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Protein

Cytochrome b-c1 complex subunit 7

Gene

Uqcrb

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This component is involved in redox-linked proton pumping (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b-c1 complex subunit 7
Alternative name(s):
Complex III subunit 7
Complex III subunit VII
Ubiquinol-cytochrome c reductase complex 14 kDa protein
Gene namesi
Name:Uqcrb
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1914780 Uqcrb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001935252 – 111Cytochrome b-c1 complex subunit 7Add BLAST110

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei12N6-acetyllysine; alternateCombined sources1
Modified residuei12N6-succinyllysine; alternateCombined sources1
Modified residuei19N6-acetyllysineCombined sources1
Modified residuei78N6-acetyllysine; alternateCombined sources1
Modified residuei78N6-succinyllysine; alternateCombined sources1
Modified residuei83N6-acetyllysineCombined sources1
Modified residuei88N6-acetyllysine; alternateCombined sources1
Modified residuei88N6-succinyllysine; alternateCombined sources1
Modified residuei96N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9D855
MaxQBiQ9D855
PaxDbiQ9D855
PRIDEiQ9D855
TopDownProteomicsiQ9D855

PTM databases

iPTMnetiQ9D855
PhosphoSitePlusiQ9D855

Expressioni

Gene expression databases

CleanExiMM_UQCRB

Interactioni

Subunit structurei

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).By similarity

Protein-protein interaction databases

CORUMiQ9D855
IntActiQ9D855, 2 interactors
STRINGi10090.ENSMUSP00000021993

Structurei

3D structure databases

ProteinModelPortaliQ9D855
SMRiQ9D855
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UQCRB/QCR7 family.Curated

Phylogenomic databases

eggNOGiKOG3440 Eukaryota
ENOG4111V1G LUCA
HOGENOMiHOG000188221
HOVERGENiHBG002984
InParanoidiQ9D855
PhylomeDBiQ9D855

Family and domain databases

Gene3Di1.10.1090.10, 1 hit
InterProiView protein in InterPro
IPR003197 QCR7
IPR036544 QCR7_sf
PANTHERiPTHR12022 PTHR12022, 1 hit
PfamiView protein in Pfam
PF02271 UCR_14kD, 1 hit
PIRSFiPIRSF000022 Bc1_14K, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD008153 Cyt_bd_ubiquinol_oxidase_14kDa, 1 hit
SUPFAMiSSF81524 SSF81524, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D855-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGRSAVSAS SKWLDGFRKW YYNAAGFNKL GLMRDDTLHE TEDVKEAIRR
60 70 80 90 100
LPEDLYNDRM LRIKRALDLT MRHQILPKDQ WTKYEEDKFY LEPYLKEVIR
110
ERKEREEWAK K
Length:111
Mass (Da):13,527
Last modified:January 23, 2007 - v3
Checksum:iA4C9BEFA39CBE94A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7V → F in AAH31607 (PubMed:15489334).Curated1
Sequence conflicti61L → F in AAH31607 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008455 mRNA Translation: BAB25678.1
BC031607 mRNA Translation: AAH31607.1
CCDSiCCDS26610.1
UniGeneiMm.379136

Similar proteinsi

Entry informationi

Entry nameiQCR7_MOUSE
AccessioniPrimary (citable) accession number: Q9D855
Secondary accession number(s): Q8K2E2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 122 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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