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Q9D859

- Q9D859_MOUSE

UniProt

Q9D859 - Q9D859_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Rac1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. GTPase activity Source: MGI
  2. GTP binding Source: MGI

GO - Biological processi

  1. actin filament polymerization Source: MGI
  2. anatomical structure arrangement Source: MGI
  3. auditory receptor cell morphogenesis Source: MGI
  4. axon guidance Source: MGI
  5. cell adhesion Source: MGI
  6. cell-cell junction organization Source: MGI
  7. cell migration Source: MGI
  8. cerebral cortex radially oriented cell migration Source: MGI
  9. cochlea morphogenesis Source: MGI
  10. cytoskeleton organization Source: MGI
  11. dendrite development Source: MGI
  12. dendrite morphogenesis Source: MGI
  13. dopaminergic neuron differentiation Source: MGI
  14. embryonic olfactory bulb interneuron precursor migration Source: MGI
  15. endocytosis Source: MGI
  16. epithelial cell morphogenesis Source: MGI
  17. G-protein coupled receptor signaling pathway Source: MGI
  18. GTP catabolic process Source: GOC
  19. hyperosmotic response Source: MGI
  20. lamellipodium assembly Source: MGI
  21. positive regulation of actin filament polymerization Source: MGI
  22. positive regulation of lamellipodium assembly Source: MGI
  23. positive regulation of phosphatidylinositol 3-kinase activity Source: MGI
  24. protein localization to plasma membrane Source: MGI
  25. regulation of cell migration Source: MGI
  26. ruffle organization Source: MGI
  27. small GTPase mediated signal transduction Source: MGI
  28. substrate adhesion-dependent cell spreading Source: MGI
  29. Wnt signaling pathway, planar cell polarity pathway Source: MGI
Complete GO annotation...

Keywords - Ligandi

GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Rac1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97845. Rac1.

Subcellular locationi

GO - Cellular componenti

  1. cell projection Source: MGI
  2. cytoplasm Source: MGI
  3. cytoplasmic membrane-bounded vesicle Source: MGI
  4. extrinsic component of plasma membrane Source: MGI
  5. lamellipodium Source: MGI
  6. membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

MembraneSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ9D859.

Expressioni

Gene expression databases

GenevestigatoriQ9D859.

Interactioni

Protein-protein interaction databases

MINTiMINT-1517323.
STRINGi10090.ENSMUSP00000098058.

Structurei

3D structure databases

ProteinModelPortaliQ9D859.
SMRiQ9D859. Positions 1-192.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG009351.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00174. RHO. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51420. RHO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D859 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP
60 70 80 90 100
VNLGLWDTAG QEDYERLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE
110 120 130 140 150
VRHHCPNTPI ILVGTKLDLR DDKDTIEKLK EKKLTPITYP QGLAMAKEIG
160 170 180 190
AVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKRKRKCL LL
Length:192
Mass (Da):21,464
Last modified:June 1, 2001 - v1
Checksum:i59EC483A45E45A67
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008435 mRNA. Translation: BAB25667.1.
UniGeneiMm.292510.
Mm.469963.
Mm.475073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008435 mRNA. Translation: BAB25667.1 .
UniGenei Mm.292510.
Mm.469963.
Mm.475073.

3D structure databases

ProteinModelPortali Q9D859.
SMRi Q9D859. Positions 1-192.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1517323.
STRINGi 10090.ENSMUSP00000098058.

Proteomic databases

PRIDEi Q9D859.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97845. Rac1.

Phylogenomic databases

HOVERGENi HBG009351.

Miscellaneous databases

ChiTaRSi RAC1. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9D859.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
[Graphical view ]
Pfami PF00071. Ras. 1 hit.
[Graphical view ]
PRINTSi PR00449. RASTRNSFRMNG.
SMARTi SM00174. RHO. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00231. small_GTP. 1 hit.
PROSITEi PS51420. RHO. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Small intestineImported.

Entry informationi

Entry nameiQ9D859_MOUSE
AccessioniPrimary (citable) accession number: Q9D859
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)