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Protein

Distal membrane-arm assembly complex protein 2

Gene

Dmac2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Distal membrane-arm assembly complex protein 2By similarity
Alternative name(s):
ATP synthase subunit s-like proteinCurated
Gene namesi
Name:Dmac2
Synonyms:Atp5slImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1913599. Atp5sl.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003186971 – 258Distal membrane-arm assembly complex protein 2Add BLAST258

Proteomic databases

EPDiQ9D7K5.
MaxQBiQ9D7K5.
PaxDbiQ9D7K5.
PRIDEiQ9D7K5.

PTM databases

PhosphoSitePlusiQ9D7K5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000057229.
CleanExiMM_ATP5SL.
ExpressionAtlasiQ9D7K5. baseline and differential.
GenevisibleiQ9D7K5. MM.

Interactioni

Subunit structurei

Interacts with incompletely assembled mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083115.

Structurei

3D structure databases

ProteinModelPortaliQ9D7K5.
SMRiQ9D7K5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP synthase subunit s family.Curated

Phylogenomic databases

eggNOGiENOG410IS4E. Eukaryota.
ENOG4111PMF. LUCA.
GeneTreeiENSGT00530000063680.
HOGENOMiHOG000034116.
HOVERGENiHBG056046.
InParanoidiQ9D7K5.
OMAiFRDKEWI.
OrthoDBiEOG091G07CX.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiView protein in InterPro
IPR032675. L_dom-like.

Sequencei

Sequence statusi: Complete.

Q9D7K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPRAVLHL GAREWNGRAR RIHGMSELVT PDSSREKKRT LLQFLSDHFQ
60 70 80 90 100
DIQTLREYLL QKQISKVNRE NRSFTNIQEK YGPYVAGAVF ILKQGGAVKF
110 120 130 140 150
QDKEEWIRPN NRSHFLAEIQ KFQNVPVEAV DASGCAINYQ GLSNLLPLKE
160 170 180 190 200
LRSLSLQRCP NLDDWCLSRL YLLAGSLQEL SLAGCPRISE RGLACLHHLQ
210 220 230 240 250
NLRRLDISDL PAVSHPGLTQ ILVEEMLPHC EVLGADWAQN LKLEPDKQPP

DTSTPLSS
Length:258
Mass (Da):29,179
Last modified:June 1, 2001 - v1
Checksum:iC43E4A5C986CE7F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009150 mRNA. Translation: BAB26107.1.
CCDSiCCDS71917.1.
RefSeqiNP_001277416.1. NM_001290487.1.
UniGeneiMm.159956.

Genome annotation databases

EnsembliENSMUST00000077338; ENSMUSP00000076563; ENSMUSG00000057229.
GeneIDi66349.
KEGGimmu:66349.
UCSCiuc009fte.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiDMAC2_MOUSE
AccessioniPrimary (citable) accession number: Q9D7K5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2001
Last modified: September 27, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families