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Protein

ADP-ribosylation factor-like protein 5B

Gene

Arl5b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Binds and exchanges GTP and GDP.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei159GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30GTPBy similarity8
Nucleotide bindingi66 – 70GTPBy similarity5
Nucleotide bindingi125 – 128GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 5B
Alternative name(s):
ADP-ribosylation factor-like protein 8
Gene namesi
Name:Arl5b
Synonyms:Arl8
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1923119. Arl5b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedSequence analysis
ChainiPRO_00002074712 – 179ADP-ribosylation factor-like protein 5BAdd BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineSequence analysis1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

PaxDbiQ9D4P0.
PRIDEiQ9D4P0.

PTM databases

PhosphoSitePlusiQ9D4P0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000017418.
CleanExiMM_ARL5B.

Interactioni

Protein-protein interaction databases

BioGridi217808. 1 interactor.
IntActiQ9D4P0. 1 interactor.
STRINGi10090.ENSMUSP00000069725.

Structurei

3D structure databases

ProteinModelPortaliQ9D4P0.
SMRiQ9D4P0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
HOVERGENiHBG002073.
InParanoidiQ9D4P0.
KOiK07950.
OMAiEWMTSRA.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D4P0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLIFAKLWS LFCNQEHKVI IVGLDNAGKT TILYQFLMNE VVHTSPTIGS
60 70 80 90 100
NVEEIVVKNT HFLMWDIGGQ ESLRSSWNTY YSNTEFIILV VDSIDRERLA
110 120 130 140 150
ITKEELYRML AHEDLRKAAV LIFANKQDMK GCMTAAEISK YLTLSSIKDH
160 170
PWHIQSCCAL TGEGLCQGLE WMTSRIGVR
Length:179
Mass (Da):20,375
Last modified:September 19, 2003 - v3
Checksum:iECD74C4EA1A80E33
GO

Sequence cautioni

The sequence BAB30204 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC30872 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC35496 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK016359 mRNA. Translation: BAB30204.2. Different initiation.
AK040422 mRNA. Translation: BAC30591.1.
AK041237 mRNA. Translation: BAC30872.1. Different initiation.
AK042200 mRNA. Translation: BAC31195.1.
AK053731 mRNA. Translation: BAC35496.1. Different initiation.
AK164341 mRNA. Translation: BAE37748.1.
RefSeqiNP_083742.2. NM_029466.4.
UniGeneiMm.174068.

Genome annotation databases

GeneIDi75869.
KEGGimmu:75869.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK016359 mRNA. Translation: BAB30204.2. Different initiation.
AK040422 mRNA. Translation: BAC30591.1.
AK041237 mRNA. Translation: BAC30872.1. Different initiation.
AK042200 mRNA. Translation: BAC31195.1.
AK053731 mRNA. Translation: BAC35496.1. Different initiation.
AK164341 mRNA. Translation: BAE37748.1.
RefSeqiNP_083742.2. NM_029466.4.
UniGeneiMm.174068.

3D structure databases

ProteinModelPortaliQ9D4P0.
SMRiQ9D4P0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi217808. 1 interactor.
IntActiQ9D4P0. 1 interactor.
STRINGi10090.ENSMUSP00000069725.

PTM databases

PhosphoSitePlusiQ9D4P0.

Proteomic databases

PaxDbiQ9D4P0.
PRIDEiQ9D4P0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi75869.
KEGGimmu:75869.

Organism-specific databases

CTDi221079.
MGIiMGI:1923119. Arl5b.

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
HOVERGENiHBG002073.
InParanoidiQ9D4P0.
KOiK07950.
OMAiEWMTSRA.

Miscellaneous databases

ChiTaRSiArl5b. mouse.
PROiQ9D4P0.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017418.
CleanExiMM_ARL5B.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARL5B_MOUSE
AccessioniPrimary (citable) accession number: Q9D4P0
Secondary accession number(s): Q8BFU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: September 19, 2003
Last modified: November 2, 2016
This is version 100 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.