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Unreviewed, UniProtKB/TrEMBL Q9D859 (Q9D859_MOUSE)

Last modified January 19, 2010. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesSubmitted name:
    Putative uncharacterized protein EMBL BAB25667.1
Gene names
Name: Rac1 MGI 97845
OrganismMus musculus (Mouse) EMBL BAB25667.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMus

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the small GTPase superfamily. Rho family.

Ontologies

Keywords
   Cellular componentMembrane Spearmint SPM003578
   LigandGTP-binding RuleBase RU003312V0 Spearmint SPM003578
Nucleotide-binding
Gene Ontology (GO)
   Biological processaxon guidance

Inferred from mutant phenotype. Source: MGI

cell adhesion

Inferred from direct assay. Source: MGI

cerebral cortex radially oriented cell migration

Inferred from mutant phenotype. Source: MGI

cytoskeleton organization

Inferred from direct assay. Source: MGI

dendrite development

Inferred from direct assay. Source: MGI

embryonic olfactory bulb interneuron precursor migration

Inferred from mutant phenotype. Source: MGI

endocytosis

Inferred from direct assay. Source: MGI

hyperosmotic response

Inferred from direct assay. Source: MGI

lamellipodium assembly

Inferred from direct assay. Source: MGI

positive regulation of actin filament polymerization

Inferred from direct assay. Source: MGI

positive regulation of phosphoinositide 3-kinase activity

Inferred from mutant phenotype. Source: MGI

regulation of cell migration

Inferred from mutant phenotype. Source: MGI

small GTPase mediated signal transduction

Inferred from direct assay. Source: MGI

   Cellular componentcytoplasmic membrane-bounded vesicle

Inferred from direct assay. Source: MGI

extrinsic to plasma membrane

Inferred from direct assay. Source: MGI

lamellipodium

Inferred from direct assay. Source: MGI

membrane fraction

Inferred from direct assay. Source: MGI

   Molecular functionGTP binding

Inferred from direct assay. Source: MGI

GTPase activity

Inferred from direct assay. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9D859-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 59EC483A45E45A67

FASTA19221,464
        10         20         30         40         50         60 
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG 

        70         80         90        100        110        120 
QEDYERLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPNTPI ILVGTKLDLR 

       130        140        150        160        170        180 
DDKDTIEKLK EKKLTPITYP QGLAMAKEIG AVKYLECSAL TQRGLKTVFD EAIRAVLCPP 

       190 
PVKKRKRKCL LL 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAB25667.1.
Tissue: Small intestine EMBL BAB25667.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK008435 mRNA. Translation: BAB25667.1.
IPIIPI00761613.
UniGeneMm.292510
Mm.475073

3D structure databases

HSSPHSSP built from PDB template 1DS6 based on UniProtKB P15153.
SMRQ9D859. Positions 1-192.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9D859.

Genome annotation databases

EnsemblENSMUST00000080537; ENSMUSP00000079380; ENSMUSG00000001847; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:97845. Rac1.

Phylogenomic databases

HOVERGENQ9D859.

Gene expression databases

ArrayExpressQ9D859.
BgeeQ9D859.
GenevestigatorQ9D859.

Family and domain databases

InterProIPR003578. GTPase_Rho.
IPR013753. Ras.
IPR001806. Ras_GTPase.
IPR005225. Small_GTP_bd.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SMARTSM00174. RHO. 1 hit.
[Graphical view]
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51420. RHO. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

Entry information

Entry nameQ9D859_MOUSE
AccessionPrimary (citable) accession number: Q9D859
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: January 19, 2010
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information