiQ9D8S9, 3 interactors
MINTiQ9D8S9
STRINGi10090.ENSMUSP00000016087

Structurei

Secondary structure

1137
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi27 – 29Combined sources3
Helixi31 – 43Combined sources13
Beta strandi47 – 53Combined sources7
Beta strandi57 – 59Combined sources3
Beta strandi66 – 73Combined sources8
Helixi75 – 77Combined sources3
Helixi82 – 92Combined sources11
Helixi94 – 97Combined sources4
Turni98 – 100Combined sources3
Beta strandi102 – 109Combined sources8
Turni111 – 116Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V60NMR-A13-128[»]
ProteinModelPortaliQ9D8S9
SMRiQ9D8S9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9D8S9

Family & Domainsi

Sequence similaritiesi

Belongs to the BolA/IbaG family.Curated

Phylogenomic databases

eggNOGiKOG2313 Eukaryota
COG0271 LUCA
GeneTreeiENSGT00510000048165
HOGENOMiHOG000255169
HOVERGENiHBG080902
InParanoidiQ9D8S9
KOiK22066
OMAiSKKTRGT
OrthoDBiEOG091G14DH
PhylomeDBiQ9D8S9
TreeFamiTF354266

Family and domain databases

InterProiView protein in InterPro
IPR002634 BolA
IPR036065 BolA-like_sf
PANTHERiPTHR12735 PTHR12735, 1 hit
PfamiView protein in Pfam
PF01722 BolA, 1 hit
PIRSFiPIRSF003113 BolA, 1 hit
SUPFAMiSSF82657 SSF82657, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D8S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSARSAQCM VSMATRSCVS RGSAGSAAAG PVEAAIRAKL EQALSPEVLE
60 70 80 90 100
LRNESGGHAV PAGSETHFRV AVVSSRFEGM SPLQRHRLVH EALSEELAGP
110 120 130
VHALAIQAKT PAQWRENPQL DISPPCLGGS KKTRGTS
Length:137
Mass (Da):14,379
Last modified:June 1, 2001 - v1
Checksum:iEC5B187A3C597155
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007718 mRNA Translation: BAB25210.1
BC027558 mRNA Translation: AAH27558.1
CCDSiCCDS17632.1
RefSeqiNP_081251.1, NM_026975.2
XP_006502075.1, XM_006502012.1
UniGeneiMm.104531

Genome annotation databases

EnsembliENSMUST00000016087; ENSMUSP00000016087; ENSMUSG00000015943
ENSMUST00000107099; ENSMUSP00000102716; ENSMUSG00000015943
ENSMUST00000177442; ENSMUSP00000134765; ENSMUSG00000015943
GeneIDi69168
KEGGimmu:69168
UCSCiuc008qmg.2 mouse

Entry informationi

Entry nameiBOLA1_MOUSE
AccessioniPrimary (citable) accession number: Q9D8S9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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