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Q9D7D2 (SPA9_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serpin A9
Gene names
Name:Serpina9
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the serpin family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionProtease inhibitor
Serine protease inhibitor
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of proteolysis

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type endopeptidase inhibitor activity

Inferred from sequence or structural similarity. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 418393Serpin A9
PRO_0000041972

Amino acid modifications

Glycosylation1031N-linked (GlcNAc...) Potential
Glycosylation2131N-linked (GlcNAc...) Potential
Glycosylation2241N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9D7D2 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 4CFA144E99381D2D

FASTA41846,894
        10         20         30         40         50         60 
MGSSSFYRVL LLVGFCAPIF CMLSSNPYNQ ESSHLPSMKK NPASQVSPSN TRFSFLLYQR 

        70         80         90        100        110        120 
LAQENPGQNI LFSPVSISTS LAMLSLGARS ATKTQILRTL GFNFTWVSEP TIHMGFEYLV 

       130        140        150        160        170        180 
RSLNKCHQGR ELRMGSVLFI RKELQLQATF LDRVKKLYGA KVFSEDFSNA ATAQAQINSY 

       190        200        210        220        230        240 
VEKETKGKVV DVIQDLDSQT AMVLVNHIFF KANWTQPFST ANTNKSFPFL LSKGTTVHVP 

       250        260        270        280        290        300 
MMHQTESFAF GVDKELGCSI LQMDYRGDAV AFFVLPGKGK MRQLEKSLSA RRLRKWSRSL 

       310        320        330        340        350        360 
QKRWIKVFIP KFSISASYNL ETILPKMGIR DAFNSNADFS GITKTHFLQV SKAAHKAVLD 

       370        380        390        400        410 
VSEEGTEAAA ATTTKLIVRS RDTPSSIIAF KEPFLILLLD KNTESVLFLG KVENPRKM

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Tongue.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK009343 mRNA. Translation: BAB26230.1.
IPIIPI00110173.
RefSeqNP_082273.1. NM_027997.2.
UniGeneMm.326723.

3D structure databases

ProteinModelPortalQ9D7D2.
SMRQ9D7D2. Positions 45-415.
ModBaseSearch...

Protein family/group databases

MEROPSI04.955.

PTM databases

PhosphoSiteQ9D7D2.

Proteomic databases

PRIDEQ9D7D2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000058464; ENSMUSP00000058535; ENSMUSG00000058260.
GeneID71907.
KEGGmmu:71907.
UCSCuc007owo.1. mouse.

Organism-specific databases

CTD327657.
MGIMGI:1919157. Serpina9.

Phylogenomic databases

eggNOGCOG4826.
GeneTreeENSGT00700000104474.
HOGENOMHOG000238521.
HOVERGENHBG005957.
InParanoidQ9D7D2.
OMAGFQHLVH.
OrthoDBEOG4B2SX7.

Gene expression databases

ArrayExpressQ9D7D2.
BgeeQ9D7D2.
GenevestigatorQ9D7D2.
GermOnlineENSMUSG00000058260. Mus musculus.

Family and domain databases

InterProIPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. Prot_inh_serpin. 1 hit.
PROSITEPS00284. SERPIN. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio334906.
SOURCESearch...

Entry information

Entry nameSPA9_MOUSE
AccessionPrimary (citable) accession number: Q9D7D2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: June 1, 2001
Last modified: May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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