Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DnaJ homolog subfamily B member 4

Gene

Dnajb4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Probable chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily B member 4
Gene namesi
Name:Dnajb4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1914285. Dnajb4.

Subcellular locationi

  • Cytoplasm By similarity
  • Cell membrane By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000710222 – 337DnaJ homolog subfamily B member 4Add BLAST336

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei122PhosphoserineBy similarity1
Modified residuei148PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9D832.
MaxQBiQ9D832.
PaxDbiQ9D832.
PeptideAtlasiQ9D832.
PRIDEiQ9D832.

PTM databases

iPTMnetiQ9D832.
PhosphoSitePlusiQ9D832.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028035.
CleanExiMM_DNAJB4.
ExpressionAtlasiQ9D832. baseline and differential.
GenevisibleiQ9D832. MM.

Interactioni

Subunit structurei

Homodimer. The C-terminal section interacts with the C-terminal tail of OPRM1. Interacts also with SDIM1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9D832. 3 interactors.
MINTiMINT-4093222.
STRINGi10090.ENSMUSP00000029669.

Structurei

3D structure databases

ProteinModelPortaliQ9D832.
SMRiQ9D832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 68JPROSITE-ProRule annotationAdd BLAST65

Sequence similaritiesi

Contains 1 J domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ9D832.
KOiK09510.
OMAiMDGRTIP.
OrthoDBiEOG091G0DLS.
PhylomeDBiQ9D832.
TreeFamiTF105141.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiIPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKDYYHILG IDKGATDEDV KKAYRKQALK FHPDKNKSPQ AEEKFKEVAE
60 70 80 90 100
AYEVLSDPKK REIYDQFGEE GLKGGAGGTD GQGGTFRYTF HGDPHATFAA
110 120 130 140 150
FFGGSNPFEI FFGRRMGGGR DSEEMEIDGD PFSAFGFSMN GYPRDRNSVG
160 170 180 190 200
PSRLKQDPPI IHELKVSLEE IYSGCTKRMK ISRKRLNPDG RSYRSEDKIL
210 220 230 240 250
TIEIKKGWKE GTKITFPREG DETPNSIPAD IVFVIKDKEH PKFKRDGSNI
260 270 280 290 300
VYTAKISLRE ALCGCSLNVP TMDGRNLPMS VTDIVKPGMR RRVIGYGLPF
310 320 330
PKNPDQRGDL LIEFDVSFPD VISAASKEIL RKHLPAS
Length:337
Mass (Da):37,782
Last modified:June 1, 2001 - v1
Checksum:iBEE4A0E25BCEEFF4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti66Q → L in BAB24608 (PubMed:16141072).Curated1
Sequence conflicti151P → T in BAB24608 (PubMed:16141072).Curated1
Sequence conflicti329I → S in BAB24608 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006478 mRNA. Translation: BAB24608.1.
AK008537 mRNA. Translation: BAB25729.1.
AK028049 mRNA. Translation: BAC25720.1.
AK136240 mRNA. Translation: BAE22891.1.
AK162194 mRNA. Translation: BAE36783.1.
BC017161 mRNA. Translation: AAH17161.1.
CCDSiCCDS17915.1.
RefSeqiNP_080202.1. NM_025926.4.
NP_081563.2. NM_027287.4.
XP_006501983.1. XM_006501920.3.
UniGeneiMm.458538.
Mm.46746.

Genome annotation databases

EnsembliENSMUST00000029669; ENSMUSP00000029669; ENSMUSG00000028035.
ENSMUST00000050073; ENSMUSP00000053916; ENSMUSG00000028035.
ENSMUST00000144950; ENSMUSP00000114356; ENSMUSG00000028035.
GeneIDi67035.
KEGGimmu:67035.
UCSCiuc008rsq.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006478 mRNA. Translation: BAB24608.1.
AK008537 mRNA. Translation: BAB25729.1.
AK028049 mRNA. Translation: BAC25720.1.
AK136240 mRNA. Translation: BAE22891.1.
AK162194 mRNA. Translation: BAE36783.1.
BC017161 mRNA. Translation: AAH17161.1.
CCDSiCCDS17915.1.
RefSeqiNP_080202.1. NM_025926.4.
NP_081563.2. NM_027287.4.
XP_006501983.1. XM_006501920.3.
UniGeneiMm.458538.
Mm.46746.

3D structure databases

ProteinModelPortaliQ9D832.
SMRiQ9D832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9D832. 3 interactors.
MINTiMINT-4093222.
STRINGi10090.ENSMUSP00000029669.

PTM databases

iPTMnetiQ9D832.
PhosphoSitePlusiQ9D832.

Proteomic databases

EPDiQ9D832.
MaxQBiQ9D832.
PaxDbiQ9D832.
PeptideAtlasiQ9D832.
PRIDEiQ9D832.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000029669; ENSMUSP00000029669; ENSMUSG00000028035.
ENSMUST00000050073; ENSMUSP00000053916; ENSMUSG00000028035.
ENSMUST00000144950; ENSMUSP00000114356; ENSMUSG00000028035.
GeneIDi67035.
KEGGimmu:67035.
UCSCiuc008rsq.3. mouse.

Organism-specific databases

CTDi11080.
MGIiMGI:1914285. Dnajb4.

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ9D832.
KOiK09510.
OMAiMDGRTIP.
OrthoDBiEOG091G0DLS.
PhylomeDBiQ9D832.
TreeFamiTF105141.

Miscellaneous databases

PROiQ9D832.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028035.
CleanExiMM_DNAJB4.
ExpressionAtlasiQ9D832. baseline and differential.
GenevisibleiQ9D832. MM.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiIPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNJB4_MOUSE
AccessioniPrimary (citable) accession number: Q9D832
Secondary accession number(s): Q3TS92, Q9D9U2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.