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Q9D485

- EFHC2_MOUSE

UniProt

Q9D485 - EFHC2_MOUSE

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Protein

EF-hand domain-containing family member C2

Gene
Efhc2
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
EF-hand domain-containing family member C2
Gene namesi
Name:Efhc2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1921655. Efhc2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 750750EF-hand domain-containing family member C2PRO_0000251704Add
BLAST

Proteomic databases

PaxDbiQ9D485.
PRIDEiQ9D485.

PTM databases

PhosphoSiteiQ9D485.

Expressioni

Gene expression databases

ArrayExpressiQ9D485.
BgeeiQ9D485.
CleanExiMM_EFHC2.
GenevestigatoriQ9D485.

Structurei

3D structure databases

ProteinModelPortaliQ9D485.
SMRiQ9D485. Positions 71-188, 637-697.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 182108DM10 1Add
BLAST
Domaini226 – 368143DM10 2Add
BLAST
Domaini430 – 537108DM10 3Add
BLAST
Domaini557 – 59236EF-handAdd
BLAST

Sequence similaritiesi

Contains 3 DM10 domains.
Contains 1 EF-hand domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG282456.
GeneTreeiENSGT00530000063528.
HOGENOMiHOG000265451.
HOVERGENiHBG059646.
InParanoidiQ9D485.
OMAiMEKDSYG.
OrthoDBiEOG7BGHK3.
PhylomeDBiQ9D485.
TreeFamiTF314504.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR010554. DUF1126.
IPR011992. EF-hand-dom_pair.
IPR006602. Uncharacterised_DM10.
[Graphical view]
PfamiPF06565. DUF1126. 3 hits.
[Graphical view]
SMARTiSM00676. DM10. 3 hits.
[Graphical view]
PROSITEiPS51336. DM10. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D485-1 [UniParc]FASTAAdd to Basket

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MALPFLPGNS FNRNIGKERF HKSQHWGFCN NVRMLVSENK PGVGGDLLYG    50
QKIKPKHSVF PKGDGTDAPS WVAFDKQVLS FDAYLEDEIS DKRQEIFRIR 100
YYKIYFYLED DTIQVNEPEV INSGLPQGTS IRRQRIPYPP PNDDQFYTVY 150
DFNINISVVF YGRTFKIYDC DPFTKNFLKK IGIKLNPPGQ CPLDPYMKMR 200
RETLEFVDPF RPYQSFDTLK RFIQYDGKVL RFFCLWDDST SLFGDRREFV 250
LHYFLCDGTV EIREVLPSNS GRDAMSSFLR RGKLPKYGPP GIYQPGQITD 300
RAVLNVYGGL SEWRADGYLL DKYQLGKVEQ DFYTDQDLSI GATINVWGRK 350
VLLCDCDEFT KTYYRTKYGV DNFTPISCKP PHLPKIERKY PPYTGFGSEE 400
DSFRSCVGLK PTPHRKNFKK FMELDSFGNI SNILRYFGKL ITHKCADVDR 450
IFVIAFYLSD DTISVFEPIE NNSGNAGGMF LKRSRVKKPG QEVFKSEFSE 500
YIKAEELYIG ATVNINGYLF ILLNADEYTL NYMENNTDKF PYSNFELAIQ 550
KLKQEKSKSR EITQVFAAAD YNHTKVVPYN TFRDILMSIT MGKLIDQELI 600
TIARHYRVPE IMDPDLAYLI ARAHEKFKKN IFENFDMFIY NCVYEDREKK 650
GVLPTKDIRR MCKSSRLPLD DDFLDCLLSR FEDKDHQINY EIFFSVLNWR 700
MNPTPDLQAP PYLKEKCEDV WVGMPSPIPV KYVRYLDFLI DVYGLEDNML 750
Length:750
Mass (Da):87,646
Last modified:October 3, 2006 - v2
Checksum:i382AF75FDB9CB052
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti381 – 3811P → S in BAB30393. 1 Publication
Sequence conflicti578 – 5781P → T in BAC26479. 1 Publication
Sequence conflicti674 – 6741L → V in BAC26479. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK016714 mRNA. Translation: BAB30393.1.
AK029501 mRNA. Translation: BAC26479.1.
BC120659 mRNA. Translation: AAI20660.1.
CCDSiCCDS40883.1.
RefSeqiNP_083192.2. NM_028916.4.
XP_006527768.1. XM_006527705.1.
UniGeneiMm.248531.

Genome annotation databases

EnsembliENSMUST00000026014; ENSMUSP00000026014; ENSMUSG00000025038.
GeneIDi74405.
KEGGimmu:74405.
UCSCiuc009sse.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK016714 mRNA. Translation: BAB30393.1 .
AK029501 mRNA. Translation: BAC26479.1 .
BC120659 mRNA. Translation: AAI20660.1 .
CCDSi CCDS40883.1.
RefSeqi NP_083192.2. NM_028916.4.
XP_006527768.1. XM_006527705.1.
UniGenei Mm.248531.

3D structure databases

ProteinModelPortali Q9D485.
SMRi Q9D485. Positions 71-188, 637-697.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9D485.

Proteomic databases

PaxDbi Q9D485.
PRIDEi Q9D485.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000026014 ; ENSMUSP00000026014 ; ENSMUSG00000025038 .
GeneIDi 74405.
KEGGi mmu:74405.
UCSCi uc009sse.2. mouse.

Organism-specific databases

CTDi 80258.
MGIi MGI:1921655. Efhc2.

Phylogenomic databases

eggNOGi NOG282456.
GeneTreei ENSGT00530000063528.
HOGENOMi HOG000265451.
HOVERGENi HBG059646.
InParanoidi Q9D485.
OMAi MEKDSYG.
OrthoDBi EOG7BGHK3.
PhylomeDBi Q9D485.
TreeFami TF314504.

Miscellaneous databases

NextBioi 340665.
PROi Q9D485.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9D485.
Bgeei Q9D485.
CleanExi MM_EFHC2.
Genevestigatori Q9D485.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR010554. DUF1126.
IPR011992. EF-hand-dom_pair.
IPR006602. Uncharacterised_DM10.
[Graphical view ]
Pfami PF06565. DUF1126. 3 hits.
[Graphical view ]
SMARTi SM00676. DM10. 3 hits.
[Graphical view ]
PROSITEi PS51336. DM10. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Testis.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiEFHC2_MOUSE
AccessioniPrimary (citable) accession number: Q9D485
Secondary accession number(s): Q0VBF5, Q8CDV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 3, 2006
Last modified: July 9, 2014
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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