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Q9D8C4 (IN35_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Interferon-induced 35 kDa protein homolog

Short name=IFP 35
Short name=Ifi-35
Gene names
Name:Ifi35
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Homodimer. Also interacts with B-ATF By similarity.

Subcellular location

Nucleus By similarity. Note: Nuclear following IFN treatment By similarity.

Induction

By interferon gamma By similarity.

Sequence similarities

Belongs to the NMI family.

Ontologies

Keywords
   Cellular componentNucleus
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 286285Interferon-induced 35 kDa protein homolog
PRO_0000159705

Regions

Region5 – 2622Leucine-zipper

Experimental info

Sequence conflict1081R → W in AAH08158. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9D8C4 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 51EB0BAAD7054454

FASTA28631,876
        10         20         30         40         50         60 
MSVTLQTVLY SLQEEQARLK MRLQELQQLK RERTGSPGAK IPFSVPEVPL VFQGQTKQGR 

        70         80         90        100        110        120 
QVPKFVVSNL KVCCPLPEGS ALVTFEDPKV VDRLLQQKEH RVNLEDCRLR VQVQPLELPV 

       130        140        150        160        170        180 
VTNIQVSSQP DNHRVLVSGF PAGLRLSEEE LLDKLEIFFG KAKNGGGDVE TREMLQGTVM 

       190        200        210        220        230        240 
LGFADEEVAQ HLCQIGQFRV PLDRQQVLLR VSPYVSGEIQ KAEIKFQQAP HSVLVTNIPD 

       250        260        270        280 
VMDAQELHDI LEIHFQKPTR GGGEVEALTV VPSGQQGLAI FTSESS 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Small intestine and Stomach.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Mammary tumor.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK008161 mRNA. Translation: BAB25503.1.
AK131884 mRNA. Translation: BAE20851.1.
BC008158 mRNA. Translation: AAH08158.1.
CCDSCCDS25471.1.
RefSeqNP_081596.1. NM_027320.4.
UniGeneMm.45558.

3D structure databases

ProteinModelPortalQ9D8C4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid213868. 1 interaction.
IntActQ9D8C4. 2 interactions.
MINTMINT-1848756.

PTM databases

PhosphoSiteQ9D8C4.

Proteomic databases

MaxQBQ9D8C4.
PaxDbQ9D8C4.
PRIDEQ9D8C4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358.
GeneID70110.
KEGGmmu:70110.
UCSCuc007lox.1. mouse.

Organism-specific databases

CTD3430.
MGIMGI:1917360. Ifi35.

Phylogenomic databases

eggNOGNOG28883.
GeneTreeENSGT00530000063686.
HOGENOMHOG000230968.
HOVERGENHBG052125.
InParanoidQ9D8C4.
OMALVFRGHT.
OrthoDBEOG7SR4N0.
PhylomeDBQ9D8C4.
TreeFamTF332752.

Gene expression databases

ArrayExpressQ9D8C4.
BgeeQ9D8C4.
CleanExMM_IFI35.
GenevestigatorQ9D8C4.

Family and domain databases

InterProIPR009909. Nmi/IFP35_dom.
IPR009938. Nmi/IFP35_N.
[Graphical view]
PfamPF07334. IFP_35_N. 1 hit.
PF07292. NID. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio331016.
PROQ9D8C4.
SOURCESearch...

Entry information

Entry nameIN35_MOUSE
AccessionPrimary (citable) accession number: Q9D8C4
Secondary accession number(s): Q3V2E7
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot