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Q9D8C4

- IN35_MOUSE

UniProt

Q9D8C4 - IN35_MOUSE

Protein

Interferon-induced 35 kDa protein homolog

Gene

Ifi35

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Interferon-induced 35 kDa protein homolog
    Short name:
    IFP 35
    Short name:
    Ifi-35
    Gene namesi
    Name:Ifi35
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1917360. Ifi35.

    Subcellular locationi

    Nucleus By similarity
    Note: Nuclear following IFN treatment.By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 286285Interferon-induced 35 kDa protein homologPRO_0000159705Add
    BLAST

    Proteomic databases

    MaxQBiQ9D8C4.
    PaxDbiQ9D8C4.
    PRIDEiQ9D8C4.

    PTM databases

    PhosphoSiteiQ9D8C4.

    Expressioni

    Inductioni

    By interferon gamma.By similarity

    Gene expression databases

    ArrayExpressiQ9D8C4.
    BgeeiQ9D8C4.
    CleanExiMM_IFI35.
    GenevestigatoriQ9D8C4.

    Interactioni

    Subunit structurei

    Homodimer. Also interacts with B-ATF By similarity.By similarity

    Protein-protein interaction databases

    BioGridi213868. 1 interaction.
    IntActiQ9D8C4. 2 interactions.
    MINTiMINT-1848756.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9D8C4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni5 – 2622Leucine-zipperAdd
    BLAST

    Sequence similaritiesi

    Belongs to the NMI family.Curated

    Phylogenomic databases

    eggNOGiNOG28883.
    GeneTreeiENSGT00530000063686.
    HOGENOMiHOG000230968.
    HOVERGENiHBG052125.
    InParanoidiQ9D8C4.
    OMAiLVFRGHT.
    OrthoDBiEOG7SR4N0.
    PhylomeDBiQ9D8C4.
    TreeFamiTF332752.

    Family and domain databases

    InterProiIPR009909. Nmi/IFP35_dom.
    IPR009938. Nmi/IFP35_N.
    [Graphical view]
    PfamiPF07334. IFP_35_N. 1 hit.
    PF07292. NID. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9D8C4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVTLQTVLY SLQEEQARLK MRLQELQQLK RERTGSPGAK IPFSVPEVPL    50
    VFQGQTKQGR QVPKFVVSNL KVCCPLPEGS ALVTFEDPKV VDRLLQQKEH 100
    RVNLEDCRLR VQVQPLELPV VTNIQVSSQP DNHRVLVSGF PAGLRLSEEE 150
    LLDKLEIFFG KAKNGGGDVE TREMLQGTVM LGFADEEVAQ HLCQIGQFRV 200
    PLDRQQVLLR VSPYVSGEIQ KAEIKFQQAP HSVLVTNIPD VMDAQELHDI 250
    LEIHFQKPTR GGGEVEALTV VPSGQQGLAI FTSESS 286
    Length:286
    Mass (Da):31,876
    Last modified:January 23, 2007 - v3
    Checksum:i51EB0BAAD7054454
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti108 – 1081R → W in AAH08158. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK008161 mRNA. Translation: BAB25503.1.
    AK131884 mRNA. Translation: BAE20851.1.
    BC008158 mRNA. Translation: AAH08158.1.
    CCDSiCCDS25471.1.
    RefSeqiNP_081596.1. NM_027320.4.
    UniGeneiMm.45558.

    Genome annotation databases

    EnsembliENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358.
    GeneIDi70110.
    KEGGimmu:70110.
    UCSCiuc007lox.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK008161 mRNA. Translation: BAB25503.1 .
    AK131884 mRNA. Translation: BAE20851.1 .
    BC008158 mRNA. Translation: AAH08158.1 .
    CCDSi CCDS25471.1.
    RefSeqi NP_081596.1. NM_027320.4.
    UniGenei Mm.45558.

    3D structure databases

    ProteinModelPortali Q9D8C4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 213868. 1 interaction.
    IntActi Q9D8C4. 2 interactions.
    MINTi MINT-1848756.

    PTM databases

    PhosphoSitei Q9D8C4.

    Proteomic databases

    MaxQBi Q9D8C4.
    PaxDbi Q9D8C4.
    PRIDEi Q9D8C4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000010502 ; ENSMUSP00000010502 ; ENSMUSG00000010358 .
    GeneIDi 70110.
    KEGGi mmu:70110.
    UCSCi uc007lox.1. mouse.

    Organism-specific databases

    CTDi 3430.
    MGIi MGI:1917360. Ifi35.

    Phylogenomic databases

    eggNOGi NOG28883.
    GeneTreei ENSGT00530000063686.
    HOGENOMi HOG000230968.
    HOVERGENi HBG052125.
    InParanoidi Q9D8C4.
    OMAi LVFRGHT.
    OrthoDBi EOG7SR4N0.
    PhylomeDBi Q9D8C4.
    TreeFami TF332752.

    Miscellaneous databases

    NextBioi 331016.
    PROi Q9D8C4.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9D8C4.
    Bgeei Q9D8C4.
    CleanExi MM_IFI35.
    Genevestigatori Q9D8C4.

    Family and domain databases

    InterProi IPR009909. Nmi/IFP35_dom.
    IPR009938. Nmi/IFP35_N.
    [Graphical view ]
    Pfami PF07334. IFP_35_N. 1 hit.
    PF07292. NID. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Small intestine and Stomach.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Mammary tumor.

    Entry informationi

    Entry nameiIN35_MOUSE
    AccessioniPrimary (citable) accession number: Q9D8C4
    Secondary accession number(s): Q3V2E7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 14, 2001
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 86 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3