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Protein

Tubulin epsilon chain

Gene

Tube1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi148 – 1547GTPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin epsilon chain
Alternative name(s):
Epsilon-tubulin
Gene namesi
Name:Tube1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1919174. Tube1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Tubulin epsilon chainPRO_0000233352Add
BLAST

Proteomic databases

EPDiQ9D6T1.
MaxQBiQ9D6T1.
PaxDbiQ9D6T1.
PeptideAtlasiQ9D6T1.
PRIDEiQ9D6T1.

PTM databases

PhosphoSiteiQ9D6T1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000019845.
CleanExiMM_TUBE1.
GenevisibleiQ9D6T1. MM.

Interactioni

Protein-protein interaction databases

BioGridi215035. 35 interactions.
IntActiQ9D6T1. 34 interactions.
STRINGi10090.ENSMUSP00000019991.

Structurei

3D structure databases

ProteinModelPortaliQ9D6T1.
SMRiQ9D6T1. Positions 1-460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tubulin family.Curated

Phylogenomic databases

eggNOGiKOG1375. Eukaryota.
COG5023. LUCA.
GeneTreeiENSGT00760000119061.
HOGENOMiHOG000165713.
HOVERGENiHBG098062.
InParanoidiQ9D6T1.
KOiK10391.
OMAiQEGWKTG.
OrthoDBiEOG091G06O0.
PhylomeDBiQ9D6T1.
TreeFamiTF330882.

Family and domain databases

Gene3Di1.10.287.600. 1 hit.
3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiIPR004057. Epsilon_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR023123. Tubulin_C.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PANTHERiPTHR11588. PTHR11588. 2 hits.
PTHR11588:SF13. PTHR11588:SF13. 2 hits.
PfamiPF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
[Graphical view]
PRINTSiPR01519. EPSLNTUBULIN.
PR01161. TUBULIN.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 2 hits.
SSF55307. SSF55307. 1 hit.
PROSITEiPS00227. TUBULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D6T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQSVVVQVG QCGNQIGCCF WDLALREHAA VNQKGIYDDA ISSFFRNVDT
60 70 80 90 100
RAVGDGGSIS KGRISSLKAR AVLIDMEEGV VNEILQGPLR DVFDSKQLIT
110 120 130 140 150
DISGSGNNWA VGHKVFGCLY REQILEKLRK SAEQCDCLQC FFIIHSMGGG
160 170 180 190 200
TGSGLGTFLL KVLEDEFPEV YRFVTAVYPS SEDDVITSPY NSMLAMKELN
210 220 230 240 250
EHADCVLPID NQSLFDIISK IDLVVNSGKL GSAVKPKSLI TSNMGAVKKH
260 270 280 290 300
HKKPFDAMNN IVANLLLSLT SSARFEGSLN MDLNEISMNL VPFPKLHYLV
310 320 330 340 350
SSLTPLYTLA DVNIPPRRLD QMFSDAFSKD HQLIQADPRH SLYLACALIV
360 370 380 390 400
RGNVQISDLR RNIERLKPAL QFVSWNQEGW KTSLCSVPPV GHSHSLLALA
410 420 430 440 450
NNTCVKPTFM ELRERFTRLY KKKAHLHHYL QVDGMEESTF TEAVSSLSAL
460 470
IQEYSDLDAT KSLPVPDVPR LSVAL
Length:475
Mass (Da):52,652
Last modified:June 1, 2001 - v1
Checksum:iD5CA050DD7DE0DD1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010005 mRNA. Translation: BAB26636.1.
AK148039 mRNA. Translation: BAE28305.1.
BC062179 mRNA. Translation: AAH62179.1.
CCDSiCCDS23787.1.
RefSeqiNP_082282.1. NM_028006.2.
UniGeneiMm.297956.

Genome annotation databases

EnsembliENSMUST00000019991; ENSMUSP00000019991; ENSMUSG00000019845.
GeneIDi71924.
KEGGimmu:71924.
UCSCiuc007evu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010005 mRNA. Translation: BAB26636.1.
AK148039 mRNA. Translation: BAE28305.1.
BC062179 mRNA. Translation: AAH62179.1.
CCDSiCCDS23787.1.
RefSeqiNP_082282.1. NM_028006.2.
UniGeneiMm.297956.

3D structure databases

ProteinModelPortaliQ9D6T1.
SMRiQ9D6T1. Positions 1-460.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi215035. 35 interactions.
IntActiQ9D6T1. 34 interactions.
STRINGi10090.ENSMUSP00000019991.

PTM databases

PhosphoSiteiQ9D6T1.

Proteomic databases

EPDiQ9D6T1.
MaxQBiQ9D6T1.
PaxDbiQ9D6T1.
PeptideAtlasiQ9D6T1.
PRIDEiQ9D6T1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000019991; ENSMUSP00000019991; ENSMUSG00000019845.
GeneIDi71924.
KEGGimmu:71924.
UCSCiuc007evu.1. mouse.

Organism-specific databases

CTDi51175.
MGIiMGI:1919174. Tube1.

Phylogenomic databases

eggNOGiKOG1375. Eukaryota.
COG5023. LUCA.
GeneTreeiENSGT00760000119061.
HOGENOMiHOG000165713.
HOVERGENiHBG098062.
InParanoidiQ9D6T1.
KOiK10391.
OMAiQEGWKTG.
OrthoDBiEOG091G06O0.
PhylomeDBiQ9D6T1.
TreeFamiTF330882.

Miscellaneous databases

PROiQ9D6T1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019845.
CleanExiMM_TUBE1.
GenevisibleiQ9D6T1. MM.

Family and domain databases

Gene3Di1.10.287.600. 1 hit.
3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiIPR004057. Epsilon_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR023123. Tubulin_C.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PANTHERiPTHR11588. PTHR11588. 2 hits.
PTHR11588:SF13. PTHR11588:SF13. 2 hits.
PfamiPF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
[Graphical view]
PRINTSiPR01519. EPSLNTUBULIN.
PR01161. TUBULIN.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 2 hits.
SSF55307. SSF55307. 1 hit.
PROSITEiPS00227. TUBULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBE_MOUSE
AccessioniPrimary (citable) accession number: Q9D6T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.