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Q9D832 (DNJB4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DnaJ homolog subfamily B member 4
Gene names
Name:Dnajb4
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable chaperone By similarity.

Subunit structure

Homodimer. The C-terminal section interacts with the C-terminal tail of OPRM1. Interacts also with SDIM1 By similarity.

Sequence similarities

Contains 1 J domain.

Ontologies

Keywords
   Molecular functionChaperone
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: Ensembl

plasma membrane

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 337336DnaJ homolog subfamily B member 4
PRO_0000071022

Regions

Domain4 – 6865J

Amino acid modifications

Modified residue1221Phosphoserine By similarity
Modified residue1481Phosphoserine By similarity

Experimental info

Sequence conflict661Q → L in BAB24608. Ref.1
Sequence conflict1511P → T in BAB24608. Ref.1
Sequence conflict3291I → S in BAB24608. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9D832 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: BEE4A0E25BCEEFF4

FASTA33737,782
        10         20         30         40         50         60 
MGKDYYHILG IDKGATDEDV KKAYRKQALK FHPDKNKSPQ AEEKFKEVAE AYEVLSDPKK 

        70         80         90        100        110        120 
REIYDQFGEE GLKGGAGGTD GQGGTFRYTF HGDPHATFAA FFGGSNPFEI FFGRRMGGGR 

       130        140        150        160        170        180 
DSEEMEIDGD PFSAFGFSMN GYPRDRNSVG PSRLKQDPPI IHELKVSLEE IYSGCTKRMK 

       190        200        210        220        230        240 
ISRKRLNPDG RSYRSEDKIL TIEIKKGWKE GTKITFPREG DETPNSIPAD IVFVIKDKEH 

       250        260        270        280        290        300 
PKFKRDGSNI VYTAKISLRE ALCGCSLNVP TMDGRNLPMS VTDIVKPGMR RRVIGYGLPF 

       310        320        330 
PKNPDQRGDL LIEFDVSFPD VISAASKEIL RKHLPAS 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Cerebellum, Egg, Small intestine and Testis.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK006478 mRNA. Translation: BAB24608.1.
AK008537 mRNA. Translation: BAB25729.1.
AK028049 mRNA. Translation: BAC25720.1.
AK136240 mRNA. Translation: BAE22891.1.
AK162194 mRNA. Translation: BAE36783.1.
BC017161 mRNA. Translation: AAH17161.1.
CCDSCCDS17915.1.
RefSeqNP_080202.1. NM_025926.4.
NP_081563.2. NM_027287.4.
XP_006501982.1. XM_006501919.1.
XP_006501983.1. XM_006501920.1.
UniGeneMm.458538.
Mm.46746.

3D structure databases

ProteinModelPortalQ9D832.
SMRQ9D832. Positions 1-335.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9D832. 3 interactions.
MINTMINT-4093222.
STRING10090.ENSMUSP00000029669.

PTM databases

PhosphoSiteQ9D832.

Proteomic databases

MaxQBQ9D832.
PaxDbQ9D832.
PRIDEQ9D832.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000029669; ENSMUSP00000029669; ENSMUSG00000028035.
ENSMUST00000050073; ENSMUSP00000053916; ENSMUSG00000028035.
ENSMUST00000144950; ENSMUSP00000114356; ENSMUSG00000028035.
GeneID67035.
KEGGmmu:67035.
UCSCuc008rsq.2. mouse.

Organism-specific databases

CTD11080.
MGIMGI:1914285. Dnajb4.

Phylogenomic databases

eggNOGCOG2214.
GeneTreeENSGT00720000108438.
HOGENOMHOG000226718.
HOVERGENHBG066727.
InParanoidQ9D832.
KOK09510.
OMAIEFDVSF.
OrthoDBEOG7TF79F.
PhylomeDBQ9D832.
TreeFamTF105141.

Gene expression databases

BgeeQ9D832.
CleanExMM_DNAJB4.
GenevestigatorQ9D832.

Family and domain databases

Gene3D1.10.287.110. 1 hit.
InterProIPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
[Graphical view]
PfamPF01556. CTDII. 1 hit.
PF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSPR00625. JDOMAIN.
SMARTSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio323364.
PROQ9D832.
SOURCESearch...

Entry information

Entry nameDNJB4_MOUSE
AccessionPrimary (citable) accession number: Q9D832
Secondary accession number(s): Q3TS92, Q9D9U2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot