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Protein

Actin-related protein 6

Gene

Actr6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 6
Short name:
mArp6
Gene namesi
Name:Actr6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1914269. Actr6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000891062 – 396Actin-related protein 6Add BLAST395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylthreonineBy similarity1
Modified residuei260N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9D864.
MaxQBiQ9D864.
PaxDbiQ9D864.
PeptideAtlasiQ9D864.
PRIDEiQ9D864.

PTM databases

iPTMnetiQ9D864.
PhosphoSitePlusiQ9D864.

Expressioni

Gene expression databases

CleanExiMM_ACTR6.

Interactioni

Subunit structurei

Interacts with CBX1, CBX3 and CBX5.By similarity

Protein-protein interaction databases

IntActiQ9D864. 1 interactor.
STRINGi10090.ENSMUSP00000020109.

Structurei

3D structure databases

ProteinModelPortaliQ9D864.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family. ARP6 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0680. Eukaryota.
ENOG410XPT5. LUCA.
HOGENOMiHOG000170496.
HOVERGENiHBG097980.
InParanoidiQ9D864.
KOiK11662.
PhylomeDBiQ9D864.
TreeFamiTF105780.

Family and domain databases

InterProiView protein in InterPro
IPR004000. Actin.
IPR030054. Arp6.
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF47. PTHR11937:SF47. 1 hit.
PfamiView protein in Pfam
PF00022. Actin. 1 hit.
SMARTiView protein in SMART
SM00268. ACTIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D864-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTLVLDNGA YNAKIGYSHD SVSVIPNCQF RSKTARLKTF TANQIDEIKD
60 70 80 90 100
PSGLFYILPF QKGYLVNWDV QRQVWDYLFG KEMYQVDFLD TNIIITEPYF
110 120 130 140 150
NFTSIQESMN EILFEEYQFQ AVLRVNAGAL SAHRYFRDNP SELCCIIVDS
160 170 180 190 200
GYSFTHIVPY CRSKKKKEAI IRINVGGKLL TNHLKEIISY RQLHVMDETH
210 220 230 240 250
VINQVKEDVC YVSQDFYRDM DIAKLKGEDN TVMIDYVLPD FSTIKKGFCK
260 270 280 290 300
PREEMVLSGK YKSGEQILRL ANERFAVPEI LFNPSDIGIQ EMGIPEAIVY
310 320 330 340 350
SIQNLPEEMQ PHFFKNIVLT GGNSLFPGFR ERVYSEVRCL TPTDYDVSVV
360 370 380 390
LPENPITYSW EGGKLISEND DFEDMVVTRE DYEENGHSVC EEKFDI
Length:396
Mass (Da):45,785
Last modified:May 10, 2004 - v2
Checksum:i550B68A2CBEAC82C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti26P → T in BAC40429 (PubMed:16141072).Curated1
Sequence conflicti263S → F in BAB25654 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008409 mRNA. Translation: BAB25654.1.
AK088571 mRNA. Translation: BAC40429.1.
BC062137 mRNA. Translation: AAH62137.1.
CCDSiCCDS24118.1.
RefSeqiNP_080190.1. NM_025914.2.
UniGeneiMm.335292.

Genome annotation databases

GeneIDi67019.
KEGGimmu:67019.
UCSCiuc007gss.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiARP6_MOUSE
AccessioniPrimary (citable) accession number: Q9D864
Secondary accession number(s): Q8BTV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: May 10, 2004
Last modified: October 25, 2017
This is version 106 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families