Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Carcinoembryonic antigen-related cell adhesion molecule 18

Gene

Ceacam18

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Carcinoembryonic antigen-related cell adhesion molecule 18
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1919681. Ceacam18.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini31 – 330300ExtracellularSequence analysisAdd
BLAST
Transmembranei331 – 35121HelicalSequence analysisAdd
BLAST
Topological domaini352 – 37625CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence analysisAdd
BLAST
Chaini31 – 376346Carcinoembryonic antigen-related cell adhesion molecule 18PRO_0000339379Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi69 – 691N-linked (GlcNAc...)Sequence analysis
Glycosylationi95 – 951N-linked (GlcNAc...)Sequence analysis
Glycosylationi110 – 1101N-linked (GlcNAc...)Sequence analysis
Disulfide bondi257 ↔ 298PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9D871.
PRIDEiQ9D871.

Expressioni

Tissue specificityi

Mostly expressed in the small and large intestine and at lower levels also in other organs.1 Publication

Gene expression databases

BgeeiENSMUSG00000030472.
GenevisibleiQ9D871. MM.

Structurei

3D structure databases

ProteinModelPortaliQ9D871.
SMRiQ9D871. Positions 43-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini229 – 31486Ig-like C2-typeAdd
BLAST

Sequence similaritiesi

Belongs to the immunoglobulin superfamily. CEA family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JB7I. Eukaryota.
ENOG4111BYI. LUCA.
GeneTreeiENSGT00760000119187.
HOGENOMiHOG000111529.
HOVERGENiHBG107644.
InParanoidiQ9D871.
KOiK06499.
OMAiSQVEMEC.
OrthoDBiEOG091G0AAA.
PhylomeDBiQ9D871.
TreeFamiTF336859.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 3 hits.
SM00408. IGc2. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D871-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSRPSFSP WRWLTLVASL LTCGICQASG QIFISPDSLL GVEKYRTILT
60 70 80 90 100
LENVPEDVLE YSWYRGKDNS TENMIFSYKP PNTRHPGPSY SGRENVTRAG
110 120 130 140 150
SLVVRMSAVN DTGYYTVEVD TSNETQRATG WLQIVKLRSN PGISANTSAL
160 170 180 190 200
VEGMDSVVAK CLTNSSNISW YVNFVPTSGS NRMTISPDGK TLIIHRVSRY
210 220 230 240 250
DHTLQCAIED VPEILQKSEL IQLTVAYGPD YVSLWTQPYF FAGVLTADIG
260 270 280 290 300
SSVQLECNCF SKPEPRYHWI HNGSFLSIPE NNMTLPSLSW EQMGSYRCVV
310 320 330 340 350
ENPETQLTFY RDVTIQPPRP PLPTVNRELY IPGPLVIFLI LLTSLGGAFV
360 370
CRVLVYSLFQ SCSRGKTCHK CPWQTN
Length:376
Mass (Da):42,215
Last modified:June 1, 2001 - v1
Checksum:i9E095E8BA179DCF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008389 mRNA. Translation: BAB25642.1.
BC042780 mRNA. Translation: AAH42780.1.
CCDSiCCDS21177.1.
RefSeqiNP_082512.1. NM_028236.1.
UniGeneiMm.158821.

Genome annotation databases

EnsembliENSMUST00000032663; ENSMUSP00000032663; ENSMUSG00000030472.
GeneIDi72431.
KEGGimmu:72431.
UCSCiuc009gnf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008389 mRNA. Translation: BAB25642.1.
BC042780 mRNA. Translation: AAH42780.1.
CCDSiCCDS21177.1.
RefSeqiNP_082512.1. NM_028236.1.
UniGeneiMm.158821.

3D structure databases

ProteinModelPortaliQ9D871.
SMRiQ9D871. Positions 43-316.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI43.001.

Proteomic databases

PaxDbiQ9D871.
PRIDEiQ9D871.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032663; ENSMUSP00000032663; ENSMUSG00000030472.
GeneIDi72431.
KEGGimmu:72431.
UCSCiuc009gnf.1. mouse.

Organism-specific databases

CTDi729767.
MGIiMGI:1919681. Ceacam18.

Phylogenomic databases

eggNOGiENOG410JB7I. Eukaryota.
ENOG4111BYI. LUCA.
GeneTreeiENSGT00760000119187.
HOGENOMiHOG000111529.
HOVERGENiHBG107644.
InParanoidiQ9D871.
KOiK06499.
OMAiSQVEMEC.
OrthoDBiEOG091G0AAA.
PhylomeDBiQ9D871.
TreeFamiTF336859.

Miscellaneous databases

PROiQ9D871.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030472.
GenevisibleiQ9D871. MM.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 3 hits.
SM00408. IGc2. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCEA18_MOUSE
AccessioniPrimary (citable) accession number: Q9D871
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.