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Q9D859

- Q9D859_MOUSE

UniProt

Q9D859 - Q9D859_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Rac1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTPase activity Source: MGI
    2. GTP binding Source: MGI
    3. protein binding Source: MGI

    GO - Biological processi

    1. actin filament polymerization Source: MGI
    2. anatomical structure arrangement Source: MGI
    3. auditory receptor cell morphogenesis Source: MGI
    4. axon guidance Source: MGI
    5. cell adhesion Source: MGI
    6. cell-cell junction organization Source: MGI
    7. cell migration Source: MGI
    8. cerebral cortex radially oriented cell migration Source: MGI
    9. cochlea morphogenesis Source: MGI
    10. cytoskeleton organization Source: MGI
    11. dendrite development Source: MGI
    12. dendrite morphogenesis Source: MGI
    13. dopaminergic neuron differentiation Source: MGI
    14. embryonic olfactory bulb interneuron precursor migration Source: MGI
    15. endocytosis Source: MGI
    16. epithelial cell morphogenesis Source: MGI
    17. G-protein coupled receptor signaling pathway Source: MGI
    18. GTP catabolic process Source: GOC
    19. hyperosmotic response Source: MGI
    20. lamellipodium assembly Source: MGI
    21. positive regulation of actin filament polymerization Source: MGI
    22. positive regulation of lamellipodium assembly Source: MGI
    23. positive regulation of phosphatidylinositol 3-kinase activity Source: MGI
    24. protein localization to plasma membrane Source: MGI
    25. regulation of cell migration Source: MGI
    26. ruffle organization Source: MGI
    27. small GTPase mediated signal transduction Source: MGI
    28. substrate adhesion-dependent cell spreading Source: MGI
    29. Wnt signaling pathway, planar cell polarity pathway Source: MGI

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Rac1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97845. Rac1.

    Subcellular locationi

    GO - Cellular componenti

    1. cell projection Source: MGI
    2. cytoplasm Source: MGI
    3. cytoplasmic membrane-bounded vesicle Source: MGI
    4. extrinsic component of plasma membrane Source: MGI
    5. lamellipodium Source: MGI
    6. membrane Source: MGI

    Keywords - Cellular componenti

    MembraneSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9D859.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9D859.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1517323.
    STRINGi10090.ENSMUSP00000098058.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9D859.
    SMRiQ9D859. Positions 1-192.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the small GTPase superfamily. Rho family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG009351.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003578. Small_GTPase_Rho.
    [Graphical view]
    PfamiPF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SMARTiSM00174. RHO. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.
    PROSITEiPS51420. RHO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9D859-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP    50
    VNLGLWDTAG QEDYERLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE 100
    VRHHCPNTPI ILVGTKLDLR DDKDTIEKLK EKKLTPITYP QGLAMAKEIG 150
    AVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKRKRKCL LL 192
    Length:192
    Mass (Da):21,464
    Last modified:June 1, 2001 - v1
    Checksum:i59EC483A45E45A67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK008435 mRNA. Translation: BAB25667.1.
    UniGeneiMm.292510.
    Mm.469963.
    Mm.475073.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK008435 mRNA. Translation: BAB25667.1 .
    UniGenei Mm.292510.
    Mm.469963.
    Mm.475073.

    3D structure databases

    ProteinModelPortali Q9D859.
    SMRi Q9D859. Positions 1-192.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1517323.
    STRINGi 10090.ENSMUSP00000098058.

    Proteomic databases

    PRIDEi Q9D859.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:97845. Rac1.

    Phylogenomic databases

    HOVERGENi HBG009351.

    Miscellaneous databases

    ChiTaRSi RAC1. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9D859.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003578. Small_GTPase_Rho.
    [Graphical view ]
    Pfami PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SMARTi SM00174. RHO. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51420. RHO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Small intestineImported.

    Entry informationi

    Entry nameiQ9D859_MOUSE
    AccessioniPrimary (citable) accession number: Q9D859
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)