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Protein

Serpin A9

Gene

Serpina9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin A9
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1919157. Serpina9.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000004197226 – 418Serpin A9Add BLAST393

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi103N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi213N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi224N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9D7D2.
PRIDEiQ9D7D2.

PTM databases

iPTMnetiQ9D7D2.
PhosphoSitePlusiQ9D7D2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000058260.
ExpressionAtlasiQ9D7D2. baseline and differential.
GenevisibleiQ9D7D2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000058535.

Structurei

3D structure databases

ProteinModelPortaliQ9D7D2.
SMRiQ9D7D2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00760000118839.
HOGENOMiHOG000238521.
HOVERGENiHBG005957.
InParanoidiQ9D7D2.
KOiK04525.
OMAiFQHLVHS.
OrthoDBiEOG091G0ION.
PhylomeDBiQ9D7D2.
TreeFamiTF343201.

Family and domain databases

InterProiView protein in InterPro
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D7D2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSSSFYRVL LLVGFCAPIF CMLSSNPYNQ ESSHLPSMKK NPASQVSPSN
60 70 80 90 100
TRFSFLLYQR LAQENPGQNI LFSPVSISTS LAMLSLGARS ATKTQILRTL
110 120 130 140 150
GFNFTWVSEP TIHMGFEYLV RSLNKCHQGR ELRMGSVLFI RKELQLQATF
160 170 180 190 200
LDRVKKLYGA KVFSEDFSNA ATAQAQINSY VEKETKGKVV DVIQDLDSQT
210 220 230 240 250
AMVLVNHIFF KANWTQPFST ANTNKSFPFL LSKGTTVHVP MMHQTESFAF
260 270 280 290 300
GVDKELGCSI LQMDYRGDAV AFFVLPGKGK MRQLEKSLSA RRLRKWSRSL
310 320 330 340 350
QKRWIKVFIP KFSISASYNL ETILPKMGIR DAFNSNADFS GITKTHFLQV
360 370 380 390 400
SKAAHKAVLD VSEEGTEAAA ATTTKLIVRS RDTPSSIIAF KEPFLILLLD
410
KNTESVLFLG KVENPRKM
Length:418
Mass (Da):46,894
Last modified:June 1, 2001 - v1
Checksum:i4CFA144E99381D2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009343 mRNA. Translation: BAB26230.1.
CCDSiCCDS26144.1.
RefSeqiNP_082273.1. NM_027997.2.
XP_006516304.1. XM_006516241.1.
XP_006516305.1. XM_006516242.2.
UniGeneiMm.326723.

Genome annotation databases

EnsembliENSMUST00000058464; ENSMUSP00000058535; ENSMUSG00000058260.
GeneIDi71907.
KEGGimmu:71907.
UCSCiuc007owo.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiSPA9_MOUSE
AccessioniPrimary (citable) accession number: Q9D7D2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: June 1, 2001
Last modified: June 7, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families