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Protein

Interferon-induced 35 kDa protein homolog

Gene

Ifi35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Interferon-induced 35 kDa protein homolog
Short name:
IFP 35
Short name:
Ifi-35
Gene namesi
Name:Ifi35
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1917360. Ifi35.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001597051 – 286Interferon-induced 35 kDa protein homologAdd BLAST286

Proteomic databases

EPDiQ9D8C4.
MaxQBiQ9D8C4.
PaxDbiQ9D8C4.
PeptideAtlasiQ9D8C4.
PRIDEiQ9D8C4.

PTM databases

iPTMnetiQ9D8C4.
PhosphoSitePlusiQ9D8C4.

Expressioni

Inductioni

By interferon gamma.By similarity

Gene expression databases

BgeeiENSMUSG00000010358.
CleanExiMM_IFI35.
ExpressionAtlasiQ9D8C4. baseline and differential.
GenevisibleiQ9D8C4. MM.

Interactioni

Subunit structurei

Homodimer. Also interacts with B-ATF (By similarity).By similarity

Protein-protein interaction databases

BioGridi213868. 1 interactor.
IntActiQ9D8C4. 4 interactors.
MINTiMINT-1848756.
STRINGi10090.ENSMUSP00000010502.

Structurei

3D structure databases

ProteinModelPortaliQ9D8C4.
SMRiQ9D8C4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni5 – 26Leucine-zipperAdd BLAST22

Sequence similaritiesi

Belongs to the NMI family.Curated

Phylogenomic databases

eggNOGiENOG410IZG7. Eukaryota.
ENOG4111RNW. LUCA.
GeneTreeiENSGT00530000063686.
HOGENOMiHOG000230968.
HOVERGENiHBG052125.
InParanoidiQ9D8C4.
OMAiHFQKPTR.
OrthoDBiEOG091G0CE6.
PhylomeDBiQ9D8C4.
TreeFamiTF332752.

Family and domain databases

InterProiView protein in InterPro
IPR034460. IFP35.
IPR009909. Nmi/IFP35_dom.
IPR009938. Nmi/IFP35_N.
PANTHERiPTHR15225:SF9. PTHR15225:SF9. 1 hit.
PfamiView protein in Pfam
PF07334. IFP_35_N. 1 hit.
PF07292. NID. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9D8C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTLQTVLY SLQEEQARLK MRLQELQQLK RERTGSPGAK IPFSVPEVPL
60 70 80 90 100
VFQGQTKQGR QVPKFVVSNL KVCCPLPEGS ALVTFEDPKV VDRLLQQKEH
110 120 130 140 150
RVNLEDCRLR VQVQPLELPV VTNIQVSSQP DNHRVLVSGF PAGLRLSEEE
160 170 180 190 200
LLDKLEIFFG KAKNGGGDVE TREMLQGTVM LGFADEEVAQ HLCQIGQFRV
210 220 230 240 250
PLDRQQVLLR VSPYVSGEIQ KAEIKFQQAP HSVLVTNIPD VMDAQELHDI
260 270 280
LEIHFQKPTR GGGEVEALTV VPSGQQGLAI FTSESS
Length:286
Mass (Da):31,876
Last modified:January 23, 2007 - v3
Checksum:i51EB0BAAD7054454
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108R → W in AAH08158 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008161 mRNA. Translation: BAB25503.1.
AK131884 mRNA. Translation: BAE20851.1.
BC008158 mRNA. Translation: AAH08158.1.
CCDSiCCDS25471.1.
RefSeqiNP_081596.1. NM_027320.4.
UniGeneiMm.45558.

Genome annotation databases

EnsembliENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358.
GeneIDi70110.
KEGGimmu:70110.
UCSCiuc007lox.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiIN35_MOUSE
AccessioniPrimary (citable) accession number: Q9D8C4
Secondary accession number(s): Q3V2E7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 107 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families