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Q9D8C4

- IN35_MOUSE

UniProt

Q9D8C4 - IN35_MOUSE

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Protein

Interferon-induced 35 kDa protein homolog

Gene
Ifi35
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Interferon-induced 35 kDa protein homolog
Short name:
IFP 35
Short name:
Ifi-35
Gene namesi
Name:Ifi35
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1917360. Ifi35.

Subcellular locationi

Nucleus By similarity
Note: Nuclear following IFN treatment By similarity.

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 286285Interferon-induced 35 kDa protein homologPRO_0000159705Add
BLAST

Proteomic databases

MaxQBiQ9D8C4.
PaxDbiQ9D8C4.
PRIDEiQ9D8C4.

PTM databases

PhosphoSiteiQ9D8C4.

Expressioni

Inductioni

By interferon gamma By similarity.

Gene expression databases

ArrayExpressiQ9D8C4.
BgeeiQ9D8C4.
CleanExiMM_IFI35.
GenevestigatoriQ9D8C4.

Interactioni

Subunit structurei

Homodimer. Also interacts with B-ATF By similarity.

Protein-protein interaction databases

BioGridi213868. 1 interaction.
IntActiQ9D8C4. 2 interactions.
MINTiMINT-1848756.

Structurei

3D structure databases

ProteinModelPortaliQ9D8C4.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni5 – 2622Leucine-zipperAdd
BLAST

Sequence similaritiesi

Belongs to the NMI family.

Phylogenomic databases

eggNOGiNOG28883.
GeneTreeiENSGT00530000063686.
HOGENOMiHOG000230968.
HOVERGENiHBG052125.
InParanoidiQ9D8C4.
OMAiLVFRGHT.
OrthoDBiEOG7SR4N0.
PhylomeDBiQ9D8C4.
TreeFamiTF332752.

Family and domain databases

InterProiIPR009909. Nmi/IFP35_dom.
IPR009938. Nmi/IFP35_N.
[Graphical view]
PfamiPF07334. IFP_35_N. 1 hit.
PF07292. NID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D8C4-1 [UniParc]FASTAAdd to Basket

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MSVTLQTVLY SLQEEQARLK MRLQELQQLK RERTGSPGAK IPFSVPEVPL    50
VFQGQTKQGR QVPKFVVSNL KVCCPLPEGS ALVTFEDPKV VDRLLQQKEH 100
RVNLEDCRLR VQVQPLELPV VTNIQVSSQP DNHRVLVSGF PAGLRLSEEE 150
LLDKLEIFFG KAKNGGGDVE TREMLQGTVM LGFADEEVAQ HLCQIGQFRV 200
PLDRQQVLLR VSPYVSGEIQ KAEIKFQQAP HSVLVTNIPD VMDAQELHDI 250
LEIHFQKPTR GGGEVEALTV VPSGQQGLAI FTSESS 286
Length:286
Mass (Da):31,876
Last modified:January 23, 2007 - v3
Checksum:i51EB0BAAD7054454
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti108 – 1081R → W in AAH08158. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008161 mRNA. Translation: BAB25503.1.
AK131884 mRNA. Translation: BAE20851.1.
BC008158 mRNA. Translation: AAH08158.1.
CCDSiCCDS25471.1.
RefSeqiNP_081596.1. NM_027320.4.
UniGeneiMm.45558.

Genome annotation databases

EnsembliENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358.
GeneIDi70110.
KEGGimmu:70110.
UCSCiuc007lox.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008161 mRNA. Translation: BAB25503.1 .
AK131884 mRNA. Translation: BAE20851.1 .
BC008158 mRNA. Translation: AAH08158.1 .
CCDSi CCDS25471.1.
RefSeqi NP_081596.1. NM_027320.4.
UniGenei Mm.45558.

3D structure databases

ProteinModelPortali Q9D8C4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 213868. 1 interaction.
IntActi Q9D8C4. 2 interactions.
MINTi MINT-1848756.

PTM databases

PhosphoSitei Q9D8C4.

Proteomic databases

MaxQBi Q9D8C4.
PaxDbi Q9D8C4.
PRIDEi Q9D8C4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000010502 ; ENSMUSP00000010502 ; ENSMUSG00000010358 .
GeneIDi 70110.
KEGGi mmu:70110.
UCSCi uc007lox.1. mouse.

Organism-specific databases

CTDi 3430.
MGIi MGI:1917360. Ifi35.

Phylogenomic databases

eggNOGi NOG28883.
GeneTreei ENSGT00530000063686.
HOGENOMi HOG000230968.
HOVERGENi HBG052125.
InParanoidi Q9D8C4.
OMAi LVFRGHT.
OrthoDBi EOG7SR4N0.
PhylomeDBi Q9D8C4.
TreeFami TF332752.

Miscellaneous databases

NextBioi 331016.
PROi Q9D8C4.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9D8C4.
Bgeei Q9D8C4.
CleanExi MM_IFI35.
Genevestigatori Q9D8C4.

Family and domain databases

InterProi IPR009909. Nmi/IFP35_dom.
IPR009938. Nmi/IFP35_N.
[Graphical view ]
Pfami PF07334. IFP_35_N. 1 hit.
PF07292. NID. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Small intestine and Stomach.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Mammary tumor.

Entry informationi

Entry nameiIN35_MOUSE
AccessioniPrimary (citable) accession number: Q9D8C4
Secondary accession number(s): Q3V2E7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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